PROSITE documentation PDOC50891LOB domain profile
The LATERAL ORGAN BOUNDARIES (LOB) gene is expressed at the adaxial base of initiating lateral organs and encodes a plant-specific protein of unknown function. The N-terminal one half of the LOB protein contains a conserved approximately 100-amino acid domain (the LOB domain) that is present in 42 other Arabidopsis proteins and in proteins from a variety of other plant species. Genes encoding LOB domain (LBD) proteins are expressed in a variety of temporal- and tissue-specific patterns, suggesting that they may function in diverse processes [1].
The LOB domain contains conserved blocks of amino acids that identify the LBD gene family. In particular, a conserved C-x(2)-C-x(6)-C-x(3)-C motif, which is defining feature of the LOB domain, is present in all LBD proteins. It is possible that this motif forms a new zinc finger [1].
The profile we developed covers the entire LOB domain.
Last update:January 2003 / First entry.
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| 1 | Authors | Shuai B. Reynaga-Pena C.G. Springer P.S. |
| Title | The lateral organ boundaries gene defines a novel, plant-specific gene family. | |
| Source | Plant Physiol. 129:747-761(2002). | |
| PubMed ID | 12068116 | |
| DOI | 10.1104/pp.010926 |
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