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Entry: PS00074

General information about the entry

Entry name [info] GLFV_DEHYDROGENASE
Accession [info] PS00074
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1997 DATA UPDATE;
07-APR-2021 INFO UPDATE.
PROSITE Doc. [info] PDOC00071
Associated ProRule [info] PRU10011

Name and characterization of the entry

Description [info] Glu / Leu / Phe / Val dehydrogenases active site.
Pattern [info] 
[LIV]-x(2)-G-G-[SAG]-K-x-[GV]-x(3)-[DNST]-[PL].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2021_02 which contains 564'638 sequence entries.


Total number of hits 107 in 107 different sequences
Number of true positive hits 104 in 104 different sequences
Number of 'unknown' hits 0
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 14
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 97.20 %
Recall (true positives / (true positives + false negatives)) 88.14 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 104 sequences 

DHE1_ARATH  (Q43314    ), DHE1_ORYSI  (A2XMV1    ), DHE1_ORYSJ  (Q852M0    ), 

DHE2_ARATH  (Q38946    ), DHE2_BACFR  (P94316    ), DHE2_BACSU  (P39633    ), 
DHE2_CLODI  (P27346    ), DHE2_CLOSY  (P24295    ), DHE2_HALSI  (P29051    ), 
DHE2_NEUCR  (P00365    ), DHE2_PEPAS  (P28997    ), DHE2_PORG3  (B2RKJ1    ), 
DHE2_PORGI  (P0C934    ), DHE2_SACS2  (P80053    ), DHE2_STAAC  (Q5HHC7    ), 
DHE2_STAAM  (Q99VD0    ), DHE2_STAAN  (Q7A6H8    ), DHE2_STAAR  (Q6GID0    ), 
DHE2_STAAS  (Q6GAW8    ), DHE2_STAAW  (Q7A1B9    ), DHE2_YEAST  (P33327    ), 
DHE3_AERPE  (Q9YC65    ), DHE3_ARATH  (Q9S7A0    ), DHE3_BACTN  (P94598    ), 
DHE3_BOVIN  (P00366    ), DHE3_CHICK  (P00368    ), DHE3_DICDI  (Q54KB7    ), 
DHE3_DROME  (P54385    ), DHE3_HUMAN  (P00367    ), DHE3_MAIZE  (Q43260    ), 
DHE3_MOUSE  (P26443    ), DHE3_ORYSJ  (Q6H3Y7    ), DHE3_PYRAB  (Q47950    ), 
DHE3_PYREN  (Q47951    ), DHE3_PYRFU  (P80319    ), DHE3_PYRHO  (P0CL73    ), 
DHE3_PYRHR  (P0CL72    ), DHE3_RAT    (P10860    ), DHE3_SOLLC  (P93541    ), 
DHE3_THEKO  (O59650    ), DHE3_THELN  (Q56304    ), DHE3_THEMA  (P96110    ), 
DHE3_THEPR  (O74024    ), DHE3_VITVI  (P52596    ), DHE4_AGABI  (P54387    ), 
DHE4_BOTFU  (O93934    ), DHE4_CHLSO  (P28998    ), DHE4_COREF  (Q8RQP4    ), 
DHE4_CORGL  (P31026    ), DHE4_ECOLI  (P00370    ), DHE4_EMENI  (P18819    ), 
DHE4_GIAIN  (P28724    ), DHE4_GIBFU  (Q96VJ7    ), DHE4_GORGO  (Q64I01    ), 
DHE4_HAEIN  (P43793    ), DHE4_HALSA  (Q9HRM7    ), DHE4_HALSI  (Q5MBG2    ), 
DHE4_HEBCY  (Q96UJ9    ), DHE4_HELPJ  (Q9ZKD8    ), DHE4_HELPY  (P55990    ), 
DHE4_HUMAN  (P49448    ), DHE4_HYLLA  (Q64HZ9    ), DHE4_LACBS  (P54388    ), 
DHE4_NEUCR  (P00369    ), DHE4_NEUIN  (Q9HGU4    ), DHE4_NEUSI  (Q9HGU3    ), 
DHE4_PANTR  (Q64HZ8    ), DHE4_PENCH  (Q9URS1    ), DHE4_PONPY  (Q64I00    ), 
DHE4_PRERU  (P95544    ), DHE4_PSYT1  (Q9S1F9    ), DHE4_SACSH  (P39475    ), 
DHE4_SACU7  (Q8TFF6    ), DHE4_SALTI  (Q8Z6F6    ), DHE4_SALTY  (P15111    ), 
DHE4_SCHOC  (P29507    ), DHE4_SCHPO  (P78804    ), DHE4_SYNY3  (P54386    ), 
DHE4_TUBBO  (Q9HFR6    ), DHE4_UNKP   (P14657    ), DHE4_YEAST  (P07262    ), 
DHE5_YEAST  (P39708    ), DHEB_HALSA  (P0DMG4    ), DHEB_HALSI  (P0DMG3    ), 
DHEB_NICPL  (Q9LEC8    ), DHE_HALSA   (Q9HQE1    ), DHE_HALSI   (F2Z610    ), 
DHLE_BACCE  (P0A393    ), DHLE_BACCR  (P0A392    ), DHLE_BACLI  (Q53560    ), 
DHLE_BACSU  (P54531    ), DHLE_GEOSE  (P13154    ), DHLE_THEIN  (Q60030    ), 
DHPH_BACBA  (Q59224    ), DHPH_CALTT  (F5L9G2    ), DHPH_LYSSH  (P23307    ), 
DHPH_SPOUR  (P97014    ), DHPH_THEIN  (P22823    ), GUDB_BACSU  (P50735    ), 
VDH_STRA4   (O69056    ), VDH_STRAM   (P42709    ), VDH_STRCM   (Q53872    ), 
VDH_STRCO   (Q06539    ), VDH_STRFR   (P40176    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 14 sequences 

