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PROSITE entry PS00074


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General information about the entry

Entry name [info] GLFV_DEHYDROGENASE
Accession [info] PS00074
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00071
Associated ProRule [info] PRU10011

Name and characterization of the entry

Description [info] Glu / Leu / Phe / Val dehydrogenases active site.
Pattern [info] 
[LIV]-x(2)-G-G-[SAG]-K-x-[GV]-x(3)-[DNST]-[PL].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.


Total number of hits 112 in 112 different sequences
Number of true positive hits 109 in 109 different sequences
Number of 'unknown' hits 0
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 14
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 97.32 %
Recall (true positives / (true positives + false negatives)) 88.62 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 109 sequences 

DHE1_ARATH  (Q43314), DHE1_ORYSI  (A2XMV1), DHE1_ORYSJ  (Q852M0), 

DHE2_ARATH  (Q38946), DHE2_BACFR  (P94316), DHE2_BACSU  (P39633), 
DHE2_CLODI  (P27346), DHE2_CLOSY  (P24295), DHE2_HALSI  (P29051), 
DHE2_NEUCR  (P00365), DHE2_PEPAS  (P28997), DHE2_PORG3  (B2RKJ1), 
DHE2_PORGI  (P0C934), DHE2_SACS2  (P80053), DHE2_STAAC  (Q5HHC7), 
DHE2_STAAM  (Q99VD0), DHE2_STAAN  (Q7A6H8), DHE2_STAAR  (Q6GID0), 
DHE2_STAAS  (Q6GAW8), DHE2_STAAW  (Q7A1B9), DHE2_YEAST  (P33327), 
DHE3_AERPE  (Q9YC65), DHE3_ARATH  (Q9S7A0), DHE3_BACTN  (P94598), 
DHE3_BOVIN  (P00366), DHE3_CHICK  (P00368), DHE3_DICDI  (Q54KB7), 
DHE3_DROME  (P54385), DHE3_HUMAN  (P00367), DHE3_MAIZE  (Q43260), 
DHE3_MOUSE  (P26443), DHE3_ORYSJ  (Q6H3Y7), DHE3_PIG(P42174), 
DHE3_PYRAB  (Q47950), DHE3_PYREN  (Q47951), DHE3_PYRFU  (P80319), 
DHE3_PYRHO  (P0CL73), DHE3_PYRHR  (P0CL72), DHE3_RAT(P10860), 
DHE3_SOLLC  (P93541), DHE3_THEKO  (O59650), DHE3_THELN  (Q56304), 
DHE3_THEMA  (P96110), DHE3_THEPR  (O74024), DHE3_VITVI  (P52596), 
DHE4_AGABI  (P54387), DHE4_BOTFU  (O93934), DHE4_CHLSO  (P28998), 
DHE4_COREF  (Q8RQP4), DHE4_CORGL  (P31026), DHE4_ECOLI  (P00370), 
DHE4_EMENI  (P18819), DHE4_GIAIN  (P28724), DHE4_GIBFU  (Q96VJ7), 
DHE4_GORGO  (Q64I01), DHE4_HAEIN  (P43793), DHE4_HALSA  (Q9HRM7), 
DHE4_HALSI  (Q5MBG2), DHE4_HEBCY  (Q96UJ9), DHE4_HELPJ  (Q9ZKD8), 
DHE4_HELPY  (P55990), DHE4_HUMAN  (P49448), DHE4_HYLLA  (Q64HZ9), 
DHE4_LACBS  (P54388), DHE4_NEUCR  (P00369), DHE4_NEUIN  (Q9HGU4), 
DHE4_NEUSI  (Q9HGU3), DHE4_PANTR  (Q64HZ8), DHE4_PENCH  (Q9URS1), 
DHE4_PONPY  (Q64I00), DHE4_PSYT1  (Q9S1F9), DHE4_SACSH  (P39475), 
DHE4_SACU7  (Q8TFF6), DHE4_SALTI  (Q8Z6F6), DHE4_SALTY  (P15111), 
DHE4_SCHOC  (P29507), DHE4_SCHPO  (P78804), DHE4_SYNY3  (P54386), 
DHE4_TUBBO  (Q9HFR6), DHE4_UNKP   (P14657), DHE4_XYLRU  (P95544), 
DHE4_YEAST  (P07262), DHE5_YEAST  (P39708), DHEB_HALSA  (P0DMG4), 
DHEB_HALSI  (P0DMG3), DHEB_NICPL  (Q9LEC8), DHE_HALSA   (Q9HQE1), 
DHE_HALSI   (F2Z610), DHLE_BACCE  (P0A393), DHLE_BACCR  (P0A392), 
DHLE_BACLI  (Q53560), DHLE_BACSU  (P54531), DHLE_GEOSE  (P13154), 
DHLE_THEIN  (Q60030), DHPH_BACBA  (Q59224), DHPH_BACTR  (A0A0F5HSE8), 
DHPH_CALTT  (F5L9G2), DHPH_LYSSH  (P23307), DHPH_RHOJR  (Q0SG95), 
DHPH_SPOUR  (P97014), DHPH_THEIN  (P22823), GUDB_BACSU  (P50735), 
TRPDH_NOSP7 (B2IXH4), TRPDH_NOSPU (W8CV45), VDH_STRA4   (O69056), 
VDH_STRAM   (P42709), VDH_STRCO   (Q06539), VDH_STRFR   (P40176), 
VDH_STRVG   (Q53872)
» more

