PROSITE documentation PDOC50891
LOB domain profile


The LATERAL ORGAN BOUNDARIES (LOB) gene is expressed at the adaxial base of initiating lateral organs and encodes a plant-specific protein of unknown function. The N-terminal one half of the LOB protein contains a conserved approximately 100-amino acid domain (the LOB domain) that is present in 42 other Arabidopsis proteins and in proteins from a variety of other plant species. Genes encoding LOB domain (LBD) proteins are expressed in a variety of temporal- and tissue-specific patterns, suggesting that they may function in diverse processes [1].

The LOB domain contains conserved blocks of amino acids that identify the LBD gene family. In particular, a conserved C-x(2)-C-x(6)-C-x(3)-C motif, which is defining feature of the LOB domain, is present in all LBD proteins. It is possible that this motif forms a new zinc finger [1].

The profile we developed covers the entire LOB domain.

Last update:

January 2003 / First entry.


Technical section

PROSITE method (with tools and information) covered by this documentation:

LOB, PS50891; LOB domain profile  (MATRIX)


1AuthorsShuai B. Reynaga-Pena C.G. Springer P.S.
TitleThe lateral organ boundaries gene defines a novel, plant-specific gene family.
SourcePlant Physiol. 129:747-761(2002).
PubMed ID12068116

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