PROSITE entry PS00046

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General information about the entry

Entry name [info] HISTONE_H2A
Accession [info] PS00046
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
PROSITE Doc. [info] PDOC00045

Name and characterization of the entry

Description [info] Histone H2A signature.
Pattern [info]

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.

Total number of hits 233 in 233 different sequences
Number of true positive hits 227 in 227 different sequences
Number of 'unknown' hits 0
Number of false positive hits 6 in 6 different sequences
Number of false negative sequences 18
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 97.42 %
Recall (true positives / (true positives + false negatives)) 92.65 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

True positive sequences
227 sequences

H2A1A_HUMAN (Q96QV6), H2A1B_HUMAN (P04908), H2A1B_MOUSE (C0HKE1), 
H2A1C_HUMAN (Q93077), H2A1C_MOUSE (C0HKE2), H2A1C_RAT   (P0C169), 
H2A1D_HUMAN (P20671), H2A1D_MOUSE (C0HKE3), H2A1E_MOUSE (C0HKE4), 
H2A1E_RAT   (P0C170), H2A1F_MOUSE (Q8CGP5), H2A1F_RAT   (Q64598), 
H2A1I_MOUSE (C0HKE6), H2A1J_HUMAN (Q99878), H2A1K_MOUSE (Q8CGP7), 
H2A1_ARATH  (Q9C681), H2A1_BOVIN  (P0C0S9), H2A1_CANAL  (Q59SU5), 
H2A1_CANGA  (Q6FWM7), H2A1_DEBHA  (Q6BKW8), H2A1_EREGS  (Q74ZL4), 
H2A1_HUMAN  (P0C0S8), H2A1_LEIIN  (P27891), H2A1_LODEL  (A5DWF1), 
H2A1_MEDTR  (Q2HU68), H2A1_ORYSI  (A2YMC5), H2A1_ORYSJ  (Q6ZL43), 
H2A1_PEA(P25470), H2A1_PICGU  (A5DBG4), H2A1_PICST  (A3LZZ0), 
H2A1_PSAMI  (P04735), H2A1_RAT(P02262), H2A1_SCHPO  (P04909), 
H2A1_SOLLC  (P25469), H2A1_TETPY  (P02274), H2A1_TETTS  (P35065), 
H2A1_WHEAT  (P02275), H2A1_XENLA  (P06897), H2A1_YEAST  (P04911), 
H2A2A_HUMAN (Q6FI13), H2A2A_MOUSE (Q6GSS7), H2A2A_RAT   (P0CC09), 
H2A2B_HUMAN (Q8IUE6), H2A2B_MOUSE (Q64522), H2A2C_BOVIN (A1A4R1), 
H2A2C_HUMAN (Q16777), H2A2C_MOUSE (Q64523), H2A2_ARATH  (Q9LHQ5), 
H2A2_CANAL  (Q59VP2), H2A2_CANGA  (Q6FM31), H2A2_DEBHA  (Q6BRG3), 
H2A2_EREGS  (Q757L4), H2A2_LEIIN  (P27892), H2A2_LODEL  (A5DXS8), 
H2A2_MEDTR  (Q2HU65), H2A2_ORYSI  (A2YMC6), H2A2_ORYSJ  (Q6ZL42), 
H2A2_PEA(P40281), H2A2_PICGU  (A5DJJ2), H2A2_PICST  (A3LXE7), 
H2A2_PSAMI  (P04736), H2A2_SCHPO  (P04910), H2A2_WHEAT  (P02276), 
H2A2_XENLA  (P06898), H2A2_YEAST  (P04912), H2A3_ARATH  (O81826), 
H2A3_CHICK  (P35062), H2A3_HUMAN  (Q7L7L0), H2A3_LYTPI  (P09589), 
H2A3_MEDTR  (Q1S053), H2A3_MOUSE  (Q8BFU2), H2A3_ORYSI  (A2YVE5), 
H2A3_ORYSJ  (Q84NJ4), H2A3_PSAMI  (P69139), H2A3_RAT(Q4FZT6), 
H2A3_STRPU  (P09590), H2A3_VOLCA  (P16865), H2A3_WHEAT  (P02277), 
H2A4_CHICK  (P02263), H2A4_ORYSI  (A2Y5G8), H2A4_ORYSJ  (Q6L500), 
H2A4_PSAMI  (P07793), H2A4_RAT(Q00728), H2A4_VOLCA  (P16866), 
