PROSITE logo

PROSITE entry PS00145


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] UREASE_2
Accession [info] PS00145
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00133

Name and characterization of the entry

Description [info] Urease active site.
Pattern [info] 
[LIVM](2)-[CT]-H-[HNG]-L-x(3)-[LIVM]-x(2)-D-[LIVM]-x-F-[AS].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 264 in 264 different sequences
Number of true positive hits 264 in 264 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 10
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 96.35 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 264 sequences 

URE11_BRUA2 (Q2YPD5), URE11_BRUAB (Q93T81), URE11_BRUME (Q8YF72), 

URE11_BRUSU (Q8G2P8), URE11_PSEU2 (Q4ZUD2), URE11_STRCO (Q9FCD3), 
URE12_BRUA2 (Q2YQD8), URE12_BRUAB (Q57CE8), URE12_BRUME (Q8YHZ8), 
URE12_BRUSU (Q8FZW2), URE12_PSEU2 (Q4ZN06), URE12_PSYCK (Q1QC36), 
URE12_STRAW (Q826R9), URE1_ACET2  (A3DGF8), URE1_ACIAD  (Q6FD83), 
URE1_ACTP2  (A3N2R4), URE1_ACTP7  (B3H2L3), URE1_ACTPJ  (B0BRU2), 
URE1_ACTPL  (O54420), URE1_AGRFC  (Q8UCT2), URE1_ALBFT  (Q21SZ2), 
URE1_ALCBS  (Q0VKY1), URE1_ALIB4  (A8ESZ8), URE1_ALIF1  (Q5E728), 
URE1_ALIFM  (B5FBC6), URE1_ALLAM  (B9JR81), URE1_ALTMD  (B4RSX9), 
URE1_ANADF  (A7HHN1), URE1_ANASK  (B4UFU2), URE1_ARTS2  (A0JRH4), 
URE1_AZOSB  (A1KBB4), URE1_BACC1  (Q733J6), URE1_BACSB  (Q07397), 
URE1_BACSU  (P77837), URE1_BACVZ  (A7Z9N4), URE1_BEII9  (B2IIJ1), 
URE1_BLOFL  (Q7VRS6), URE1_BLOPB  (Q492E9), URE1_BORBR  (O08400), 
URE1_BORPA  (Q7W417), URE1_BORPE  (Q7VUD3), URE1_BRADU  (Q89UG0), 
URE1_BURA4  (B1YUF9), URE1_BURCH  (A0K576), URE1_BURCJ  (B4ECC7), 
URE1_BURCM  (Q0BHN5), URE1_BURL3  (Q39IW3), URE1_BURM1  (A9AF72), 
URE1_BURM7  (A3MMV2), URE1_BURM9  (A2S996), URE1_BURMA  (Q62HS0), 
URE1_BURMS  (A1V1G6), URE1_BURO0  (B1JX29), URE1_BURO1  (Q1BYH2), 
URE1_BURP0  (A3NYC9), URE1_BURP1  (Q3JPJ6), URE1_BURP6  (A3NCL7), 
URE1_BURPS  (Q63RL3), URE1_BURTA  (Q2SYF7), URE1_BURVG  (A4JC42), 
URE1_CAMLA  (Q5FB23), URE1_CERS1  (A3PL38), URE1_CERS4  (Q3J154), 
URE1_CERS5  (A4WR75), URE1_CERSK  (B9KK46), URE1_CHESB  (Q11EW4), 
URE1_CITK8  (A8APV0), URE1_CLOPF  (P94669), URE1_COREF  (Q8FQX2), 
URE1_CORU7  (B1VHT2), URE1_CUPNH  (Q0KCP6), URE1_CUPPJ  (Q473Q9), 
URE1_CYAP4  (B8HW50), URE1_CYTH3  (Q11VN3), URE1_DECAR  (Q47G55), 
URE1_DEIRA  (Q9RYJ4), URE1_DELAS  (A9BUC4), URE1_DINSH  (A8LRS0), 
URE1_ECO57  (Q8XAG0), URE1_ECO5E  (B5YUX3), URE1_EDWI9  (C5BBR6), 
URE1_ENT38  (A4WEJ5), URE1_FLAJ1  (A5FAD1), URE1_FRAAA  (Q0RQS0), 
URE1_FRACC  (Q2JES6), URE1_GEOKA  (Q5KYM1), URE1_GLOC7  (B7K912), 
URE1_HAEI8  (Q4QN09), URE1_HAEIE  (A5U9V6), URE1_HAEIG  (A5UH45), 
URE1_HAEIN  (P44391), URE1_HAHCH  (Q2SDQ1), URE1_HALH5  (Q9KG59), 
URE1_HALMA  (Q75ZQ5), URE1_HALWD  (Q18EB9), URE1_HELFC  (Q08716), 
URE1_HELHE  (P42823), URE1_HELHP  (Q93PJ4), URE1_HELP2  (B6JPH5), 
URE1_HELPG  (B5Z674), URE1_HELPH  (Q1CV82), URE1_HELPJ  (P69997), 
URE1_HELPS  (B2UW70), URE1_HELPY  (P69996), URE1_HERA2  (A9AZE6), 
URE1_JANMA  (A6SZ07), URE1_JANSC  (Q28RJ3), URE1_KLEAE  (P18314), 
URE1_KLEP3  (B5XU27), URE1_KLEP7  (A6TE42), URE1_KOCRD  (B2GI06), 
URE1_LACP7  (A9KJR9), URE1_LARHH  (C1D5Z8), URE1_LEPCP  (B1Y3V1), 
URE1_LIMFE  (P26929), URE1_MAGMM  (A0L6F2), URE1_MARMS  (A6VTV8), 
