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PROSITE entry PS00140


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General information about the entry

Entry name [info] UCH_1
Accession [info] PS00140
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00127
Associated ProRule [info] PRU10091

Name and characterization of the entry

Description [info] Ubiquitin carboxyl-terminal hydrolase family 1 cysteine active-site.
Pattern [info]
Q-x(3)-N-[SA]-C-G-x(3)-[LIVM](2)-H-[SA]-[LIVM]-[SA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 17 in 17 different sequences
Number of true positive hits 17 in 17 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 29
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 36.96 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] active_site at position 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
17 sequences

UBL1_YEAST  (P35127), UBLH1_SCHPO (Q10171), UCHL1_BOVIN (P23356), 
UCHL1_HORSE (Q9GM50), UCHL1_HUMAN (P09936), UCHL1_MACFA (Q60HC8), 
UCHL1_MONDO (P50103), UCHL1_MOUSE (Q9R0P9), UCHL1_PIG   (Q6SEG5), 
UCHL1_RAT   (Q00981), UCHL3_BOVIN (Q2TBG8), UCHL3_HUMAN (P15374), 
UCHL3_MOUSE (Q9JKB1), UCHL3_PIG   (Q06AB3), UCHL3_RAT   (Q91Y78), 
UCHL_APLCA  (O01391), UCHL_DROME  (P35122)
» more

UniProtKB/Swiss-Prot
False negative sequences
29 sequences

BAP1_BOVIN  (A2VDM8), BAP1_BRAFL  (C4A0D9), BAP1_CHICK  (Q5F3N6), 
BAP1_DANRE  (A1L2G3), BAP1_HUMAN  (Q92560), BAP1_MOUSE  (Q99PU7), 
BAP1_RAT(D3ZHS6), BAP1_XENLA  (Q52L14), BAP1_XENTR  (Q66JB6), 
CALYP_AEDAE (Q17N72), CALYP_CULQU (B0W2R4), CALYP_DROAN (B3MIV9), 
CALYP_DROER (B3NPV7), CALYP_DROGR (B4JW98), CALYP_DROME (Q7K5N4), 
CALYP_DROMO (B4KT51), CALYP_DROPE (B4GAM2), CALYP_DROPS (Q291J4), 
CALYP_DROSE (B4HST0), CALYP_DROSI (B4QHH0), CALYP_DROVI (B4LQ24), 
CALYP_DROYA (B4P6P6), UBH4_CAEEL  (Q09444), UBLH2_SCHPO (Q9UUB6), 
UCHL4_MOUSE (P58321), UCHL5_BOVIN (Q9XSJ0), UCHL5_DICDI (Q54N38), 
UCHL5_HUMAN (Q9Y5K5), UCHL5_MOUSE (Q9WUP7)
» more

PDB
[Detailed view]
19 PDB

1CMX; 1UCH; 1XD3; 2ETL; 2LEN; 3IFW; 3IRT; 3KVF; 3KW5; 4DM9; 4JKJ; 6ISU; 6QML; 7EN4; 7YV4; 7ZM0; 8DY8; 8EDE; 8PW1
» more