PROSITE entry PS00143
View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry
| Entry name [info] | INSULINASE |
| Accession [info] | PS00143 |
| Entry type [info] | PATTERN |
| Date [info] |
01-APR-1990 CREATED;
01-NOV-1997 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00130 |
| Associated ProRule [info] | PRU10096 |
Name and characterization of the entry
| Description [info] | Insulinase family, zinc-binding region signature. |
| Pattern [info] |
G-x(8,9)-G-x-[STA]-H-[LIVMFY]-[LIVMC]-[DERN]-[HRKL]-[LMFAT]-x-[LFSTH]-x- [GSTAN]-[GST]. |
Numerical results [info]
| Total number of hits | 75 in 75 different sequences |
| Number of true positive hits | 75 in 75 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 40 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 65.22 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Site [info] | zinc at position 6 |
| Site [info] | active_site at position 9 |
| Site [info] | zinc at position 10 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
75 sequences
AXL1_YEAST (P40851), IDE1_ARATH (O22941), IDE2_ARATH (F4J3D9), IDE_BOVIN (Q24K02), IDE_DICDI (Q54JQ2), IDE_DROME (P22817), IDE_HUMAN (P14735), IDE_MOUSE (Q9JHR7), IDE_RAT (P35559), MPPA1_ARATH (Q9ZU25), MPPA2_ARATH (O04308), MPPA_BOVIN (Q0P5M8), MPPA_HUMAN (Q10713), MPPA_MOUSE (Q9DC61), MPPA_NEUCR (P23955), MPPA_PONAB (Q5R513), MPPA_RAT(P20069), MPPA_SCHPO (O94745), MPPA_SOLTU (P29677), MPPA_YEAST (P11914), MPPB_ARATH (Q42290), MPPB_BOVIN (Q3SZ71), MPPB_CAEEL (Q23295), MPPB_DICDI (Q4W6B5), MPPB_HUMAN (O75439), MPPB_LENED (Q9Y8B5), MPPB_MOUSE (Q9CXT8), MPPB_NEUCR (P11913), MPPB_PONAB (Q5REK3), MPPB_RAT(Q03346), MPPB_SCHPO (Q9P7X1), MPPB_YEAST (P10507), MU138_SCHPO (O14077), NRDC_ARATH (F4HNU6), NRDC_HUMAN (O43847), NRDC_MOUSE (Q8BHG1), NRDC_PONAB (Q5R4H6), NRDC_RAT(P47245), PPQQE_HELPY (O25656), PQQF_KLEPN (P27508), PQQF_PSEAE (Q9I2D2), PQQF_PSEPH (P55174), PQQF_PSEPK (Q88QV3), PQQF_PSESM (Q88A79), PQQL_ARATH (Q9FJT9), PQQL_ECOLI (P31828), PQQL_HAEIN (P45181), PTRA_ECO57 (Q8X6M8), PTRA_ECOL6 (Q8CVS2), PTRA_ECOLI (P05458), PTRA_SALTY (Q8ZMB5), PTRA_SHIFL (Q83QC3), QCR1_EUGGR (P43264), QCR2_BOVIN (P23004), QCR2_HUMAN (P22695), QCR2_MOUSE (Q9DB77), QCR2_RAT(P32551), QCR2_YARLI (Q6C2E3), QCR2_YEAST (P07257), SDP_EIMBO (P42789), STE23_YEAST (Q06010), UCR1_CAEEL (P98080), Y210_RICTY (Q68XF0), Y219_RICPR (O05945), Y2782_MYCTO (P9WHT4), Y2782_MYCTU (P9WHT5), Y2805_MYCBO (P0A5S9), Y293_RICCN (Q92IX7), Y338_RICFE (Q4UML9), Y4WA_SINFN (P55679), Y522_RICBR (Q1RJ61), Y5738_STRCO (O86835), Y855_MYCLE (O32965), YMXG_BACSU (Q04805), YQA4_CAEEL (Q10040)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
40 sequences
ALBF_BACIU (Q8RKH2), ALBF_BACSU (P71006), MPPA_BLAEM (P97997), PREP1_ARATH (Q9LJL3), PREP2_ARATH (Q8VY06), PREP_ASPFU (Q4WP38), PREP_ASPOR (Q2UGN1), PREP_CANAL (Q5A301), PREP_CANGA (Q6FUI7), PREP_DANRE (Q7ZVZ6), PREP_DEBHA (Q6BTC0), PREP_DROME (Q9V9E3), PREP_EMENI (Q5B6H7), PREP_EREGS (Q759T9), PREP_GIBZE (Q4IA56), PREP_HUMAN (Q5JRX3), PREP_KLULA (Q6CWW6), PREP_MOUSE (Q8K411), PREP_NEUCR (Q7S7C0), PREP_PONAB (Q5RDG3), PREP_SCHPO (O42908), PREP_XENLA (Q6PF24), PREP_XENTR (Q28BR5), PREP_YARLI (Q6C0U8), PREP_YEAST (P32898), PTRA_SALTI (Q8Z418), QCR1_BOVIN (P31800), QCR1_HUMAN (P31930), QCR1_MOUSE (Q9CZ13), QCR1_YEAST (P07256), QCR2_EUGGR (P43265), SPP_ARATH (Q9FIH8), SPP_ORYSI (B8B0E2), SPP_ORYSJ (Q69TY5), SPP_PEA (Q40983), Y4WB_SINFN (P55680), YHJJ_ECOLI (P37648), YHJJ_SALTI (Q8Z286), YHJJ_SALTY (P50335), YMFH_BACSU (O31766)» more |
| PDB [Detailed view] |
128 PDB
1BCC; 1BE3; 1BGY; 1EZV; 1HR6; 1HR7; 1HR8; 1HR9; 1KB9; 1KYO; 1L0L; 1L0N; 1NTK; 1NTM; 1NTZ; 1NU1; 1P84; 1PP9; 1PPJ; 1Q2L; 1QCR; 1SQB; 1SQP; 1SQQ; 1SQV; 1SQX; 2A06; 2BCC; 2FYU; 2IBZ; 2JG4; 2YBB; 3BCC; 3CX5; 3CXH; 3P7L; 3QZ2; 3TUV; 4D6T; 4D6U; 4DTT; 4IFH; 4IOF; 4PD4; 4RE9; 5GPN; 5KLV; 5LUF; 5NMI; 5OKD; 5UOE; 5XTE; 5XTH; 5XTI; 6B3Q; 6B70; 6B7Y; 6B7Z; 6BF6; 6BF7; 6BF8; 6BF9; 6BFC; 6FO0; 6FO2; 6FO6; 6GIQ; 6HAW; 6HU9; 6NHG; 6OFS; 6OFT; 6T0B; 6T15; 6XVF; 6YMX; 6ZFS; 6ZFT; 6ZFU; 7DGQ; 7DGR; 7DGS; 7DKF; 7K1D; 7K1E; 7K1F; 7O37; 7O3C; 7O3E; 7O3H; 7R3V; 7RZE; 7RZF; 7RZG; 7RZH; 7RZI; 7TAY; 7TZ6; 8AB6; 8AB7; 8AB8; 8AB9; 8ABA; 8ABB; 8ABE; 8ABF; 8ABG; 8ABH; 8ABI; 8ABJ; 8ABK; 8ABL; 8ABM; 8AC3; 8AC4; 8AC5; 8BEP; 8BPX; 8BQ5; 8BQ6; 8E7S; 8EC0; 8IUF; 8IUJ; 8PW5; 8PW6; 8PW7; 8Q1B » more |