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PROSITE documentation PDOC00982 |
Porphyromonas gingivalis collagenase (gene prtC) [1] is an enzyme that degrades type I collagen and that seems to require a metal cofactor. PrtC is evolutionary related to a number of uncharacterized proteins:
A well conserved region containing two cysteines can be used as a signature pattern for these proteins.
Note:These proteins belong to family U32 in the classification of peptidases [E1].
Last update:November 1997 / First entry.
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PROSITE method (with tools and information) covered by this documentation:
1 | Authors | Kato T. Takahashi N. Kuramitsu H.K. |
Title | Sequence analysis and characterization of the Porphyromonas gingivalis prtC gene, which expresses a novel collagenase activity. | |
Source | J. Bacteriol. 174:3889-3895(1992). | |
PubMed ID | 1317840 |
E1 | Title | https://www.uniprot.org/docs/peptidas |