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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
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Amos Bairoch

PROSITE documentation PDOC00812
Flagella transport protein fliP family signatures


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PURL: https://purl.expasy.org/prosite/documentation/PDOC00812

Description

In Escherichia coli and related proteins the fliP protein probably [1] plays a role in the transport of flagellar proteins. FliP is a protein of about 30 Kd which contains three or four transmembrane regions. Proteins evolutionary related to fliP have been found in a wide range of bacteria (mopC, hrcR, hrpW, spaP, yscR, etc.) and are involved in a variety of signal-peptide independent secretion systems.

We developed two signature patterns for this family of proteins. These patterns are located in the C-terminal part of these proteins and overlap with parts of the last two transmembrane regions.

Last update:

December 2004 / Pattern and text revised.

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Technical section

PROSITE methods (with tools and information) covered by this documentation:

FLIP_1, PS01060; Flagella transport protein fliP family signature 1  (PATTERN)

FLIP_2, PS01061; Flagella transport protein fliP family signature 2  (PATTERN)


Reference

1AuthorsMalakooti J. Ely B. Matsumura P.
TitleMolecular characterization, nucleotide sequence, and expression of the fliO, fliP, fliQ, and fliR genes of Escherichia coli.
SourceJ. Bacteriol. 176:189-197(1994).
PubMed ID8282695



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