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PROSITE documentation PDOC51411 |
The yeast polymerase suppressor 1 (PSP1) protein partially suppresses mutations in DNA polymerases α and delta [1]. The C-terminal half of PSP1 contains a domain, which is also found in several hypothetical proteins from both eukaryotic and prokaryotic sources:
The actual biological significance of the PSP1 C-terminal domain has not yet been clearly established.
The profile we developed covers the entire PSP1 C-terminal domain.
Last update:November 2008 / First entry.
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PROSITE method (with tools and information) covered by this documentation:
1 | Authors | Formosa T. Nittis T. |
Title | Suppressors of the temperature sensitivity of DNA polymerase alpha mutations in Saccharomyces cerevisiae. | |
Source | Mol. Gen. Genet. 257:461-468(1998). | |
PubMed ID | 9529527 |
2 | Authors | Mittra B. Ray D.S. |
Title | Presence of a poly(A) binding protein and two proteins with cell cycle-dependent phosphorylation in Crithidia fasciculata mRNA cycling sequence binding protein II. | |
Source | Eukaryot. Cell 3:1185-1197(2004). | |
PubMed ID | 15470247 | |
DOI | 10.1128/EC.3.5.1185-1197.2004 |
3 | Authors | Hosoya S. Asai K. Ogasawara N. Takeuchi M. Sato T. |
Title | Mutation in yaaT leads to significant inhibition of phosphorelay during sporulation in Bacillus subtilis. | |
Source | J. Bacteriol. 184:5545-5553(2002). | |
PubMed ID | 12270811 |