Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE documentation PDOC51222DCD domain profile
View entry in original PROSITE document format
View entry in raw text format (no links)
PURL: https://purl.expasy.org/prosite/documentation/PDOC51222
The DCD domain is found in plant proteins involved in development and cell death. The DCD domain is an ~130 amino acid long stretch that contains several mostly invariable motifs. These include a FGLP and a LFL motif at the N-terminus and a PAQV and a PLxE motif towards the C-terminus of the domain. The DCD domain is present in proteins with different architectures. Some of these proteins contain additional recognizable motifs, like the KELCH repeats or the ParB domain [1].
The predicted secondary structure of the DCD domain is mostly composed of β strands and confined by an α-helix at the N- and at the C-terminus [1].
some proteins known to contain a DCD domain are listed below:
- Carrot B2 protein.
- Pea Gda-1 protein.
- Soybean N-rich protein (NRP).
The profile we developed covers the entire DCD domain.
Last update:June 2006 / First entry.
-------------------------------------------------------------------------------
PROSITE method (with tools and information) covered by this documentation:
| 1 | Authors | Tenhaken R. Doerks T. Bork P. |
| Title | DCD - a novel plant specific domain in proteins involved in development and programmed cell death. | |
| Source | BMC Bioinformatics 6:169-169(2005). | |
| PubMed ID | 16008837 | |
| DOI | 10.1186/1471-2105-6-169 |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.