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PROSITE entry PS00069


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00069
Entry name [info] G6P_DEHYDROGENASE
Accession [info] PS00069
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00067
Associated ProRule [info] PRU10005

Name and characterization of the entry

Description [info] Glucose-6-phosphate dehydrogenase active site.
Pattern [info] 
D-H-[YF]-L-G-K-[EQK].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 67 in 67 different sequences
Number of true positive hits 67 in 67 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 6
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.10 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 6
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 67 sequences 

G6PD1_ARATH (Q43727), G6PD1_MOUSE (Q00612), G6PD1_MYCBO (P0A587), 

G6PD1_MYCTO (P9WN70), G6PD1_MYCTU (P9WN71), G6PD2_ARATH (Q9FY99), 
G6PD2_MYCBO (P0A585), G6PD2_MYCTO (P9WN72), G6PD2_MYCTU (P9WN73), 
G6PD3_ARATH (Q8L743), G6PD5_ARATH (Q9LK23), G6PD6_ARATH (Q9FJI5), 
G6PDC_SOLTU (Q43839), G6PDC_SPIOL (O24357), G6PDC_TOBAC (Q43793), 
G6PD_AGGAC  (P77809), G6PD_ASPNG  (P48826), G6PD_BACSU  (P54547), 
G6PD_BORBU  (O51581), G6PD_BOSIN  (Q7YS37), G6PD_BUCAI  (P57405), 
G6PD_BUCAP  (Q8K9M2), G6PD_BUCBP  (Q89AI7), G6PD_CAEEL  (Q27464), 
G6PD_CERCA  (P41571), G6PD_CHLMU  (Q9PKK8), G6PD_CHLPN  (Q9Z8U6), 
G6PD_CHLTR  (O84188), G6PD_CRIGR  (O55044), G6PD_CYBJA  (P11410), 
G6PD_DICD3  (P37986), G6PD_DICDI  (Q557D2), G6PD_DROME  (P12646), 
G6PD_DROYA  (Q27638), G6PD_ECO57  (Q8XCJ6), G6PD_ECOL6  (P0AC54), 
G6PD_ECOLI  (P0AC53), G6PD_EMENI  (P41764), G6PD_GLUOX  (Q5FUK8), 
G6PD_HAEIN  (P44311), G6PD_HANUV  (A0A1E5S1A9), G6PD_HELPJ  (Q9ZKB2), 
G6PD_HELPY  (P56110), G6PD_HUMAN  (P11413), G6PD_KLULA  (P48828), 
G6PD_LEUME  (P11411), G6PD_MEDSA  (Q42919), G6PD_MYCS2  (A0QP90), 
G6PD_NOSP7  (P48848), G6PD_NOSS1  (P48992), G6PD_OSPRO  (Q29492), 
G6PD_PSEAE  (O68282), G6PD_RAT(P05370), G6PD_RHIME  (Q9Z3S2), 
G6PD_SCHPO  (O00091), G6PD_SOLTU  (P37830), G6PD_STRPN  (O54537), 
G6PD_SYNE7  (P29686), G6PD_SYNY3  (P73411), G6PD_TAKRU  (P54996), 
G6PD_THEMA  (Q9X0N9), G6PD_TREPA  (O83491), G6PD_YEAST  (P11412), 
G6PD_ZYMMO  (P21907), G6PE_HUMAN  (O95479), G6PE_MOUSE  (Q8CFX1), 
G6PE_RABIT  (P56201)
» more

UniProtKB/Swiss-Prot
False negative sequences		 2 sequences 

G6PD4_ARATH (Q93ZW0), GLUPH_PLAF7 (Q8IKU0)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			6 sequences
			


			
G6PD_CULPI  (Q23711), G6PD_DIDVI  (P15588), G6PD_DROSI  (Q24625), 

			
G6PD_HYACE  (Q25019), G6PD_MAIZE  (P80619), G6PD_SARBU  (Q25537)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			35 PDB
			


			1DPG; 1E77; 1H93; 1H94; 1H9A; 1H9B; 1QKI; 2BH9; 2BHL; 2DPG; 5UKW; 6E07; 
			
				6E08; 6JYU; 6VA0; 6VA7; 6VA8; 6VA9; 6VAQ; 7E6H; 7E6I; 7SEH; 7SEI; 7SNF; 
				7SNG; 7SNH; 7TOE; 7TOF; 7UAG; 7XHL; 7XHP; 7ZVD; 8EM2; 9EMM; 9EMN
			
			

			» more