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PROSITE entry PS00041


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PURL: https://purl.expasy.org/prosite/signature/PS00041

Direct ScanProsite submission
General information about the entry

Entry name [info] HTH_ARAC_FAMILY_1
Accession [info] PS00041
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00040

Name and characterization of the entry

Description [info] Bacterial regulatory proteins, araC family signature.
Pattern [info] 
[KRQ]-[LIVMA]-x(2)-[GSTALIV]-{FYWPGDN}-x(2)-[LIVMSA]-x(4,9)-[LIVMF]-x-
{PLH}-[LIVMSTA]-[GSTACIL]-{GPK}-{F}-x-[GANQRF]-[LIVMFY]-x(4,5)-[LFY]-
x(3)-[FYIVA]-{FYWHCM}-{PGVI}-x(2)-[GSADENQKR]-x-[NSTAPKL]-[PARL].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 330 in 328 different sequences
Number of true positive hits 221 in 219 different sequences
Number of 'unknown' hits 1
Number of false positive hits 108 in 108 different sequences
Number of false negative sequences 47
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 67.17 %
Recall (true positives / (true positives + false negatives)) 82.46 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 219 sequences 

AARP_PROST  (P43463), ADAA_BACSU  (P19219), ADA_ECOLI   (P06134), 

ADA_SALTY   (P26189), ADIY_ECOLI  (P33234), AGGR_ECOLX  (P43464), 
ALKA_MYCTO  (P9WJW2), ALKA_MYCTU  (P9WJW3), ALKR_ACIAD  (O31249), 
ANDR_BURCE  (Q84BZ4), APPY_ECOLI  (P05052), ARACL_STRAT (Q03320), 
ARACL_STRLI (P35319), ARAC_CITFR  (P11765), ARAC_DICCH  (P07642), 
ARAC_ECO57  (P0A9E1), ARAC_ECOLI  (P0A9E0), ARAC_SALTY  (P03022), 
ARGR_PSEAE  (G3XCU2), BTR_BACSU   (P40408), CAF1R_YERPE (P26950), 
CDHR_PSEAE  (Q9HTH5), CFAD_ECOLX  (P25393), CHBR_ECOLI  (P17410), 
CSVR_ECOLX  (P43460), ENVY_ECOLI  (P10805), EUTR_ECOLI  (P36547), 
EUTR_SALTY  (Q9ZFU7), EXSA_PSEAE  (P26993), FAPR_ECOLX  (P23774), 
GADW_ECO57  (P63202), GADW_ECOL6  (Q8FCI7), GADW_ECOLI  (P63201), 
GADW_SHIFL  (P63203), GADX_ECO27  (Q9EYV5), GADX_ECO57  (P58230), 
GADX_ECOL6  (Q8FCI6), GADX_ECOLI  (P37639), GADX_SHIFL  (Q83PR0), 
GBDR_PSEAB  (A0A0H2ZIC3), GBDR_PSEAE  (Q9HTI4), GLXA_RHIME  (O87389), 
HILD_SALTS  (E1WAC0), HILD_SALTY  (P0CL08), HRPB_RALN1  (P31778), 
INVF_SALTI  (P69342), INVF_SALTY  (P69343), LACR_STAXY  (O33813), 
LCRF_YERPE  (P28808), LUMQ_PHOLE  (Q51872), MARA_ECO57  (P0ACH6), 
MARA_ECOLI  (P0ACH5), MARA_SALEN  (P0A2S6), MARA_SALTI  (P0A2S5), 
MARA_SALTY  (P0A2S4), MARA_SHIFL  (P0ACH7), MELR_ECOL6  (P0ACH9), 
MELR_ECOLI  (P0ACH8), MMSR_PSEAE  (P28809), MSMR_STRMU  (Q00753), 
MXIE_SHIFL  (P0A2S7), MXIE_SHISO  (P0A2S8), NIMR_ECOLI  (P76241), 
NPHR_RHOSO  (B1Q2A8), PCHR_PSEAE  (P40883), PERA_ECO27  (P43459), 
PLH4_FORAG  (T2KMF4), POCR_SALTY  (Q05587), PQRA_PROVU  (Q52620), 
RAFR_PEDPE  (P43465), RAMA_KLEPH  (A0A0H3GPK2), RAMA_KLEPN  (Q48413), 
RAMA_SALTY  (H9L484), RHAR_CROS8  (A7ML57), RHAR_ECO24  (A7ZUB8), 
RHAR_ECO57  (Q8X7B3), RHAR_ECOBW  (C5A074), RHAR_ECOHS  (A8A710), 
RHAR_ECOK1  (A1AI83), RHAR_ECOL5  (Q0TAF7), RHAR_ECOL6  (Q8FBD7), 
RHAR_ECOLI  (P09378), RHAR_ECOUT  (Q1R413), RHAR_ENT38  (A4WG90), 
