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PROSITE documentation PDOC01015

Prolipoprotein diacylglyceryl transferase signature





Description

Prolipoprotein diacylglyceryl transferase [1] is the bacterial enzyme that catalyzes the first step in lipoprotein biogenesis, it transfers the n-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins. Prolipoprotein diacylglyceryl transferase (gene lgt) is an integral membrane protein.

As a signature pattern for this family, we selected a highly conserved region located in the central part of the protein.

Last update:

April 2006 / Pattern revised.

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Technical section

PROSITE method (with tools and information) covered by this documentation:

LGT, PS01311; Prolipoprotein diacylglyceryl transferase signature  (PATTERN)


Reference

1AuthorsSankaran K. Wu H.C.
TitleLipid modification of bacterial prolipoprotein. Transfer of diacylglyceryl moiety from phosphatidylglycerol.
SourceJ. Biol. Chem. 269:19701-19706(1994).
PubMed ID8051048



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