PROSITE documentation PDOC00841Hydrogenases expression/synthesis hupF/hypC family signature
Description
Bacterial membrane-bound nickel-dependent hydrogenases require a number of gene products for their expression and/or synthesis [1]. Among these genes, there is a group that codes for a family of small proteins (from 80 to 110 residues). The proteins that are known to belong to this family are:
- Alcaligenes eutrophus and Azotobacter vinelandii hoxL and hypC.
- Rhizobium leguminosarum and Rhodobacter capsulatus hupF and hypC.
- Escherichia coli hypC and hybG.
- Methanococcus jannaschii hypothetical protein MJ0200.
All these proteins start with a conserved Met-Cys dipeptide.
Last update:November 1997 / Pattern and text revised.
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Reference
1 | Authors | Colbeau A. Richaud P. Toussaint B. Caballero F.J. Elster C. Delphin C. Smith R.L. Chabert J. Vignais P.M. |
Title | Organization of the genes necessary for hydrogenase expression in Rhodobacter capsulatus. Sequence analysis and identification of two hyp regulatory mutants. | |
Source | Mol. Microbiol. 8:15-29(1993). | |
PubMed ID | 8497190 |
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