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PROSITE entry PS00145


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General information about the entry

Entry name [info] UREASE_2
Accession [info] PS00145
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00133

Name and characterization of the entry

Description [info] Urease active site.
Pattern [info] 
[LIVM](2)-[CT]-H-[HNG]-L-x(3)-[LIVM]-x(2)-D-[LIVM]-x-F-[AS].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 264 in 264 different sequences
Number of true positive hits 264 in 264 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 10
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 96.35 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 264 sequences 

URE11_BRUA2 (Q2YPD5), URE11_BRUAB (Q93T81), URE11_BRUME (Q8YF72), 

URE11_BRUSU (Q8G2P8), URE11_PSEU2 (Q4ZUD2), URE11_STRCO (Q9FCD3), 
URE12_BRUA2 (Q2YQD8), URE12_BRUAB (Q57CE8), URE12_BRUME (Q8YHZ8), 
URE12_BRUSU (Q8FZW2), URE12_PSEU2 (Q4ZN06), URE12_PSYCK (Q1QC36), 
URE12_STRAW (Q826R9), URE1_ACET2  (A3DGF8), URE1_ACIAD  (Q6FD83), 
URE1_ACTP2  (A3N2R4), URE1_ACTP7  (B3H2L3), URE1_ACTPJ  (B0BRU2), 
URE1_ACTPL  (O54420), URE1_AGRFC  (Q8UCT2), URE1_ALBFT  (Q21SZ2), 
URE1_ALCBS  (Q0VKY1), URE1_ALIB4  (A8ESZ8), URE1_ALIF1  (Q5E728), 
URE1_ALIFM  (B5FBC6), URE1_ALLAM  (B9JR81), URE1_ALTMD  (B4RSX9), 
URE1_ANADF  (A7HHN1), URE1_ANASK  (B4UFU2), URE1_ARTS2  (A0JRH4), 
URE1_AZOSB  (A1KBB4), URE1_BACC1  (Q733J6), URE1_BACSB  (Q07397), 
URE1_BACSU  (P77837), URE1_BACVZ  (A7Z9N4), URE1_BEII9  (B2IIJ1), 
URE1_BLOFL  (Q7VRS6), URE1_BLOPB  (Q492E9), URE1_BORBR  (O08400), 
URE1_BORPA  (Q7W417), URE1_BORPE  (Q7VUD3), URE1_BRADU  (Q89UG0), 
URE1_BURA4  (B1YUF9), URE1_BURCH  (A0K576), URE1_BURCJ  (B4ECC7), 
URE1_BURCM  (Q0BHN5), URE1_BURL3  (Q39IW3), URE1_BURM1  (A9AF72), 
URE1_BURM7  (A3MMV2), URE1_BURM9  (A2S996), URE1_BURMA  (Q62HS0), 
URE1_BURMS  (A1V1G6), URE1_BURO0  (B1JX29), URE1_BURO1  (Q1BYH2), 
URE1_BURP0  (A3NYC9), URE1_BURP1  (Q3JPJ6), URE1_BURP6  (A3NCL7), 
URE1_BURPS  (Q63RL3), URE1_BURTA  (Q2SYF7), URE1_BURVG  (A4JC42), 
URE1_CAMLA  (Q5FB23), URE1_CERS1  (A3PL38), URE1_CERS4  (Q3J154), 
URE1_CERS5  (A4WR75), URE1_CERSK  (B9KK46), URE1_CHESB  (Q11EW4), 
URE1_CITK8  (A8APV0), URE1_CLOPF  (P94669), URE1_COREF  (Q8FQX2), 
URE1_CORU7  (B1VHT2), URE1_CUPNH  (Q0KCP6), URE1_CUPPJ  (Q473Q9), 
URE1_CYAP4  (B8HW50), URE1_CYTH3  (Q11VN3), URE1_DECAR  (Q47G55), 
URE1_DEIRA  (Q9RYJ4), URE1_DELAS  (A9BUC4), URE1_DINSH  (A8LRS0), 
URE1_ECO57  (Q8XAG0), URE1_ECO5E  (B5YUX3), URE1_EDWI9  (C5BBR6), 
URE1_ENT38  (A4WEJ5), URE1_FLAJ1  (A5FAD1), URE1_FRAAA  (Q0RQS0), 
URE1_FRACC  (Q2JES6), URE1_GEOKA  (Q5KYM1), URE1_GLOC7  (B7K912), 
URE1_HAEI8  (Q4QN09), URE1_HAEIE  (A5U9V6), URE1_HAEIG  (A5UH45), 
URE1_HAEIN  (P44391), URE1_HAHCH  (Q2SDQ1), URE1_HALH5  (Q9KG59), 
URE1_HALMA  (Q75ZQ5), URE1_HALWD  (Q18EB9), URE1_HELFC  (Q08716), 
URE1_HELHE  (P42823), URE1_HELHP  (Q93PJ4), URE1_HELP2  (B6JPH5), 
URE1_HELPG  (B5Z674), URE1_HELPH  (Q1CV82), URE1_HELPJ  (P69997), 
URE1_HELPS  (B2UW70), URE1_HELPY  (P69996), URE1_HERA2  (A9AZE6), 
URE1_JANMA  (A6SZ07), URE1_JANSC  (Q28RJ3), URE1_KLEAE  (P18314), 
URE1_KLEP3  (B5XU27), URE1_KLEP7  (A6TE42), URE1_KOCRD  (B2GI06), 
URE1_LACP7  (A9KJR9), URE1_LARHH  (C1D5Z8), URE1_LEPCP  (B1Y3V1), 