H2A4_WHEAT  (Q43208), H2A5_ARATH  (Q94F49), H2A5_ORYSI  (A2WQG7), 
H2A5_ORYSJ  (Q94E96), H2A5_WHEAT  (Q43213), H2A6_ARATH  (Q9LD28), 
H2A6_ORYSI  (A2XZN0), H2A6_ORYSJ  (Q75L11), H2A6_WHEAT  (Q43214), 
H2A7_ARATH  (Q9FJE8), H2A7_ORYSI  (A2ZK29), H2A7_ORYSJ  (Q2QS71), 
H2A7_WHEAT  (Q43312), H2AE_PSAMI  (P69142), H2AJ_BOVIN  (Q3ZBX9), 
H2AJ_CHICK  (P70082), H2AJ_HUMAN  (Q9BTM1), H2AJ_MACFA  (Q4R3X5), 
H2AJ_MOUSE  (Q8R1M2), H2AJ_RAT(A9UMV8), H2AL_STRPU  (P16886), 
H2AO_CHITH  (Q07135), H2AV1_ORYSJ (Q8H7Y8), H2AV3_ARATH (Q9C944), 
H2AV3_ORYSJ (Q84MP7), H2AV_BOVIN  (Q32LA7), H2AV_CAEEL  (Q27511), 
H2AV_CHICK  (P02272), H2AV_DANRE  (Q71PD7), H2AV_DROME  (P08985), 
H2AV_HUMAN  (Q71UI9), H2AV_MOUSE  (Q3THW5), H2AV_PAGMA  (Q6Y237), 
H2AV_RABIT  (O62695), H2AV_STRPU  (P08991), H2AV_TETTS  (P08992), 
H2AV_XENLA  (Q6GM74), H2AV_XENTR  (Q5BJ65), H2AXA_ARATH (O04848), 
H2AX_DANRE  (Q7ZUY3), H2AX_HUMAN  (P16104), H2AX_MOUSE  (P27661), 
H2AX_PICAB  (P35063), H2AX_TETPY  (P02273), H2AX_TETTS  (P35064), 
H2AX_XENLA  (Q6GM86), H2AY_CAPO3  (A0A0D2UG83), H2AZL_XENLA (P70094), 
H2AZ_MOUSE  (P0C0S6), H2AZ_ONCMY  (P22647), H2AZ_PICGU  (A5DQL2), 
H2AZ_SCHPO  (P48003), H2AZ_SHEEP  (Q6YNC8), H2AZ_USTMA  (Q4PHE4), 
H2AZ_YARLI  (Q6C341), H2AZ_YEAST  (Q12692), H2A_ACIGU   (C0HJQ3), 
H2A_ACRFO   (P35061), H2A_AGABI   (Q9HGX4), H2A_ASPCL   (A1CJ10), 
H2A_ASPFU   (Q4WWC6), H2A_ASPNC   (P0C953), H2A_ASPNG   (P0C952), 
H2A_ASPOR   (Q2U5A8), H2A_ASPTN   (Q0CBD2), H2A_ASTRU   (P02269), 
H2A_BOTFB   (O74268), H2A_BUFGR   (P55897), H2A_CAEEL   (P09588), 
H2A_CAIMO   (P13912), H2A_CHAGB   (Q2HH37), H2A_CHITH   (P21896), 
H2A_CHLRE   (P50567), H2A_COCIM   (Q1E5N1), H2A_CRYNB   (P0CN99), 
H2A_CRYNJ   (P0CN98), H2A_DROER   (P84052), H2A_DROHY   (P84053), 
H2A_DROME   (P84051), H2A_DROSI   (P84054), H2A_DROYA   (P84055), 
H2A_EMENI   (P08844), H2A_EUGGR   (P40279), H2A_EUPCP   (C0HJB7), 
H2A_EUPES   (Q9M531), H2A_GIBZE   (Q4HTT1), H2A_HIPHI   (P59890), 
H2A_KLULA   (Q6CK59), H2A_MAIZE   (P40280), H2A_MYTCA   (Q6WV66), 
H2A_MYTCH   (Q6WV69), H2A_MYTED   (Q8I0T3), H2A_MYTGA   (Q6WV88), 
H2A_MYTTR   (Q6WV67), H2A_NEOFI   (A1D8G8), H2A_NEUCR   (Q8X132), 
H2A_ONCMY   (P02264), H2A_PARAN   (P69140), H2A_PARLI   (P13630), 
H2A_PENVA   (Q6PV61), H2A_PETCR   (P19177), H2A_PHANO   (Q0U1A1), 
H2A_PLADU   (P19178), H2A_PLAFA   (P40282), H2A_PODAS   (Q875B8), 
H2A_PYRO3   (L7HZV6), H2A_PYRO7   (P0CT12), H2A_RHYAM   (P84056), 
H2A_SEPOF   (P02268), H2A_SIPNU   (P02270), H2A_SPHLA   (P0DQL2), 
H2A_STRPU   (P69141), H2A_TIGCA   (P84057), H2A_TRYCR   (P35066), 
H2A_URECA   (P27325), H2A_USTMA   (Q4PEF9)
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False negative sequences
18 sequences