URE1_MARN8  (A1U4Z8), URE1_METFK  (Q1H0F2), URE1_METPP  (A2SDJ0), 
URE1_METSB  (B8EPU9), URE1_MICAN  (B0JKA1), URE1_MYCA9  (B1MB85), 
URE1_MYCBO  (P0A661), URE1_MYCBP  (A1KJR2), URE1_MYCBT  (C1APC7), 
URE1_MYCMM  (B2HSZ2), URE1_MYCS2  (A0QYE0), URE1_MYCSJ  (A3Q0D5), 
URE1_MYCSK  (A1UGT5), URE1_MYCSS  (Q1B872), URE1_MYCTA  (A5U3L7), 
URE1_MYCTO  (P9WFF0), URE1_MYCTU  (P9WFF1), URE1_MYCUA  (A0PSG2), 
URE1_MYCVP  (A1T9N4), URE1_NATPD  (Q3IRZ5), URE1_NITMU  (Q2Y9M7), 
URE1_NITOC  (Q3J770), URE1_NOCFA  (Q5YWR8), URE1_NOSP7  (B2IT66), 
URE1_NOSS1  (Q8YQZ0), URE1_OPITP  (B1ZP06), URE1_PAEAT  (A1R1C5), 
URE1_PARC0  (A1TSZ6), URE1_PARDP  (A1B1B9), URE1_PARMW  (Q7U3I3), 
URE1_PARS2  (A8L7B0), URE1_PHOLL  (Q7N4Y7), URE1_POLAQ  (A4SY44), 
URE1_POLNA  (A1VKW3), URE1_POLSJ  (Q12DU3), URE1_PROHU  (P16122), 
URE1_PROM0  (A3PCP1), URE1_PROM1  (A2C4S2), URE1_PROM2  (A8G4K9), 
URE1_PROM3  (A2CE01), URE1_PROM9  (Q31B49), URE1_PROMH  (P17086), 
URE1_PROMM  (Q7V3V2), URE1_PROMP  (Q7V1B6), URE1_PROMS  (A2BQW8), 
URE1_PROMT  (Q46IY3), URE1_PROS9  (Q9L644), URE1_PSE14  (Q48DE6), 
URE1_PSEAE  (Q9HUU5), URE1_PSECP  (B8HA07), URE1_PSEE4  (Q1IBP0), 
URE1_PSEF5  (Q4KJ10), URE1_PSEP1  (A5W4B6), URE1_PSEPF  (Q3KIT2), 
URE1_PSEPG  (B0KUZ7), URE1_PSEPK  (Q88J04), URE1_PSEPW  (B1J815), 
URE1_PSESM  (Q87VP0), URE1_PSYIN  (A1SYY1), URE1_RALN1  (Q8XXT1), 
URE1_RHIE6  (B3PXB3), URE1_RHIEC  (Q2K517), URE1_RHIJ3  (Q1MCV9), 
URE1_RHILO  (Q98CY9), URE1_RHILW  (B5ZMP0), URE1_RHIME  (P42885), 
URE1_RHIR8  (B9J8M3), URE1_RHOJR  (Q0S4S7), URE1_RHOOB  (C1AXZ2), 
URE1_RHOP2  (Q2IZ49), URE1_RHOP5  (Q07K73), URE1_RHOPA  (Q6N3N3), 
URE1_RHOPB  (Q210F9), URE1_RHOPS  (Q133L6), URE1_RHOPT  (B3QGK1), 
URE1_ROSDO  (Q161S8), URE1_RUEPO  (Q5LSQ2), URE1_RUEST  (Q1GJP8), 
URE1_SACD2  (Q21P94), URE1_SHEHH  (B0TT71), URE1_SINFN  (C3MGI5), 
URE1_SINMW  (A6UC35), URE1_SORC5  (A9GP84), URE1_SPOPA  (P41020), 
URE1_STAA1  (A7X5M3), URE1_STAA2  (A6U414), URE1_STAA3  (Q2FEK3), 
URE1_STAA8  (Q2G2K5), URE1_STAA9  (A5IV71), URE1_STAAB  (Q2YYQ6), 
URE1_STAAC  (Q5HDR8), URE1_STAAE  (A6QJD0), URE1_STAAM  (P67403), 
URE1_STAAN  (P67404), URE1_STAAR  (Q6GEE4), URE1_STAAS  (Q6G732), 
URE1_STAAT  (A8Z387), URE1_STAAW  (P67405), URE1_STACT  (B9DLY0), 
URE1_STAEQ  (Q5HLW1), URE1_STAES  (Q8CNC9), URE1_STAS1  (Q4A0J5), 
URE1_STAXY  (P42873), URE1_STRE5  (P50047), URE1_STRT1  (Q5M1G6), 
URE1_STRT2  (Q5M607), URE1_STRTD  (Q03ME3), URE1_SYNJA  (Q2JWP0), 
URE1_SYNJB  (Q2JQ88), URE1_SYNPV  (O87402), URE1_SYNR3  (A5GWV7), 
URE1_SYNS3  (Q0I656), URE1_SYNS9  (Q3AVR1), URE1_SYNSC  (Q3AGD0), 
URE1_SYNY3  (P73061), URE1_TERTT  (C5BUN9), URE1_THEVB  (Q8DMV6), 
URE1_TOLAT  (C4LF63), URE1_TRIEI  (Q117Z3), URE1_TRIV2  (Q3M712), 
URE1_UREP2  (B1AJ73), URE1_UREPA  (P0C7K7), URE1_UREU1  (B5ZBS9), 
URE1_UREUR  (P0CB00), URE1_VARPS  (C5CY00), URE1_VEREI  (A1WIM3), 
URE1_YERE8  (A1JKD9), URE1_YEREN  (P31494), URE1_YERP3  (A7FFN2), 
URE1_YERPA  (Q1C5B3), URE1_YERPB  (B2KAA4), URE1_YERPE  (Q9ZFR9), 
URE1_YERPG  (A9R3V0), URE1_YERPN  (Q1CKJ9), URE1_YERPP  (A4TL32), 
URE1_YERPS  (P52313), URE1_YERPY  (B1JR71), UREA_ARATH  (Q9SR52), 
UREA_ASPFU  (Q6A3P9), UREA_CANEN  (P07374), UREA_CRYNB  (P0CS23), 
UREA_CRYNH  (O13465), UREA_CRYNJ  (P0CS22), UREA_ORYSI  (E0ZS48), 
UREA_ORYSJ  (B9GCH9), UREA_SCHPO  (O00084), UREA_SOYBN  (P08298)
» more

