We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE documentation PDOC00981Elongation factor P signature
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PURL: https://purl.expasy.org/prosite/documentation/PDOC00981
Description
Elongation factor P (EF-P) [1] is a prokaryotic protein translation factor required for efficient peptide bond synthesis on 70S ribosomes from fMet-tRNAfMet. EF-P is a protein of 21 Kd. It is evolutionary related to yeiP, an hypothetical protein from Escherichia coli.
As a signature pattern, we selected a conserved region located in the C-terminal part of these proteins.
Last update:December 2004 / Pattern and text revised.
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Technical section
PROSITE method (with tools and information) covered by this documentation:
Reference
| 1 | Authors | Aoki H. Adams S.-L. Turner M.A. Ganoza M.C. |
| Title | Molecular characterization of the prokaryotic efp gene product involved in a peptidyltransferase reaction. | |
| Source | Biochimie 79:7-11(1997). | |
| PubMed ID | 9195040 |
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