URE1_LIMFE  (P26929), URE1_MAGMM  (A0L6F2), URE1_MARMS  (A6VTV8), 
URE1_MARN8  (A1U4Z8), URE1_METFK  (Q1H0F2), URE1_METPP  (A2SDJ0), 
URE1_METSB  (B8EPU9), URE1_MICAN  (B0JKA1), URE1_MYCA9  (B1MB85), 
URE1_MYCBO  (P0A661), URE1_MYCBP  (A1KJR2), URE1_MYCBT  (C1APC7), 
URE1_MYCMM  (B2HSZ2), URE1_MYCS2  (A0QYE0), URE1_MYCSJ  (A3Q0D5), 
URE1_MYCSK  (A1UGT5), URE1_MYCSS  (Q1B872), URE1_MYCTA  (A5U3L7), 
URE1_MYCTO  (P9WFF0), URE1_MYCTU  (P9WFF1), URE1_MYCUA  (A0PSG2), 
URE1_MYCVP  (A1T9N4), URE1_NATPD  (Q3IRZ5), URE1_NITMU  (Q2Y9M7), 
URE1_NITOC  (Q3J770), URE1_NOCFA  (Q5YWR8), URE1_NOSP7  (B2IT66), 
URE1_NOSS1  (Q8YQZ0), URE1_OPITP  (B1ZP06), URE1_PAEAT  (A1R1C5), 
URE1_PARC0  (A1TSZ6), URE1_PARDP  (A1B1B9), URE1_PARMW  (Q7U3I3), 
URE1_PARS2  (A8L7B0), URE1_PHOLL  (Q7N4Y7), URE1_POLAQ  (A4SY44), 
URE1_POLNA  (A1VKW3), URE1_POLSJ  (Q12DU3), URE1_PROHU  (P16122), 
URE1_PROM0  (A3PCP1), URE1_PROM1  (A2C4S2), URE1_PROM2  (A8G4K9), 
URE1_PROM3  (A2CE01), URE1_PROM9  (Q31B49), URE1_PROMH  (P17086), 
URE1_PROMM  (Q7V3V2), URE1_PROMP  (Q7V1B6), URE1_PROMS  (A2BQW8), 
URE1_PROMT  (Q46IY3), URE1_PROS9  (Q9L644), URE1_PSE14  (Q48DE6), 
URE1_PSEAE  (Q9HUU5), URE1_PSECP  (B8HA07), URE1_PSEE4  (Q1IBP0), 
URE1_PSEF5  (Q4KJ10), URE1_PSEP1  (A5W4B6), URE1_PSEPF  (Q3KIT2), 
URE1_PSEPG  (B0KUZ7), URE1_PSEPK  (Q88J04), URE1_PSEPW  (B1J815), 
URE1_PSESM  (Q87VP0), URE1_PSYIN  (A1SYY1), URE1_RALN1  (Q8XXT1), 
URE1_RHIE6  (B3PXB3), URE1_RHIEC  (Q2K517), URE1_RHIJ3  (Q1MCV9), 
URE1_RHILO  (Q98CY9), URE1_RHILW  (B5ZMP0), URE1_RHIME  (P42885), 
URE1_RHIR8  (B9J8M3), URE1_RHOJR  (Q0S4S7), URE1_RHOOB  (C1AXZ2), 
URE1_RHOP2  (Q2IZ49), URE1_RHOP5  (Q07K73), URE1_RHOPA  (Q6N3N3), 
URE1_RHOPB  (Q210F9), URE1_RHOPS  (Q133L6), URE1_RHOPT  (B3QGK1), 
URE1_ROSDO  (Q161S8), URE1_RUEPO  (Q5LSQ2), URE1_RUEST  (Q1GJP8), 
URE1_SACD2  (Q21P94), URE1_SHEHH  (B0TT71), URE1_SINFN  (C3MGI5), 
URE1_SINMW  (A6UC35), URE1_SORC5  (A9GP84), URE1_SPOPA  (P41020), 
URE1_STAA1  (A7X5M3), URE1_STAA2  (A6U414), URE1_STAA3  (Q2FEK3), 
URE1_STAA8  (Q2G2K5), URE1_STAA9  (A5IV71), URE1_STAAB  (Q2YYQ6), 
URE1_STAAC  (Q5HDR8), URE1_STAAE  (A6QJD0), URE1_STAAM  (P67403), 
URE1_STAAN  (P67404), URE1_STAAR  (Q6GEE4), URE1_STAAS  (Q6G732), 
URE1_STAAT  (A8Z387), URE1_STAAW  (P67405), URE1_STACT  (B9DLY0), 
URE1_STAEQ  (Q5HLW1), URE1_STAES  (Q8CNC9), URE1_STAS1  (Q4A0J5), 
URE1_STAXY  (P42873), URE1_STRE5  (P50047), URE1_STRT1  (Q5M1G6), 
URE1_STRT2  (Q5M607), URE1_STRTD  (Q03ME3), URE1_SYNJA  (Q2JWP0), 
URE1_SYNJB  (Q2JQ88), URE1_SYNPV  (O87402), URE1_SYNR3  (A5GWV7), 
URE1_SYNS3  (Q0I656), URE1_SYNS9  (Q3AVR1), URE1_SYNSC  (Q3AGD0), 
URE1_SYNY3  (P73061), URE1_TERTT  (C5BUN9), URE1_THEVB  (Q8DMV6), 
URE1_TOLAT  (C4LF63), URE1_TRIEI  (Q117Z3), URE1_TRIV2  (Q3M712), 
URE1_UREP2  (B1AJ73), URE1_UREPA  (P0C7K7), URE1_UREU1  (B5ZBS9), 
URE1_UREUR  (P0CB00), URE1_VARPS  (C5CY00), URE1_VEREI  (A1WIM3), 
URE1_YERE8  (A1JKD9), URE1_YEREN  (P31494), URE1_YERP3  (A7FFN2), 
URE1_YERPA  (Q1C5B3), URE1_YERPB  (B2KAA4), URE1_YERPE  (Q9ZFR9), 
URE1_YERPG  (A9R3V0), URE1_YERPN  (Q1CKJ9), URE1_YERPP  (A4TL32), 
URE1_YERPS  (P52313), URE1_YERPY  (B1JR71), UREA_ARATH  (Q9SR52), 
UREA_ASPFU  (Q6A3P9), UREA_CANEN  (P07374), UREA_CRYNB  (P0CS23), 
UREA_CRYNH  (O13465), UREA_CRYNJ  (P0CS22), UREA_ORYSI  (E0ZS48), 
UREA_ORYSJ  (B9GCH9), UREA_SCHPO  (O00084), UREA_SOYBN  (P08298)
» more