RHAR_KLEP7  (A6TGB0), RHAR_MANSM  (Q65Q30), RHAR_SALA4  (B5F0N0), 
RHAR_SALAR  (A9MI63), RHAR_SALCH  (Q57HG7), RHAR_SALDC  (B5FPP6), 
RHAR_SALEP  (B5QWY5), RHAR_SALHS  (B4TBY4), RHAR_SALNS  (B4SZZ4), 
RHAR_SALPA  (Q5PKG1), RHAR_SALPB  (A9MZC9), RHAR_SALPK  (B5BJG9), 
RHAR_SALSV  (B4TPR0), RHAR_SALTI  (Q8Z2V5), RHAR_SALTY  (P40865), 
RHAR_SHIBS  (Q31U83), RHAR_SHIDS  (Q32A71), RHAR_SHIF8  (Q0SZ96), 
RHAR_SHIFL  (Q83PD9), RHAR_YERP3  (A7FN79), RHAR_YERPA  (Q1C0W2), 
RHAR_YERPB  (B2K1W6), RHAR_YERPE  (Q8ZIZ9), RHAR_YERPG  (A9QYR6), 
RHAR_YERPN  (Q1CEB6), RHAR_YERPP  (A4TRS7), RHAR_YERPS  (Q66FF1), 
RHAR_YERPY  (B1JNC4), RHAS_CITK8  (A8AL27), RHAS_ECO24  (A7ZUB7), 
RHAS_ECO27  (B7UNM6), RHAS_ECO45  (B7MI37), RHAS_ECO55  (B7L9G1), 
RHAS_ECO57  (Q8X897), RHAS_ECO5E  (B5YZ43), RHAS_ECO7I  (B7NUA1), 
RHAS_ECO81  (B7N2P7), RHAS_ECO8A  (B7M6V7), RHAS_ECOBW  (C5A073), 
RHAS_ECODH  (B1XB72), RHAS_ECOHS  (A8A709), RHAS_ECOK1  (A1AI82), 
RHAS_ECOL5  (Q0TAF8), RHAS_ECOL6  (Q8CXW5), RHAS_ECOLC  (B1IVH3), 
RHAS_ECOLI  (P09377), RHAS_ECOLU  (B7NFK3), RHAS_ECOSE  (B6I4P8), 
RHAS_ECOSM  (B1LMU6), RHAS_ECOUT  (Q1R414), RHAS_ENT38  (A4WG91), 
RHAS_KLEP3  (B5XZ49), RHAS_KLEP7  (A6TGA9), RHAS_PECAS  (Q6DA22), 
RHAS_PECCP  (C6DJR4), RHAS_SALA4  (B5F0M9), RHAS_SALAR  (A9MI64), 
RHAS_SALCH  (Q57HG8), RHAS_SALDC  (B5FPP5), RHAS_SALEP  (B5QWY4), 
RHAS_SALG2  (B5RFC3), RHAS_SALHS  (B4TBY3), RHAS_SALNS  (B4SZZ3), 
RHAS_SALPA  (Q5PKG2), RHAS_SALPB  (A9MZC8), RHAS_SALPC  (C0Q3L4), 
RHAS_SALPK  (B5BJG8), RHAS_SALSV  (B4TPQ9), RHAS_SALTI  (P0A2T0), 
RHAS_SALTY  (P0A2S9), RHAS_SHIBS  (Q31U84), RHAS_SHIDS  (Q32A70), 
RHAS_SHIF8  (Q0SZ95), RHAS_SHIFL  (Q83PE0), RHAS_SHISS  (Q3YV71), 
RHAS_YERP3  (A7FN80), RHAS_YERPB  (B2K1W5), RHAS_YERPG  (A9QYR8), 
RHAS_YERPP  (A4TRS8), RHAS_YERPS  (Q66FF2), RHAS_YERPY  (B1JNC5), 
RIPA_CORDI  (Q6NI56), RIPA_COREF  (Q8FQS2), RIPA_CORGL  (Q8NRR3), 
RNS_ECOLX   (P16114), ROB_ECO57   (P0ACI1), ROB_ECOLI   (P0ACI0), 
ROB_SALTY   (Q8ZJU7), ROB_SHIFL   (P0ACI2), SIRC_SALTI  (Q8Z4A6), 
SIRC_SALTS  (E1WAB2), SIRC_SALTY  (P0CL09), SOXS_ECO57  (P0A9E4), 
SOXS_ECOL6  (P0A9E3), SOXS_ECOLI  (P0A9E2), SOXS_SALTY  (Q56143), 
TCPN_VIBC3  (A5F384), TCPN_VIBCH  (P0C6D6), TETD_ECOLX  (P28816), 
THCR_RHOER  (P43462), URER_ECOLX  (P32326), URER_PROMH  (Q02458), 
VIRF_SHIDY  (P0A2T2), VIRF_SHIFL  (P0A2T1), VIRF_SHISO  (P0A2T3), 
VIRF_YERE8  (A1JU91), VIRF_YEREN  (P0C2V5), XYLR_ECO57  (P0ACI5), 
XYLR_ECOL6  (P0ACI4), XYLR_ECOLI  (P0ACI3), XYLR_HAEIN  (P45043), 
XYLS1_PSEPU (Q04710), XYLS2_PSEPU (Q05092), XYLS3_PSEPU (Q05335), 
XYLS4_PSEPU (Q04713), XYLS_PSEPU  (P07859), Y1052_HAEIN (P45008), 
Y3175_SALTY (Q8ZM00), Y4FK_SINFN  (P55449), YCGK_PSEVC  (P43461), 
YDCO_ECOLI  (P76103), YDEC_BACSU  (P96660), YDEE_BACSU  (P96662), 
YDEO_ECO57  (Q8X4Z9), YDEO_ECOL6  (Q8FHG0), YDEO_ECOLI  (P76135), 
YDEO_SHIFL  (Q83RF4), YESS_BACSU  (O31522), YFIF_BACSU  (P54722), 
YIDL_ECOLI  (P31449), YIJO_ECOLI  (P32677), YISR_BACSU  (P40331), 
YMCR_STRLA  (P43458), YOBQ_BACSU  (O34901), YPDC_ECOLI  (P77396)
» more

