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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE documentation PDOC00931
Uncharacterized protein family UPF0001 signature


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PURL: https://purl.expasy.org/prosite/documentation/PDOC00931

Description

The following uncharacterized proteins have been shown [1] to share regions of similarities:

  • Yeast chromosome II hypothetical protein YBL036c.
  • Caenorhabditis elegans hypothetical protein F09E5.8.
  • Bacillus subtilis hypothetical protein ylmE.
  • Escherichia coli hypothetical protein yggS and HI0090, the corresponding Haemophilus influenzae protein.
  • Helicobacter pylori hypothetical protein HP0395.
  • Mycobacterium tuberculosis hypothetical protein MtCY270.20.
  • Synechocystis strain PCC 6803 hypothetical protein slr0556.
  • A Pseudomonas aeruginosa hypothetical protein in pilT 5'region.
  • A Vibrio alginolyticus hypothetical protein in pilT 5'region.

These are proteins of from 25 to 30 Kd which contain a number of conserved regions. As a signature pattern, we selected the best conserved region which is located in the first third of these proteins.

Last update:

December 2004 / Pattern and text revised.

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Technical section

PROSITE method (with tools and information) covered by this documentation:

UPF0001, PS01211; Uncharacterized protein family UPF0001 signature  (PATTERN)


Reference

1AuthorsBairoch A. Rudd K.E.
SourceUnpublished observations (1996).



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