PROSITE documentation PDOC00812
Flagella transport protein fliP family signatures


In Escherichia coli and related proteins the fliP protein probably [1] plays a role in the transport of flagellar proteins. FliP is a protein of about 30 Kd which contains three or four transmembrane regions. Proteins evolutionary related to fliP have been found in a wide range of bacteria (mopC, hrcR, hrpW, spaP, yscR, etc.) and are involved in a variety of signal-peptide independent secretion systems.

We developed two signature patterns for this family of proteins. These patterns are located in the C-terminal part of these proteins and overlap with parts of the last two transmembrane regions.

Last update:

December 2004 / Pattern and text revised.


Technical section

PROSITE methods (with tools and information) covered by this documentation:

FLIP_1, PS01060; Flagella transport protein fliP family signature 1  (PATTERN)

FLIP_2, PS01061; Flagella transport protein fliP family signature 2  (PATTERN)


1AuthorsMalakooti J. Ely B. Matsumura P.
TitleMolecular characterization, nucleotide sequence, and expression of the fliO, fliP, fliQ, and fliR genes of Escherichia coli.
SourceJ. Bacteriol. 176:189-197(1994).
PubMed ID8282695

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