H2A4_ARATH  (Q9LZ46), H2A8_ORYSI  (A2ZK26), H2AB1_HUMAN (P0C5Y9), 
H2AB2_HUMAN (P0C5Z0), H2AL3_HUMAN (A0A3B3IU63), H2AV1_ARATH (O23628), 
H2AV2_ORYSJ (Q8S857), H2AV3_DICDI (Q54HV7), H2AX_DICDI  (Q54WG6), 
H2AZ_NEUCR  (Q873G4), H2A_ENCCU   (Q8SSG3), H2A_YARLI   (Q6C4I6)
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'Partial' sequences
1 sequence

H2A_OLILU   (P82897)

False positive sequences
6 sequences

CBH_CLOPE   (P54965), COXX_HYPNA  (Q0C3D1), MCD4_ASPFU  (Q4W9R7), 
NGCG_STRCO  (O50501), NU6M_ALBCA  (P48922), Y070_ANAMM  (Q5PBU4)
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[Detailed view]
564 PDB

1AOI; 1EQZ; 1F66; 1HIO; 1HQ3; 1ID3; 1KX3; 1KX4; 1KX5; 1M18; 1M19; 1M1A; 1P34; 1P3A; 1P3B; 1P3F; 1P3G; 1P3I; 1P3K; 1P3L; 1P3M; 1P3O; 1P3P; 1S32; 1TZY; 1ZBB; 1ZLA; 2ARO; 2CV5; 2F8N; 2FJ7; 2HIO; 2JSS; 2NQB; 2NZD; 2PYO; 2RVQ; 2XQL; 3A6N; 3AFA; 3AN2; 3AV1; 3AV2; 3AYW; 3AZE; 3AZF; 3AZG; 3AZH; 3AZI; 3AZJ; 3AZK; 3AZL; 3AZM; 3AZN; 3B6F; 3B6G; 3C1B; 3C1C; 3C9K; 3KUY; 3KWQ; 3LJA; 3MNN; 3O62; 3REH; 3REI; 3REJ; 3REK; 3REL; 3TU4; 3UT9; 3UTA; 3UTB; 3W96; 3W97; 3W98; 3W99; 3WA9; 3WAA; 3WKJ; 3WTP; 3X1S; 3X1V; 4CAY; 4J8U; 4J8V; 4J8W; 4J8X; 4JJN; 4KUD; 4LD9; 4M6B; 4NFT; 4QLC; 4R8P; 4WNN; 4WU8; 4WU9; 4X23; 4XUJ; 4XZQ; 4YM5; 4YM6; 4YS3; 4Z5T; 4Z66; 4ZUX; 5AV5; 5AV6; 5AV8; 5AV9; 5AVB; 5AVC; 5AY8; 5B0Y; 5B0Z; 5B1L; 5B1M; 5B24; 5B2I; 5B2J; 5B31; 5B32; 5B33; 5B40; 5BT1; 5CHL; 5CP6; 5CPI; 5CPJ; 5CPK; 5DNM; 5DNN; 5E5A; 5F99; 5FUG; 5G2E; 5GSE; 5GSU; 5GT0; 5GT3; 5GTC; 5GXQ; 5HQ2; 5JRG; 5KGF; 5MLU; 5NL0; 5O9G; 5OMX; 5ONG; 5ONW; 5OXV; 5OY7; 5WCU; 5X0X; 5X0Y; 5X7X; 5XF3; 5XF4; 5XF5; 5XF6; 5XM0; 5XM1; 5Y0C; 5Y0D; 5Z23; 5Z30; 5Z3L; 5Z3O; 5ZBX; 6A5L; 6A5O; 6A5P; 6A5R; 6A5T; 6A5U; 6AE8; 6BUZ; 6C0W; 6DZT; 6E0C; 6E0P; 6FML; 6FQ5; 6FQ6; 6FQ8; 6FTX; 6G0L; 6GEJ; 6GEN; 6HKT; 6HTS; 6I84; 6INQ; 6IPU; 6IQ4; 6IR9; 6IRO; 6IY2; 6IY3; 6J4W; 6J4X; 6J4Y; 6J4Z; 6J50; 6J51; 6JOU; 6JR0; 6JR1; 6JXD; 6K00; 6K03; 6K09; 6K0C; 6K1I; 6K1J; 6K1K; 6KBB; 6KE9; 6KIU; 6KIV; 6KIW; 6KIX; 6KIZ; 6KVD; 6KW3; 6KW4; 6KW5; 6KXV; 6L49; 6L4A; 6L9H; 6L9Z; 