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annotation rule: PRU10096 |
Accession | PRU10096 |
Dates | 16-OCT-2006 (Created) 22-NOV-2019 (Last updated, Version 5) |
Data class | Domain |
Predictors | PROSITE; PS00143; INSULINASE |
Name | Insulinase family, zinc-binding region |
Function | Undefined. |
+ AltName: Full=Pitrilysin; EC 3.4.24.55; |
Catalytic activity | Reaction=Preferential cleavage of 16-Tyr-|-Leu-17 and 25-Phe-|-Tyr-26 bonds of oxidized insulin B chain. Also acts on other substrates of Mw less than 7 kDa such as insulin and glucagon.; EC=3.4.24.55; |
From: PS00143 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
METAL | 4 | 4 | Zinc | |||||||||
ACT_SITE | 7 | 7 | Proton acceptor | |||||||||
METAL | 8 | 8 | Zinc |
Size range | unlimited amino acids |
Related rules | None |
Repeats | 1 |
Topology | Undefined |
Example | P27508 (PQQF_KLEPN) |
Scope | Eukaryota
Bacteria |
Bacteria | [32] | |
Eukaryota | [82] | |
All | [ 114 ] |