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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00033


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PURL: https://purl.expasy.org/prosite/signature/PS00033

Direct ScanProsite submission
General information about the entry

Entry name [info] ENGRAILED
Accession [info] PS00033
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-JUL-1999 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00033

Name and characterization of the entry

Description [info] 'Homeobox' engrailed-type protein signature.
Pattern [info] 
L-M-A-[EQ]-G-L-Y-N.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 24 in 24 different sequences
Number of true positive hits 24 in 24 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 96.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 24 sequences 

HME1A_DANRE (Q04896), HME1B_XENLA (P31538), HME1_CHICK  (Q05916), 

HME1_HUMAN  (Q05925), HME1_MOUSE  (P09065), HME2A_DANRE (P09015), 
HME2A_XENLA (P52729), HME2B_DANRE (P31533), HME2B_XENLA (P52730), 
HME2_CHICK  (Q05917), HME2_HUMAN  (P19622), HME2_MOUSE  (P09066), 
HME30_APIME (P09076), HME60_APIME (P09075), HMEN_ANOGA  (O02491), 
HMEN_ARTSF  (Q05640), HMEN_BOMMO  (P27609), HMEN_DROME  (P02836), 
HMEN_DROVI  (P09145), HMEN_HELTR  (P23397), HMEN_TRIGR  (P09532), 
HMIN_BOMMO  (P27610), HMIN_DROME  (P05527), SMOX2_SCHMA (Q26601)
» more

UniProtKB/Swiss-Prot
False negative sequences		 1 sequence 

HM16_CAEEL  (P34326)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			5 sequences
			


			
HME1A_XENLA (P31537), HMENA_MYXGL (P31535), HMENB_MYXGL (P31536), 

			
HMEN_LAMPL  (P31534), HMEN_SCHAM  (P14150)


			
			» more