UniProtKB/Swiss-Prot
False negative sequences		 10 sequences 

URE11_PSYCK (Q1QCE0), URE11_STRAW (Q82JN9), URE12_STRCO (O86508), 

URE1_AZOPC  (B6YQL8), URE1_CALS8  (A4XMA9), URE1_CORGL  (Q79VJ3), 
URE1_MICLC  (C5C8U3), URE1_PSET1  (Q3IH68), URE1_SULTO  (Q972W0), 
UREA2_CANEN (E6Y5X0)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 4 sequences 

URE1_ECOLX  (Q03284), URE1_HELMU  (P50045), URE1_MORMO  (P17337), 

URE1_PHODD  (P50046)
» more

PDB
[Detailed view]		 62 PDB

1A5K; 1A5L; 1A5M; 1A5N; 1A5O; 1E9Z; 1EF2; 1EJR; 1EJS; 1EJT; 1EJW; 1EJX; 1FWI; 1FWJ; 1IE7; 1KRA; 1KRB; 1S3T; 1UBP; 2KAU; 2UBP; 3LA4; 3UBP; 4AC7; 4CEU; 4CEX; 4EP8; 4EPB; 4EPD; 4EPE; 4GOA; 4GY7; 4H9M; 4UBP; 5A6T; 5FSD; 5FSE; 5OL4; 6G48; 6H8J; 6I9Y; 6QDY; 6QSU; 6RKG; 6RP1; 6ZJA; 6ZNY; 6ZNZ; 6ZO0; 6ZO1; 6ZO2; 6ZO3; 7B58; 7B59; 7B5A; 7KNS; 7P7N; 7P7O; 7ZCY; 8A18; 8HC1; 8Q2E
» more