We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE documentation PDOC51519RWP-RK domain profile
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PURL: https://purl.expasy.org/prosite/documentation/PDOC51519
Description
The RWP-RK putative DNA-binding domain has been named after its most striking feature, the invariant R-W-P-x-R-K motif. It could be involved in the regulation of genes controlled by nitrogen status. The RWP-RK domain is found in the following protein [1]:
- Legume NIN (for nodule inception), a protein required for the formation of infection threads and the initiation of primordia.
- Arabidopsis NIN-like protein 1 (NLP1 or F6P23.15), a protein of unknown function.
- Arabidopsis NIN-like protein 2 (NLP2 or F23E12.170), a protein of unknown function.
- Arabidopsis NIN-like protein 7 (NLP7 or T19F6.16), a protein of unknown function.
- Arabidopsis NIN-like protein 8 (NLP8 or T1O24.24), a protein of unknown function.
- Chlamydomonas Mid, a protein that determines the development of minus gametes during gametogenesis. It controls the expression of minus-specific genes and repress the expression of the opposing plus-specific genes.
The profile we developed covers the entire RWP-RK domain.
Last update:January 2011 / First entry.
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Technical section
PROSITE method (with tools and information) covered by this documentation:
Reference
| 1 | Authors | Schauser L. Roussis A. Stiller J. Stougaard J. |
| Title | A plant regulator controlling development of symbiotic root nodules. | |
| Source | Nature 402:191-195(1999). | |
| PubMed ID | 10647012 | |
| DOI | 10.1038/46058 |
Copyright
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.