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| Entry: PS00136 |
General information about the entry
| Entry name [info] | SUBTILASE_ASP |
| Accession [info] | PS00136 |
| Entry type [info] | PATTERN |
| Date [info] |
01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE; 22-APR-2020 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00125 |
| Associated ProRule [info] | PRU10080 |
Name and characterization of the entry
| Description [info] | Serine proteases, subtilase family, aspartic acid active site. |
| Pattern [info] |
[STAIV]-{ERDL}-[LIVMF]-[LIVM]-D-[DSTA]-G-[LIVMFC]-x(2,3)-[DNH].
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Numerical results [info]
| Total number of hits | 354 in 354 different sequences |
| Number of true positive hits | 172 in 172 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 182 in 182 different sequences |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 6 |
| Precision (true positives / (true positives + false positives)) | 48.59 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Archaea, Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 5 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
172 sequences
AEP_YARLI (P09230 ), AEX5_CAEEL (P91863 ), ALP_ACRCH (P29118 ), ALP_FUSCU (P83610 ), ALP_HYPAT (Q03420 ), ALP_LECPS (Q68GV9 ), APRX_BACSU (O31788 ), AQL1_THEAQ (P08594 ), ASES_SARSR (R4IR27 ), ASPA_AERSA (P31339 ), BLI4_CAEEL (P51559 ), BLI_ONCVO (A0A044RE18), BPRV_DICNO (P42779 ), BPRX_DICNO (P42780 ), C5AP_STRP1 (P58099 ), C5AP_STRP3 (P0DD34 ), C5AP_STRP6 (Q5X9R0 ), C5AP_STRP8 (Q8NZ80 ), C5AP_STRPQ (P0DD35 ), C5AP_STRPY (P15926 ), CUDP_METAN (P29138 ), ELYA_BACAO (P27693 ), ELYA_BACCS (P41362 ), ELYA_BACHD (P41363 ), ELYA_BACYA (P20724 ), EPIP_STAEP (P30199 ), EXPR_XANCP (P23314 ), FKPC1_CAEEL (O17798 ), FLS_FERPE (Q93LQ6 ), FUR11_DROME (P26016 ), FUR1C_DROME (P30430 ), FUR2_DROME (P30432 ), FURI1_XENLA (P29119 ), FURIN_BOVIN (Q28193 ), FURIN_HUMAN (P09958 ), FURIN_MOUSE (P23188 ), FURIN_RAT (P23377 ), ISP1_BACSU (P11018 ), ISP6_SCHPO (P40903 ), ISP_BACCS (P29140 ), ISP_PAEPO (P29139 ), KEX1A_KLULA (P09231 ), KEX2_YEAST (P13134 ), KRP1_SCHPO (Q09175 ), MYCP2_MYCTU (O05458 ), MYCP4_MYCTU (I6YC58 ), MYCP5_MYCTU (O53945 ), NEC1_BOVIN (Q9GLR1 ), NEC1_HUMAN (P29120 ), NEC1_MOUSE (P63239 ), NEC1_MUSCO (P63240 ), NEC1_RAT (P28840 ), NEC2_BOVIN (Q9GLR0 ), NEC2_CAEEL (G5ECN9 ), NEC2_HUMAN (P16519 ), NEC2_MOUSE (P21661 ), NEC2_PIG (Q03333 ), NEC2_PONAB (Q5REC2 ), NEC2_RAT (P28841 ), NECA_HYDVU (P29146 ), NECB_HYDVU (P29145 ), NISP_LACLL (Q07596 ), NVSP_ALIVI (P83433 ), ORYZ_ASPCL (A1CIA7 ), ORYZ_ASPFC (B0Y708 ), ORYZ_ASPFN (B8N106 ), ORYZ_ASPFU (P28296 ), ORYZ_ASPOR (P12547 ), ORYZ_EMENI (Q00208 ), ORYZ_NEOFI (A1CWF3 ), P1P_LACLC (P16271 ), P2P_LACLC (P15293 ), P2P_LACPA (Q02470 ), P3P_LACLS (P15292 ), PCSK4_HUMAN (Q6UW60 ), PCSK4_MOUSE (P29121 ), PCSK4_RAT (Q78EH2 ), PCSK5_HUMAN (Q92824 ), PCSK5_MOUSE (Q04592 ), PCSK5_RAT (P41413 ), PCSK6_HUMAN (P29122 ), PCSK6_RAT (Q63415 ), PIIS_ACHLY (P81719 ), PLS_PYRFU (P72186 ), PRCA_NOSS1 (Q59149 ), PRCA_TRIV2 (P23916 ), PROA_VIBAL (P16588 ), PRTB_YEAST (P09232 ), PRTK_PARAQ (P06873 ), PRTM_BACSK (Q99405 ), PRTR_PARAQ (P23653 ), PRTT_PARAQ (P20015 ), PSP3_SCHPO (Q9UTS0 ), RM201_RHOMI (Q32ZM1 ), RRT12_YEAST (P25381 ), SBT11_ARATH (Q84WS0 ), SBT14_ARATH (Q9LVJ1 ), SBT19_ARATH (Q9FHA4 ), SBT21_ARATH (Q9SA75 ), SBT22_ARATH (Q9SUN6 ), SBT23_ARATH (Q9FI12 ), SBT24_ARATH (F4HYR6 ), SBT25_ARATH (O64481 ), SBT26_ARATH (Q9SZV5 ), SBT3G_ARATH (Q8GWX9 ), SBT4E_ARATH (Q9LLL8 ), SEPR_THESR (P80146 ), SMP1_MAGPO (Q9Y778 ), SPAZ_ARTOA (G1X8P8 ), SPAZ_ARTOL (G3FNQ9 ), SPL1_ENCCU (Q8SQJ3 ), SUB10_ARTBC (D4AQG0 ), SUB10_TRIVH (D4DIS6 ), SUB1_PSED2 (L8G6I7 ), SUB2A_COCP7 (C5P6D1 ), SUB2B_COCP7 (C5P906 ), SUB2C_COCP7 (C5NZ70 ), SUB2_ARTBC (D4AZ75 ), SUB2_ARTBE (Q64K35 ), SUB2_ARTGP (E4UZP9 ), SUB2_ARTOC (C5G168 ), SUB2_ARTOT (Q8J0D8 ), SUB2_PSED2 (L8FSM5 ), SUB2_TRIEQ (B6VA85 ), SUB2_TRIRU (Q69F57 ), SUB2_TRITO (B8XGQ5 ), SUB2_TRIVC (Q5VJ76 ), SUB2_TRIVH (D4DLI5 ), SUB3_PSED2 (L8GD75 ), SUB4B_COCP7 (C5NZT2 ), SUB5_ARTBC (D4B194 ), SUB5_ARTBE (Q64K32 ), SUB5_ARTGP (E4V2L6 ), SUB5_ARTOC (C5G1D1 ), SUB5_TRIEQ (B6VA87 ), SUB5_TRIRU (Q69F34 ), SUB5_TRITO (B8XGQ8 ), SUB5_TRIVC (Q5VJ73 ), SUB5_TRIVH (D4D0F5 ), SUB6_ARTBC (D4ALV9 ), SUB6_ARTBE (Q64K31 ), SUB6_ARTGP (E4V4J8 ), SUB6_ARTOC (C5FQI3 ), SUB6_TRIEQ (A1XIH0 ), SUB6_TRIRU (Q9UW97 ), SUB6_TRISD (A1XIH1 ), SUB6_TRISH (Q8J077 ), SUB6_TRITO (Q3ZEJ8 ), SUB6_TRIVC (Q5VJ72 ), SUB6_TRIVH (D4D5H3 ), SUB7A_COCP7 (C5PGK9 ), SUB7C_COCP7 (C5NZ69 ), SUB7D_COCP7 (C5P9H3 ), SUBB_BACLE (P29599 ), SUBC_BACLI (P00780 ), SUBD_BACLI (P00781 ), SUBE_BACSU (P16396 ), SUBN_BACNA (P35835 ), SUBS_BACLE (P29600 ), SUBT_BACAM (P00782 ), SUBT_BACPU (P07518 ), SUBT_BACS9 (P28842 ), SUBT_BACSA (P00783 ), SUBT_BACSU (P04189 ), SUBT_GEOSE (P29142 ), SUBV_BACSU (P29141 ), THES_BACSJ (Q45670 ), THET_THEVU (P04072 ), TKSP_THEKO (Q5JIZ5 ), TKSU_THEKO (P58502 ), XPR6_YARLI (P42781 ), YSP3_YEAST (P25036 )» more
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| UniProtKB/Swiss-Prot 'Partial' sequences |
6 sequences
ASE2_ACRSP (P85157 ), CUDP_METCM (P80406 ), NCP3_COPCM (P83454 ), PRTE_HALME (P28308 ), SP01_SCEBO (Q10721 ), THEM_MALCI (P13858 )» more |
| UniProtKB/Swiss-Prot False positive sequences |
182 sequences
ACDA1_ARCFU (O29165 ), AGLU_TETPY (O00906 ), ALDO3_ARATH (Q7G9P4 ), AP1_KLULA (P56095 ), ARGC_CHRVO (Q7NRT5 ), BAH_RHOER (Q8RSQ2 ), BTUB_PHOLL (Q7MYE3 ), CBID_PROMP (Q7V3N8 ), CHS1_CRYNH (O13356 ), CLS2_STAAC (Q5HEB2 ), CLS2_STAAR (Q6GEY7 ), CLS_STAAM (P63800 ), CLS_STAAN (P63801 ), CLS_STAAS (Q6G7M2 ), CLS_STAAW (P63802 ), COBT_DEIRA (Q9RYR8 ), DCL4_ORYSJ (A7LFZ6 ), DMXL1_HUMAN (Q9Y485 ), DMXL1_MOUSE (Q6PNC0 ), DNAG_NEIMA (P57028 ), DNAG_NEIMB (P57029 ), DNLJ1_STRGG (B1VUC2 ), DNLJ_FERNB (A7HJG6 ), DRD1_CARAU (P35406 ), EXOC1_DICDI (Q54NV1 ), FIXJ_AZOC5 (P26487 ), FLII_BUCBP (Q89AZ7 ), FMT_GEOSL (Q74GW4 ), FOLD2_ACIAD (Q6F8N7 ), FOLD_ACIBT (A3M846 ), FOLD_CALS4 (Q8RAD0 ), FOLD_MYCPE (Q8EV80 ), FOLD_PSYA2 (Q4FTX6 ), FOLD_PSYCK (Q1QD30 ), FOLD_RUTMC (A1AXA0 ), GLUQ_CUTAK (Q6A7Y1 ), GLYA_CUTAK (Q6AAU3 ), GLYA_MYCS2 (A0R2V7 ), GUAAB_PICTO (Q6L1Q1 ), GUAA_ASPOR (Q2UFN0 ), HEM1_RHORT (Q2RWE2 ), HIS5_ECOL6 (P60596 ), HIS5_ECOLI (P60595 ), HIS5_SHIBS (Q323I9 ), HIS5_SHIDS (Q32EF2 ), HIS5_SHIFL (Q83KJ5 ), HIS5_SHISS (Q3Z0G2 ), HLYE_ECO57 (Q9REB3 ), HLYE_ECOLI (P77335 ), HN1BA_DANRE (A1L1N5 ), HN1BB_DANRE (Q8UW00 ), HOA_PARPJ (B2T2S2 ), HOY1_YARLI (Q99160 ), KATG2_ALKMQ (A6TV07 ), KATG_PHEZH (B4R8U3 ), KATG_SACD2 (Q21DT6 ), KUP3_RHIL3 (Q1M651 ), LCAP_HUMAN (Q9UIQ6 ), LEC2_CYTSE (P22971 ), LEU3_BRUA2 (Q2YL58 ), LEU3_BRUAB (Q579B1 ), LEU3_BRUME (Q8YCX4 ), LEU3_BRUSU (Q8FVF3 ), LPXK_HELAH (Q17X64 ), LPXK_HELPH (Q1CUH3 ), LPXK_HELPJ (Q9ZMB1 ), LPXK_HELPY (O25095 ), LRC14_BOVIN (A5PJJ5 ), LRC14_HUMAN (Q15048 ), LRC14_MOUSE (Q8VC16 ), LRC14_RAT (Q569B5 ), LRRC3_DANRE (A8WHP9 ), MATK_GAGLU (Q9TMC8 ), MATK_ILLOL (A6MMS5 ), METL2_ARATH (Q8LFA9 ), METN1_PSEU2 (Q4ZZR8 ), MSTO1_BOVIN (A5D9D4 ), MSTO1_HUMAN (Q9BUK6 ), MSTO1_MACFA (Q4R681 ), MSTO1_MOUSE (Q2YDW2 ), MSTO1_PONPY (Q5RF82 ), MYO2_CAEEL (P12845 ), MZT1B_ARATH (Q9M0N8 ), NADE_SHEON (Q8EFF2 ), NADO2_ORYSJ (Q7G765 ), NCAP_CVM1 (P18446 ), NCAP_CVM2 (Q9PY96 ), NCAP_CVM3 (P18447 ), NCAP_CVMA5 (P03416 ), NCAP_CVMDV (Q83360 ), NCAP_CVMJH (P03417 ), NCAP_CVMS (P18448 ), NCAP_CVPV (P59713 ), NCAP_CVRNJ (Q9WCD0 ), NCAP_CVRSD (Q02915 ), NEMS_APIME (P85527 ), NOL6_DROME (Q8IH00 ), NOL6_DROSE (B4IBY3 ), NOL6_DROSI (B4QX57 ), NOL6_DROYA (B4PR18 ), NR2C1_BOVIN (A0JNE3 ), NR2C1_HUMAN (P13056 ), NR2C1_MACFA (Q95K90 ), NR2C1_MOUSE (Q505F1 ), NR2C1_PONAB (Q5RCZ5 ), NR2C1_RAT (Q8VIJ4 ), NR2C1_XENTR (Q28CK1 ), NUS1_ASPOR (P24021 ), OGR1_ORYSJ (B8YEK4 ), PA24A_BOVIN (A4IFJ5 ), PA24A_CHICK (P49147 ), PA24A_DANRE (P50392 ), PA24A_HORSE (O77793 ), PA24A_HUMAN (P47712 ), PA24A_MOUSE (P47713 ), PA24A_PONAB (Q5R8A5 ), PA24A_RABIT (Q9TT38 ), PA24A_RAT (P50393 ), PA24A_XENLA (Q7T0T9 ), PA24A_XENTR (B1WAZ6 ), PDAD_METKA (Q8TXD4 ), PEPQ_AERHH (A0KEL3 ), PEPQ_AERS4 (A4STF0 ), PGP_ARCFU (O29805 ), PNP_FRAT1 (Q14IC9 ), PNP_FRATF (A7NDP3 ), PNP_FRATH (Q2A269 ), PNP_FRATM (B2SDK7 ), PNP_FRATN (A0Q5I9 ), PNP_FRATO (Q0BKU1 ), PNP_FRATT (Q5NGX7 ), PNP_FRATW (A4IZA6 ), PP263_ARATH (Q9M2A1 ), PPOC_ARATH (P55826 ), PURA_LEIDO (A7LBL2 ), PURA_LEIIN (A4HVP7 ), PURA_LEIMA (Q4QG35 ), PYRE_PHOLL (Q7MY25 ), PYRE_SHEON (Q8E9L5 ), PYRE_VIBCH (Q9KVD5 ), RNJ1_STAA3 (Q2FHZ1 ), RNJ1_STAA8 (Q2FZG9 ), RNJ1_STAAB (Q2YX35 ), RNJ1_STAAC (Q5HGZ5 ), RNJ1_STAAM (Q99V09 ), RNJ1_STAAN (Q7A682 ), RNJ1_STAAR (Q6GHZ6 ), RNJ1_STAAS (Q6GAC5 ), RNJ1_STAAW (Q7A171 ), RNJ1_STAEQ (Q5HQ80 ), RNJ1_STAES (Q8CT16 ), RNJ1_STAHJ (Q4L5A3 ), RNJ1_STAS1 (Q49WL3 ), RPOB_KORVE (Q1IHH4 ), RR2_THAPS (A0T0Q8 ), SC6_SCHCO (O74300 ), SECA_MYCPU (Q98RA6 ), SEY1_SCHPO (Q9UTE0 ), SMI1_SCHPO (O14362 ), STE13_YEAST (P33894 ), SYFB_THIDA (Q3SK29 ), T2S1_LACLC (O34104 ), TEN1_HUMAN (Q9UKZ4 ), TEN1_MOUSE (Q9WTS4 ), TRP3_ARATH (Q9C7B1 ), VL2_HPV42 (P27235 ), XERS_LACLA (Q9CG78 ), XERS_LACLM (A2RKP9 ), XERS_LACLS (Q02YZ4 ), XOL1_CAEEL (Q23229 ), Y072_CHLTR (O84075 ), Y1273_MYCTU (P9WQJ1 ), Y1304_MYCBO (P0A4W5 ), Y1776_COREF (Q8FPK2 ), Y344_CHLMU (Q9PKW7 ), Y4KK_SINFN (P55529 ), Y5194_MYCGI (A4T1E2 ), Y973_METJA (Q58383 ), YFIB_BACSU (P54718 ), YQ02_CAEEL (Q17405 ), YSH1_ASHGO (Q74ZC0 ), YSH1_YARLI (Q6C2Z7 )» more |
| PDB [Detailed view] |
281 PDB
1A2Q; 1AF4; 1AH2; 1AK9; 1AQN; 1AU9; 1AV7; 1AVT; 1BE6; 1BE8; 1BFK; 1BFU; 1BH6; 1BJR; 1C3L; 1C9J; 1C9M; 1C9N; 1CNM; 1CSE; 1DBI; 1DUI; 1EGQ; 1GCI; 1GNS; 1GNV; 1HT3; 1IAV; 1IC6; 1JEA; 1LW6; 1MEE; 1MPT; 1NDQ; 1NDU; 1OT5; 1OYO; 1OYV; 1P7V; 1P7W; 1P8J; 1PEK; 1PFG; 1PJ8; 1PTK; 1Q5P; 1R0R; 1R64; 1R6V; 1S01; 1S02; 1SBC; 1SBH; 1SBI; 1SBN; 1SBT; 1SCA; 1SCB; 1SCD; 1SCJ; 1SCN; 1SEL; 1SIB; 1ST2; 1ST3; 1SUA; 1SUB; 1SUC; 1SUD; 1SUE; 1SUP; 1SVN; 1TEC; 1THM; 1TK2; 1TM1; 1TM3; 1TM4; 1TM5; 1TM7; 1TMG; 1TO1; 1TO2; 1UBN; 1V5I; 1VSB; 1WSD; 1XF1; 1Y1K; 1Y33; 1Y34; 1Y3B; 1Y3C; 1Y3D; 1Y3F; 1Y48; 1Y4A; 1Y4D; 1YJA; 1YJB; 1YJC; 1YU6; 2DP4; 2DQK; 2DUJ; 2E1P; 2G4V; 2HD4; 2HPZ; 2ID4; 2ID8; 2PKC; 2PQ2; 2PRK; 2PWA; 2PWB; 2PYZ; 2SBT; 2SEC; 2SIC; 2SNI; 2ST1; 2TEC; 2V8B; 2WUV; 2WUW; 2Z2X; 2Z2Y; 2Z2Z; 2Z30; 2Z56; 2Z57; 2Z58; 2ZRQ; 2ZWO; 2ZWP; 3A3N; 3A3O; 3A3P; 3AFG; 3AJ8; 3AJ9; 3BX1; 3D9Q; 3DDZ; 3DE0; 3DE1; 3DE2; 3DE3; 3DE4; 3DE5; 3DE6; 3DE7; 3DVQ; 3DVR; 3DVS; 3DW1; 3DW3; 3DWE; 3DYB; 3EIF; 3F7M; 3GT3; 3GT4; 3I2Y; 3I30; 3I34; 3I37; 3L1K; 3OSZ; 3PRK; 3PTL; 3Q40; 3Q5G; 3QMP; 3SIC; 3TEC; 3UNX; 3VHQ; 3VSB; 3VV2; 3VYV; 3WHI; 3WIU; 3WIV; 4B5L; 4C3U; 4C3V; 4CFY; 4CFZ; 4CG0; 4DJ5; 4DWW; 4DZT; 4FON; 4JP8; 4MZD; 4OMC; 4OMD; 4RYD; 4WOB; 4WOC; 4Z2A; 4ZAR; 5AMX; 5AQE; 5ARB; 5ARC; 5ARD; 5AVJ; 5AVK; 5B1D; 5B1E; 5CW1; 5GL8; 5I9S; 5JMO; 5JXG; 5JXH; 5JXI; 5JXJ; 5K7S; 5KXU; 5KXV; 5MIM; 5MJL; 5OX2; 5SIC; 5UVL; 5WHW; 5WJG; 5WJH; 5WRC; 6CL7; 6CL8; 6CL9; 6CLA; 6CLB; 6DWQ; 6EQV; 6EQW; 6EQX; 6FJS; 6HLB; 6HLD; 6HLE; 6HZA; 6HZB; 6HZC; 6HZD; 6J43; 6K8M; 6KKF; 6LAW; 6MH6; 6N4U; 6O44; 6PAK; 6PKJ; 6PKK; 6PKL; 6PKM; 6PKN; 6PKO; 6PKP; 6PKQ; 6PKR; 6PKS; 6PKT; 6PU4; 6PU5; 6QF1; 6QXV; 6RUG; 6RUH; 6RUK; 6RUN; 6RUW; 6RVE; 6RVG; 6RZP » more |
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