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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE documentation PDOC00890
GPR1/FUN34/yaaH family signature


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PURL: https://purl.expasy.org/prosite/documentation/PDOC00890

Description

The following uncharacterized proteins are evolutionary related:

  • Yarrowia lipolytica glyxoxylate pathway regulator GPR1.
  • Yeast protein FUN34.
  • Yeast hypothetical protein YCR10c.
  • Yeast hypothetical protein YDR384c.
  • Fission yeast hypothetical protein SpAC5D6.09c.
  • Escherichia coli hypothetical protein yaaH.
  • Methanobacterium thermoautotrophicum hypothetical protein Mth215.

They are hydrophobic proteins that seem to contain six transmembrane regions and which could therefore be involved in transport. They have from 188 to 283 amino acids. As a signature pattern, we selected a conserved region located at the N-terminal part of the first potential transmembrane region.

Last update:

July 1998 / Pattern and text revised.

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Technical section

PROSITE method (with tools and information) covered by this documentation:

GPR1_FUN34_YAAH, PS01114; GPR1/FUN34/yaaH family signature  (PATTERN)


Reference



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