UniProtKB/Swiss-Prot
False negative sequences		 47 sequences 

FEAR_ECOLI  (Q47129), HPTR_STAA3  (Q2FK47), HPTR_STAA8  (Q2G1E1), 

HPTR_STAAB  (Q2YV56), HPTR_STAAC  (Q5HJF7), HPTR_STAAM  (Q99X00), 
HPTR_STAAN  (Q7A7X9), HPTR_STAAR  (Q6GK93), HPTR_STAAS  (Q6GCQ3), 
HPTR_STAAW  (Q8NYJ9), MTRA_NEIGO  (Q9WW32), ORUR_PSEAE  (P72171), 
RAMA_ENTCL  (P55922), RCLR_ECOLI  (P77379), RHAR_PECAS  (Q6DA21), 
RHAR_PECCP  (C6DJR5), RHAS_ESCF3  (B7LVD8), RHAS_MANSM  (Q65Q31), 
RHAS_SHIB3  (B2TVP7), RHAS_YERPA  (Q1C0W1), RHAS_YERPE  (Q8ZJ00), 
RHAS_YERPN  (Q1CEB5), RHRA_RHIME  (Q9Z3Q6), VIRS_MYCTO  (P9WMJ2), 
VIRS_MYCTU  (P9WMJ3), VQSM_PSEAE  (Q9I1P2), Y077_STAAW  (Q8NYT6), 
Y078_STAAS  (Q6GD21), Y084_STAAC  (Q5HJR8), Y097_STAAN  (Q7A882), 
Y101_STAAM  (Q99XB1), Y107_STAAR  (Q6GKK1), Y1395_MYCTO (P9WMJ0), 
Y1395_MYCTU (P9WMJ1), Y1430_MYCBO (P68912), Y165_STAES  (Q8CQE3), 
Y1931_MYCTU (P95283), Y2406_STAEQ (Q5HKE0), YBCM_ECOLI  (P77634), 
YBFI_BACSU  (O31449), YBFP_BACSU  (O31456), YDIP_ECOLI  (P77402), 
YHTH1_STAAU (Q936F1), YKGA_ECOLI  (P77601), YNEL_ECOLI  (P76138), 
YQHC_ECOLI  (Q46855), YTDP_BACSU  (O32071)
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 1 sequence 

MRP7_CAEEL  (Q9U2G5)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			108 sequences
			