6LA2; 6LA8; 6LA9; 6LAB; 6LE9; 6LER; 6LTJ; 6M2M; 6M3V; 6M44; 6M4D; 6MUO; 6MUP; 6N1Z; 6NE3; 6NJ9; 6NN6; 6NOG; 6NQA; 6NZO; 6O1D; 6O96; 6OM3; 6PA7; 6PWE; 6PWF; 6PWV; 6PWW; 6PWX; 6PX1; 6PX3; 6QLD; 6R0C; 6R1T; 6R1U; 6R25; 6R8Y; 6R8Z; 6R90; 6R91; 6R92; 6R93; 6R94; 6RNY; 6RYR; 6RYU; 6S01; 6SE6; 6SEE; 6SEF; 6SEG; 6T79; 6T7A; 6T7B; 6T7C; 6T7D; 6T90; 6T93; 6T9L; 6TDA; 6TEM; 6UPH; 6UPK; 6UPL; 6USJ; 6UXW; 6V2K; 6V92; 6VEN; 6VYP; 6VZ4; 6W4L; 6W5I; 6W5M; 6W5N; 6WKR; 6WZ5; 6WZ9; 6X0N; 6X59; 6X5A; 6XJD; 6Y5D; 6Y5E; 6YOV; 6Z6P; 6ZHX; 6ZHY; 7A08; 7AT8; 7BG9; 7BP2; 7BP4; 7BP5; 7BP6; 7BWD; 7BXT; 7BY0; 7C0M; 7C7X; 7CCQ; 7CCR; 7COW; 7CRO; 7CRP; 7CRQ; 7CRR; 7D1Z; 7D20; 7DBH; 7DBP; 7DLX; 7E8D; 7E8I; 7E9C; 7E9F; 7EA8; 7EG6; 7ENN; 7JO9; 7JOA; 7JZV; 7K5X; 7K5Y; 7K60; 7K61; 7K63; 7K6P; 7K6Q; 7K78; 7K7G; 7LYA; 7LYB; 7LYC; 7M1X; 7MBM; 7MBN; 7NKX; 7NKY; 7NL0; 7OH9; 7OHA; 7OHB; 7OHC; 7ON1; 7OTQ; 7PET; 7PEU; 7PEV; 7PEW; 7PEX; 7PEY; 7PEZ; 7PF0; 7PF2; 7PF3; 7PF4; 7PF5; 7PF6; 7PFA; 7PFC; 7PFD; 7PFE; 7PFF; 7PFT; 7PFU; 7PFV; 7PFW; 7PFX; 7PII; 7PJ1; 7R5R; 7SCY; 7SCZ; 7SSA; 7SWY; 7TAN; 7TN2; 7TRF; 7U0G; 7U0I; 7U0J; 7U46; 7U47; 7U4D; 7U50; 7U51; 7U52; 7U53; 7UD5; 7UV9; 7UX9; 7V90; 7V96; 7V99; 7V9C; 7V9J; 7V9K; 7V9S; 7VA4; 7VBM; 7VCL; 7VDT; 7VDV; 7VVU; 7VVZ; 7VZ4; 7W9V; 7WBV; 7WBW; 7WBX; 7WLP; 7XCR; 7XCT; 7XD0; 7XD1; 7XFC; 7XFH; 7XFI; 7XFJ; 7XFL; 7XFM; 7XFN; 7XNP; 7XPX; 7XSE; 7XSX; 7XSZ; 7XT7; 7XTD; 7XTI; 7XVL; 7XVM; 7XX5; 7XX6; 7XX7; 7XYG; 7XZX; 7XZY; 7XZZ; 7Y00; 7Y7I; 7Y8R; 7YQK; 7YRD; 7YWX; 7YYH; 7ZI4; 7ZS9; 7ZSA; 7ZSB; 8AAG; 8ATF; 8AV6; 8B0A; 8BVW; 8BYQ; 8BZ1; 8CWW; 8CZE; 8DK5; 8DU4; 8ETT; 8EVG; 8EVH; 8EVI; 8EVJ; 8F0X; 8F1E; 8F86; 8G57; 8GPN; 8GRM; 8GRQ; 8GUI; 8GUJ; 8GUK; 8H0V; 8H0W; 8H1T; 8HAG; 8HAH; 8HAI; 8HAJ; 8HAK; 8HAL; 8HAM; 8HAN; 8HE5; 8HQY; 8HR1; 8I17; 8IEG; 8IEJ; 8JH2; 8JH3; 8JH4; 8JHF; 8JHG; 8JL9; 8JLA; 8JLB; 8JLD; 8KB5; 8OF4; 8OFF; 8OO7; 8OOA; 8OOP; 8OOS; 8OSJ; 8OSK; 8OSL; 8OTS; 8OTT; 8OW0; 8OW1; 8OX0; 8OX1; 8SIY; 8SPS; 8SPU; 8SVF; 8SYP; 8T3T; 8T3W; 8T3Y; 8T9F; 8THU; 8UX1
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