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PROSITE entry PS00132


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PURL: https://purl.expasy.org/prosite/signature/PS00132

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General information about the entry

Entry name [info] CARBOXYPEPT_ZN_1
Accession [info] PS00132
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00123

Name and characterization of the entry

Description [info] Zinc carboxypeptidases, zinc-binding region 1 signature.
Pattern [info] 
[PK]-x-[LIVMFY]-x-[LIVMFY]-x(2)-{E}-x-H-[STAG]-x-E-x-[LIVM]-[STAG]-{L}-
x(5)-[LIVMFYTA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 106 in 101 different sequences
Number of true positive hits 99 in 94 different sequences
Number of 'unknown' hits 0
Number of false positive hits 7 in 7 different sequences
Number of false negative sequences 55
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 93.40 %
Recall (true positives / (true positives + false negatives)) 64.29 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] zinc at position 9
Site [info] zinc at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 94 sequences 

AEBP1_HUMAN (Q8IUX7), AEBP1_MOUSE (Q640N1), AEBP1_RAT   (A2RUV9), 

CBPA1_ANOGA (O02350), CBPA1_BOVIN (P00730), CBPA1_DROME (Q9VL86), 
CBPA1_DROPS (Q29NC4), CBPA1_HUMAN (P15085), CBPA1_MOUSE (Q7TPZ8), 
CBPA1_PIG   (P09954), CBPA1_RAT   (P00731), CBPA2_HUMAN (P48052), 
CBPA2_MOUSE (Q504N0), CBPA2_RAT   (P19222), CBPA3_MOUSE (P15089), 
CBPA3_RAT   (P21961), CBPA4_HUMAN (Q9UI42), CBPA4_MOUSE (Q6P8K8), 
CBPA5_HUMAN (Q8WXQ8), CBPA5_MACFA (Q4R7R2), CBPA5_MOUSE (Q8R4H4), 
CBPB1_BOVIN (P00732), CBPB1_CANLF (P55261), CBPB1_HUMAN (P15086), 
CBPB1_PIG   (P09955), CBPB1_RAT   (P19223), CBPB_ASTAS  (P04069), 
CBPB_HELZE  (Q3T905), CBPD_ANAPL  (Q90240), CBPD_DROME  (P42787), 
CBPD_HUMAN  (O75976), CBPD_LOPSP  (P83852), CBPD_MOUSE  (O89001), 
CBPD_RAT(Q9JHW1), CBPE_BOVIN  (P04836), CBPE_CAEEL  (O17754), 
CBPE_HUMAN  (P16870), CBPE_LOPAM  (P37892), CBPE_MACFA  (Q4R4M3), 
CBPE_MOUSE  (Q00493), CBPE_PANTR  (A5A6K7), CBPE_RAT(P15087), 
CBPM_HUMAN  (P14384), CBPM_MOUSE  (Q80V42), CBPM_PONAB  (Q5RFD6), 
CBPN_BOVIN  (Q2KJ83), CBPN_HUMAN  (P15169), CBPN_MOUSE  (Q9JJN5), 
CBPN_RAT(Q9EQV8), CBPO_BOVIN  (Q0II73), CBPO_DANRE  (B8JLQ9), 
CBPO_HUMAN  (Q8IVL8), CBPS_STRGR  (P18143), CBPS_STRMP  (P39041), 
CBPT_THEVU  (P29068), CBPZ_CHICK  (Q8QGP3), CBPZ_SIMVI  (P42788), 
CPXM1_HUMAN (Q96SM3), CPXM1_MOUSE (Q9Z100), CPXM2_HUMAN (Q8N436), 
CPXM2_MOUSE (Q9D2L5), ECM14_AJEDR (C5G6U8), ECM14_ASPCL (A1CSU3), 
ECM14_ASPFC (B0XRS8), ECM14_ASPFU (Q4X1U0), ECM14_ASPNC (A2QZA2), 
ECM14_ASPTN (Q0C9B4), ECM14_BLAGS (C5JZS0), ECM14_COCP7 (C5PHW9), 
ECM14_COCPS (E9DD69), ECM14_EMENI (Q5B011), ECM14_LEPMJ (E5A0U8), 
ECM14_NEOFI (A1DGH9), ECM14_PARBA (C1HE31), ECM14_PARBD (C1GDH9), 
ECM14_PARBP (C0SAI5), ECM14_PENRW (B6H233), ECM14_SCHPO (O74818), 
ECM14_SCLS1 (A7EUC0), ECM14_TALMQ (B6Q972), ECM14_TALSN (B8M2K0), 
ECM14_UNCRE (C4JEE1), ECM14_YEAST (P38836), ENP1_LYSSH  (Q03415), 
MCPAL_ARTBC (D4B5N0), MCPAL_ARTOC (C5FH26), MCPAL_TRIVH (D4D675), 
MCPA_ARTBC  (D4AS12), MCPA_ARTOC  (C5FVN6), MCPA_TRIEQ  (B8XGR3), 
MCPA_TRIRU  (A6XGK3), MCPA_TRITO  (B6V865), MCPA_TRIVH  (D4DL57), 
SOL1_ARATH  (Q9M9H7)
» more