			
AAM_RHOER   (K9NBS6), ABGR_ECOLI  (P77744), AIPS_SACS2  (Q7LXU6), 

			
APY4_ARATH  (Q8H1D8), ARGD_HAEDU  (Q7VMS5), AROB_SYNP6  (Q5N3D4), 
ARSB_YEREN  (P74985), AT21A_ARATH (P0CH01), AUG1_ARATH  (F4IK01), 
BIOC_DECAR  (Q47C02), BPNT1_MOUSE (Q9Z0S1), BRE1A_ORYSI (A2XW69), 
BRE1A_ORYSJ (Q7XU27), CBID_PROM9  (Q31DE8), CHB_SERMA   (Q54468), 
CORA_YERPE  (Q8ZAG5), CORA_YERPS  (Q66FY7), ENPP1_RAT   (Q924C3), 
ERD6_ARATH  (O04036), FABD_HAEIN  (P43712), FKS3_YEAST  (Q04952), 
FTSW_ACIAD  (Q6FFC1), GATB_FRACC  (Q2J6U8), GATB_THEFY  (Q47SC0), 
GRM6_HUMAN  (O15303), GRM6_MOUSE  (Q5NCH9), GRM6_RABIT  (Q863I4), 
GRM6_RAT(P35349), HLDE_HYDCU  (Q31IC2), KDPA_PSEAE  (P57683), 
KDPA_PSEPK  (Q88FD7), KDPA_PSESM  (Q883V6), KUP1_RHIWR  (A5V2F7), 
L2_FOWPN(P15911), LYSO_ECOLI  (P75826), L_CCHFI (Q6TQR6), 
MATK_HELAN  (Q1KXX8), MEND_BACAH  (A0RK76), MEND_BACAN  (Q81K94), 
MEND_BACCN  (A7GU91), MEND_BACCR  (Q816H7), MEND_BACCZ  (Q632I2), 
MEND_BACHK  (Q6HC26), MEND_BACMK  (A9VM77), MEND_BACP2  (A8FGK9), 
MEND_BACSU  (P23970), MEND_BACVZ  (A7Z812), MEND_GEOKA  (Q5KVX6), 
MEND_GEOTN  (A4IS14), MEND_LISIN  (Q92AY5), MEND_LISMF  (Q71YZ2), 
MEND_LISMO  (Q8Y6K9), MEND_LISW6  (A0AJC9), METK_SALRD  (Q2RYY4), 
METN_CHLCV  (Q823C4), MON1_ORYSJ  (Q5JL08), MPRGB_DANRE (Q6DC77), 
MURA1_STRP1 (P65458), MURA1_STRP3 (P0DC44), MURA1_STRP6 (Q5XCX7), 
MURA1_STRP8 (P65459), MURA1_STRPM (Q48UD0), MURA1_STRPQ (P0DC45), 
MUTS_AROAE  (Q5NYP9), NAR1_LODEL  (A5DSI2), NAT12_ARATH (Q3E7D0), 
NHAA2_CLAM3 (A5CTB2), NR5A2_CHICK (O42101), NRPS8_ASPFU (Q4WVN4), 
POL2_CNSV   (Q8QVU9), POPL1_CAEEL (Q11188), PRFB3_ARATH (F4J264), 
PRP28_ASPCL (A1CHL3), PRP28_ASPFU (Q4WPE9), PRP28_ASPNC (A2QIL2), 
PRP28_ASPOR (Q2UH00), PRP28_ASPTN (Q0CLX0), PRP28_BOTFB (A6RJA2), 
PRP28_COCIM (Q1DMX8), PRP28_EMENI (Q5BCU6), PRP28_GIBZE (Q4I7F9), 
PRP28_NEOFI (A1CX72), PRP28_NEUCR (Q7SEL0), PRP28_PHANO (Q0UWC8), 
PRP28_SCLS1 (A7EGG4), PURA_ACIAD  (Q6FCS7), RH1_ARATH   (Q7FGZ2), 
RP54_VIBAN  (O08429), S2610_HUMAN (Q8NG04), S4A10_BOVIN (Q32LP4), 
S4A10_HUMAN (Q6U841), S4A10_MOUSE (Q5DTL9), S4A10_RAT   (Q80ZA5), 
SCTL_SHIFL  (Q99PY0), SELA_HAEDU  (Q7VKC2), SEM4A_HUMAN (Q9H3S1), 
SEM4B_MOUSE (Q62179), SYFB_XANAC  (Q8PJE5), SYG_MYCPA   (Q73Y21), 
SYG_NOCFA   (Q5YZT7), SYV_SCHPO   (O75005), THAQ_BURTA  (Q2T4P1), 
TLR9_BOVIN  (Q5I2M5), TLR9_SHEEP  (Q5I2M4), TM235_HUMAN (A6NFC5), 
UFL1_NEMVE  (A7S2N8), YB95_ARATH  (Q8W487), YKOC_BACSU  (O34572)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			22 PDB
			


			1BL0; 1D5Y; 1U8B; 1WPK; 1XS9; 1ZGW; 2K9S; 3GBG; 3MKL; 4FE4; 4FE7; 5SUW; 
			
				6XIU; 6XIV; 7BEF; 7BEG; 7R3W; 7VWY; 7VWZ; 7W5W; 7W5X; 7W5Y
			
			

			» more