PROSITE documentation PDOC00981
Elongation factor P signature


Elongation factor P (EF-P) [1] is a prokaryotic protein translation factor required for efficient peptide bond synthesis on 70S ribosomes from fMet-tRNAfMet. EF-P is a protein of 21 Kd. It is evolutionary related to yeiP, an hypothetical protein from Escherichia coli.

As a signature pattern, we selected a conserved region located in the C-terminal part of these proteins.

Last update:

December 2004 / Pattern and text revised.


Technical section

PROSITE method (with tools and information) covered by this documentation:

EFP, PS01275; Elongation factor P signature  (PATTERN)


1AuthorsAoki H. Adams S.-L. Turner M.A. Ganoza M.C.
TitleMolecular characterization of the prokaryotic efp gene product involved in a peptidyltransferase reaction.
SourceBiochimie 79:7-11(1997).
PubMed ID9195040

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