UniProtKB/Swiss-Prot
False negative sequences		 14 sequences 

DHE2_ACHKL  (P41755), DHE2_HALED  (E1V4J5), DHE2_MYCS2  (A0R1C2), 

DHE2_MYCTU  (O53203), DHE2_ORYSI  (A2XW22), DHE2_ORYSJ  (Q33E23), 
DHE2_PSEAE  (Q9HZE0), DHE2_PYRCJ  (A3MUY9), DHE3_CHAAC  (P82264), 
DHE3_SINFN  (Q53199), DHE4_PYRCJ  (A3MWK6), DHEA_NICPL  (O04937), 
DHPH_RHOSO  (Q59771), GLUD2_DICDI (Q54VI3)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 3 sequences 

DHE2_THUTH  (P20016), DHE3_ELEEL  (P28270), DHE3_PYRWO  (Q09115)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			3 sequences
			


			
CHM4C_DANRE (Q6IQ73), IRC3_YEAST  (Q06683), SEC24_DICDI (Q54U61)


				
	

	

		PDB
[Detailed view]		
		
			80 PDB
			


			1AUP; 1B26; 1B3B; 1BGV; 1BVU; 1EUZ; 1GTM; 1HRD; 1HWY; 1K89; 1L1F; 1NQT; 
			
				1NR1; 1NR7; 2TMG; 2YFH; 2YFQ; 3ETD; 3ETE; 3ETG; 3JCZ; 3JD0; 3JD1; 3JD2; 
				3JD3; 3JD4; 3K8Z; 3K92; 3SBO; 4BHT; 5B37; 5IJZ; 5K12; 6DHD; 6DHK; 6DHL; 
				6DHM; 6DHN; 6DHQ; 6DQG; 6G2U; 6JN9; 6JNA; 6JNC; 6JND; 6YEH; 6YEI; 7MFT; 
				7UZM; 7VDA; 8EW0; 8HHO; 8HIQ; 8HIZ; 8HJ3; 8HJ9; 8KGY; 8OWM; 8OWN; 8SK8; 
				8W4J; 8XCO; 8XCP; 8XCQ; 8XCR; 8XCS; 8XCT; 8XCU; 8XCV; 8XCW; 8XCX; 8XCY; 
				8XCZ; 8XD0; 8XD1; 8XD2; 8XD3; 8XD4; 8XD5; 8XD6
			
			

			» more