UniProtKB/Swiss-Prot
False negative sequences		 10 sequences 

URE11_PSYCK (Q1QCE0), URE11_STRAW (Q82JN9), URE12_STRCO (O86508), 

URE1_AZOPC  (B6YQL8), URE1_CALS8  (A4XMA9), URE1_CORGL  (Q79VJ3), 
URE1_MICLC  (C5C8U3), URE1_PSET1  (Q3IH68), URE1_SULTO  (Q972W0), 
UREA2_CANEN (E6Y5X0)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 4 sequences 

URE1_ECOLX  (Q03284), URE1_HELMU  (P50045), URE1_MORMO  (P17337), 

URE1_PHODD  (P50046)
» more

PDB
[Detailed view]		 62 PDB

1A5K; 1A5L; 1A5M; 1A5N; 1A5O; 1E9Z; 1EF2; 1EJR; 1EJS; 1EJT; 1EJW; 1EJX; 1FWI; 1FWJ; 1IE7; 1KRA; 1KRB; 1S3T; 1UBP; 2KAU; 2UBP; 3LA4; 3UBP; 4AC7; 4CEU; 4CEX; 4EP8; 4EPB; 4EPD; 4EPE; 4GOA; 4GY7; 4H9M; 4UBP; 5A6T; 5FSD; 5FSE; 5OL4; 6G48; 6H8J; 6I9Y; 6QDY; 6QSU; 6RKG; 6RP1; 6ZJA; 6ZNY; 6ZNZ; 6ZO0; 6ZO1; 6ZO2; 6ZO3; 7B58; 7B59; 7B5A; 7KNS; 7P7N; 7P7O; 7ZCY; 8A18; 8HC1; 8Q2E
» more