|PROSITE documentation PDOC01000|
Dihydrodipicolinate reductase (EC 188.8.131.52) catalyzes the second step in the biosynthesis of diaminopimelic acid and lysine, the NAD or NADP-dependent reduction of 2,3-dihydrodipicolinate into 2,3,4,5-tetrahydrodipicolinate. This enzyme is present in bacteria (gene dapB) and higher plants.
As a signature pattern we selected the best conserved region in this enzyme. It is located in the central section and is part of the substrate-binding region .Last update:
December 2004 / Pattern and text revised.
PROSITE method (with tools and information) covered by this documentation:
|1||Authors||Scapin G. Blanchard J.S. Sacchettini J.C.|
|Title||Three-dimensional structure of Escherichia coli dihydrodipicolinate reductase.|