UniProtKB/Swiss-Prot
False negative sequences		 55 sequences 

CBPA3_HUMAN (P15088), CBPA6_HUMAN (Q8N4T0), CBPA6_MOUSE (Q5U901), 

CBPB2_BOVIN (Q2KIG3), CBPB2_HUMAN (Q96IY4), CBPB2_MOUSE (Q9JHH6), 
CBPB2_RAT   (Q9EQV9), CBPC1_CAEEL (O76373), CBPC1_CHICK (E1C3P4), 
CBPC1_DANRE (Q4U2V3), CBPC1_HUMAN (Q9UPW5), CBPC1_MOUSE (Q641K1), 
CBPC1_XENLA (Q6DD21), CBPC1_XENTR (A9JRL3), CBPC2_DANRE (A6H8T7), 
CBPC2_HUMAN (Q5U5Z8), CBPC2_MACFA (Q4R632), CBPC2_MOUSE (Q8CDK2), 
CBPC2_XENTR (Q0P4M4), CBPC3_BOVIN (E1B9D8), CBPC3_HUMAN (Q8NEM8), 
CBPC3_MOUSE (Q8CDP0), CBPC4_HUMAN (Q96MI9), CBPC4_MOUSE (Q09M05), 
CBPC5_AILME (D2GXM8), CBPC5_BOVIN (Q58CX9), CBPC5_DANRE (Q68EI3), 
CBPC5_HUMAN (Q8NDL9), CBPC5_MOUSE (Q09M02), CBPC5_RAT   (B2GV17), 
CBPC5_XENTR (B0JZV4), CBPC6_CAEEL (Q09296), CBPC6_HUMAN (Q5VU57), 
CBPC6_MOUSE (Q09LZ8), CBPZ1_PLAF7 (Q8I2A6), CBPZ_HUMAN  (Q66K79), 
CBPZ_MOUSE  (Q8R4V4), CBPZ_RAT(O54858), ECM14_AJECG (C0NM08), 
ECM14_AJECH (C6H4F1), ECM14_AJECN (A6RCF5), ECM14_ARTBC (D4AKU7), 
ECM14_ARTGP (E4UPZ6), ECM14_ARTOC (C5FPR9), ECM14_ASPFN (B8NBP9), 
ECM14_ASPOR (Q2TZK2), ECM14_TRIVH (D4DIW7), MCPB_ARTBC  (D4B1S6), 
MCPB_ARTOC  (C5FYJ7), MCPB_TRIEQ  (B8XGR2), MCPB_TRIRU  (A6XHF7), 
MCPB_TRITO  (B6V866), MCPB_TRIVH  (D4D4Z1), NNAD_DROME  (Q9VY99), 
SURO1_CAEEL (Q9XU75)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

CBP1_SABMA  (P86516), CBPB_PROAT  (P19628)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			7 sequences
			


			
AUSK_EMENI  (C8VQ93), AUSK_PENBI  (A0A0F7TN16), BGLL_ASPTN  (Q0CEF3), 

			
SYE_ACIBC   (B2I0L0), SYE_ACIBS   (B0VPF6), SYE_ACIBY   (B0V8Q3), 
TMP_BPT5(Q6QGE7)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			119 PDB
			


			pdb_00001arl; pdb_00001arm; pdb_00001aye; pdb_00001bav; pdb_00001cbx; pdb_00001cpb; pdb_00001cps; pdb_00001cpx; pdb_00001dtd; pdb_00001ee3; pdb_00001ell; pdb_00001elm; 
			
				pdb_00001f57; pdb_00001h8l; pdb_00001hdq; pdb_00001hdu; pdb_00001hee; pdb_00001iy7; pdb_00001kwm; pdb_00001m4l; pdb_00001nsa; pdb_00001obr; pdb_00001pca; pdb_00001pyt; 
				pdb_00001qmu; pdb_00001uwy; pdb_00001yme; pdb_00001z5r; pdb_00001zg7; pdb_00001zg8; pdb_00001zg9; pdb_00001zlh; pdb_00001zli; pdb_00002abz; pdb_00002bo9; pdb_00002boa; 
				pdb_00002c1c; pdb_00002ctb; pdb_00002ctc; pdb_00002jew; pdb_00002nsm; pdb_00002pcu; pdb_00002piy; pdb_00002piz; pdb_00002pj0; pdb_00002pj1; pdb_00002pj2; pdb_00002pj3; 
				pdb_00002pj4; pdb_00002pj5; pdb_00002pj6; pdb_00002pj7; pdb_00002pj8; pdb_00002pj9; pdb_00002pja; pdb_00002pjb; pdb_00002pjc; pdb_00002rfh; pdb_00002v77; pdb_00003cpa; 
				pdb_00003fju; pdb_00003fvl; pdb_00003fx6; pdb_00003glj; pdb_00003i1u; pdb_00003kgq; pdb_00003mn8; pdb_00003prt; pdb_00003qnv; pdb_00003v38; pdb_00003v7z; pdb_00003wab; 
				pdb_00003wc5; pdb_00003wc6; pdb_00003wc7; pdb_00004a94; pdb_00004bd9; pdb_00004cpa; pdb_00004djl; pdb_00004duk; pdb_00004f8z; pdb_00004gm5; pdb_00004iav; pdb_00004ihm; 
				pdb_00004ik2; pdb_00004uee; pdb_00004uez; pdb_00004uia; pdb_00004uib; pdb_00004z65; pdb_00005cpa; pdb_00005j1q; pdb_00005jc6; pdb_00005lrg; pdb_00005lrj; pdb_00005lrk; 
				pdb_00005lyd; pdb_00005lyf; pdb_00005lyi; pdb_00005lyl; pdb_00005mrv; pdb_00005om9; pdb_00005zeq; pdb_00006cpa; pdb_00006f6q; pdb_00006f75; pdb_00006f79; pdb_00006go2; 
				pdb_00006i6z; pdb_00006sn6; pdb_00006t9y; pdb_00006tnk; pdb_00006z28; pdb_00007aqp; pdb_00007aru; pdb_00007cpa; pdb_00007q87; pdb_00008cpa; pdb_00008qvo
			
			

			» more