DHE2_ACHKL  (P41755    ), DHE2_HALED  (E1V4J5    ), DHE2_MYCS2  (A0R1C2    ), 

DHE2_MYCTU  (O53203    ), DHE2_ORYSI  (A2XW22    ), DHE2_ORYSJ  (Q33E23    ), 
DHE2_PSEAE  (Q9HZE0    ), DHE2_PYRCJ  (A3MUY9    ), DHE3_CHAAC  (P82264    ), 
DHE3_SINFN  (Q53199    ), DHE4_PYRCJ  (A3MWK6    ), DHEA_NICPL  (O04937    ), 
DHPH_RHOSO  (Q59771    ), GLUD2_DICDI (Q54VI3    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 3 sequences 

DHE2_THUTH  (P20016    ), DHE3_ELEEL  (P28270    ), DHE3_PYRWO  (Q09115    )


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			3 sequences
			


			
CHM4C_DANRE (Q6IQ73    ), IRC3_YEAST  (Q06683    ), SEC24_DICDI (Q54U61    )


				
	

	

		PDB
[Detailed view]		
		
			46 PDB
			


			1AUP; 1B26; 1B3B; 1BGV; 1BVU; 1EUZ; 1GTM; 1HRD; 1HWY; 1K89; 1L1F; 1NQT; 
			
				1NR1; 1NR7; 2TMG; 2YFH; 2YFQ; 3ETD; 3ETE; 3ETG; 3JCZ; 3JD0; 3JD1; 3JD2; 
				3JD3; 3JD4; 3K8Z; 3K92; 3SBO; 4BHT; 5IJZ; 5K12; 6DHD; 6DHK; 6DHL; 6DHM; 
				6DHN; 6DHQ; 6DQG; 6G2U; 6JN9; 6JNA; 6JNC; 6JND; 6YEH; 6YEI
			
			

			» more

				
	





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