PROSITE entry PS00143
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General information about the entry
| Entry name [info] | INSULINASE |
| Accession [info] | PS00143 |
| Entry type [info] | PATTERN |
| Date [info] |
01-APR-1990 CREATED;
01-NOV-1997 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00130 |
| Associated ProRule [info] | PRU10096 |
Name and characterization of the entry
| Description [info] | Insulinase family, zinc-binding region signature. |
| Pattern [info] |
G-x(8,9)-G-x-[STA]-H-[LIVMFY]-[LIVMC]-[DERN]-[HRKL]-[LMFAT]-x-[LFSTH]-x- [GSTAN]-[GST]. |
Numerical results [info]
| Total number of hits | 75 in 75 different sequences |
| Number of true positive hits | 75 in 75 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 40 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 65.22 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Site [info] | zinc at position 6 |
| Site [info] | active_site at position 9 |
| Site [info] | zinc at position 10 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
75 sequences
AXL1_YEAST (P40851), IDE1_ARATH (O22941), IDE2_ARATH (F4J3D9), IDE_BOVIN (Q24K02), IDE_DICDI (Q54JQ2), IDE_DROME (P22817), IDE_HUMAN (P14735), IDE_MOUSE (Q9JHR7), IDE_RAT (P35559), MPPA1_ARATH (Q9ZU25), MPPA2_ARATH (O04308), MPPA_BOVIN (Q0P5M8), MPPA_HUMAN (Q10713), MPPA_MOUSE (Q9DC61), MPPA_NEUCR (P23955), MPPA_PONAB (Q5R513), MPPA_RAT(P20069), MPPA_SCHPO (O94745), MPPA_SOLTU (P29677), MPPA_YEAST (P11914), MPPB_ARATH (Q42290), MPPB_BOVIN (Q3SZ71), MPPB_CAEEL (Q23295), MPPB_DICDI (Q4W6B5), MPPB_HUMAN (O75439), MPPB_LENED (Q9Y8B5), MPPB_MOUSE (Q9CXT8), MPPB_NEUCR (P11913), MPPB_PONAB (Q5REK3), MPPB_RAT(Q03346), MPPB_SCHPO (Q9P7X1), MPPB_YEAST (P10507), MU138_SCHPO (O14077), NRDC_ARATH (F4HNU6), NRDC_HUMAN (O43847), NRDC_MOUSE (Q8BHG1), NRDC_PONAB (Q5R4H6), NRDC_RAT(P47245), PPQQE_HELPY (O25656), PQQF_KLEPN (P27508), PQQF_PSEAE (Q9I2D2), PQQF_PSEPH (P55174), PQQF_PSEPK (Q88QV3), PQQF_PSESM (Q88A79), PQQL_ARATH (Q9FJT9), PQQL_ECOLI (P31828), PQQL_HAEIN (P45181), PTRA_ECO57 (Q8X6M8), PTRA_ECOL6 (Q8CVS2), PTRA_ECOLI (P05458), PTRA_SALTY (Q8ZMB5), PTRA_SHIFL (Q83QC3), QCR1_EUGGR (P43264), QCR2_BOVIN (P23004), QCR2_HUMAN (P22695), QCR2_MOUSE (Q9DB77), QCR2_RAT(P32551), QCR2_YARLI (Q6C2E3), QCR2_YEAST (P07257), SDP_EIMBO (P42789), STE23_YEAST (Q06010), UCR1_CAEEL (P98080), Y210_RICTY (Q68XF0), Y219_RICPR (O05945), Y2782_MYCTO (P9WHT4), Y2782_MYCTU (P9WHT5), Y2805_MYCBO (P0A5S9), Y293_RICCN (Q92IX7), Y338_RICFE (Q4UML9), Y4WA_SINFN (P55679), Y522_RICBR (Q1RJ61), Y5738_STRCO (O86835), Y855_MYCLE (O32965), YMXG_BACSU (Q04805), YQA4_CAEEL (Q10040)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
40 sequences
ALBF_BACIU (Q8RKH2), ALBF_BACSU (P71006), MPPA_BLAEM (P97997), PREP1_ARATH (Q9LJL3), PREP2_ARATH (Q8VY06), PREP_ASPFU (Q4WP38), PREP_ASPOR (Q2UGN1), PREP_CANAL (Q5A301), PREP_CANGA (Q6FUI7), PREP_DANRE (Q7ZVZ6), PREP_DEBHA (Q6BTC0), PREP_DROME (Q9V9E3), PREP_EMENI (Q5B6H7), PREP_EREGS (Q759T9), PREP_GIBZE (Q4IA56), PREP_HUMAN (Q5JRX3), PREP_KLULA (Q6CWW6), PREP_MOUSE (Q8K411), PREP_NEUCR (Q7S7C0), PREP_PONAB (Q5RDG3), PREP_SCHPO (O42908), PREP_XENLA (Q6PF24), PREP_XENTR (Q28BR5), PREP_YARLI (Q6C0U8), PREP_YEAST (P32898), PTRA_SALTI (Q8Z418), QCR1_BOVIN (P31800), QCR1_HUMAN (P31930), QCR1_MOUSE (Q9CZ13), QCR1_YEAST (P07256), QCR2_EUGGR (P43265), SPP_ARATH (Q9FIH8), SPP_ORYSI (B8B0E2), SPP_ORYSJ (Q69TY5), SPP_PEA (Q40983), Y4WB_SINFN (P55680), YHJJ_ECOLI (P37648), YHJJ_SALTI (Q8Z286), YHJJ_SALTY (P50335), YMFH_BACSU (O31766)» more |
| PDB [Detailed view] |
129 PDB
1BCC; 1BE3; 1BGY; 1EZV; 1HR6; 1HR7; 1HR8; 1HR9; 1KB9; 1KYO; 1L0L; 1L0N; 1NTK; 1NTM; 1NTZ; 1NU1; 1P84; 1PP9; 1PPJ; 1Q2L; 1QCR; 1SQB; 1SQP; 1SQQ; 1SQV; 1SQX; 2A06; 2BCC; 2FYU; 2IBZ; 2JG4; 2YBB; 3BCC; 3CX5; 3CXH; 3P7L; 3QZ2; 3TUV; 4D6T; 4D6U; 4DTT; 4IFH; 4IOF; 4PD4; 4RE9; 5GPN; 5KLV; 5LUF; 5NMI; 5OKD; 5UOE; 5XTE; 5XTH; 5XTI; 6B3Q; 6B70; 6B7Y; 6B7Z; 6BF6; 6BF7; 6BF8; 6BF9; 6BFC; 6FO0; 6FO2; 6FO6; 6GIQ; 6HAW; 6HU9; 6NHG; 6OFS; 6OFT; 6T0B; 6T15; 6XVF; 6YMX; 6ZFS; 6ZFT; 6ZFU; 7DGQ; 7DGR; 7DGS; 7DKF; 7K1D; 7K1E; 7K1F; 7O37; 7O3C; 7O3E; 7O3H; 7R3V; 7RZE; 7RZF; 7RZG; 7RZH; 7RZI; 7TAY; 7TZ6; 8AB6; 8AB7; 8AB8; 8AB9; 8ABA; 8ABB; 8ABE; 8ABF; 8ABG; 8ABH; 8ABI; 8ABJ; 8ABK; 8ABL; 8ABM; 8AC3; 8AC4; 8AC5; 8BEP; 8BPX; 8BQ5; 8BQ6; 8E7S; 8EC0; 8IUF; 8IUJ; 8P65; 8PW5; 8PW6; 8PW7; 8Q1B » more |