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Entry: PS00187

General information about the entry

Entry name [info] TPP_ENZYMES
Accession [info] PS00187
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1995 DATA UPDATE;
23-FEB-2022 INFO UPDATE.
PROSITE Doc. [info] PDOC00166

Name and characterization of the entry

Description [info] Thiamine pyrophosphate enzymes signature.
Pattern [info] 
[LIVMF]-[GSA]-x(5)-P-x(4)-[LIVMFYW]-x-[LIVMF]-x-G-D-[GSA]-[GSAC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2022_01 which contains 566'996 sequence entries.


Total number of hits 114 in 114 different sequences
Number of true positive hits 108 in 108 different sequences
Number of 'unknown' hits 0
Number of false positive hits 6 in 6 different sequences
Number of false negative sequences 82
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 94.74 %
Recall (true positives / (true positives + false negatives)) 56.84 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 108 sequences 

ARUI_PSEAE  (Q9HUI8    ), CEAS_STRCL  (Q9LCV9    ), DCIP_ENTCL  (P23234    ), 

HACL1_DICDI (Q54DA9    ), HACL2_BOVIN (A6QQT9    ), HACL2_CAEEL (O61856    ), 
HACL2_DANRE (Q6NV04    ), HACL2_HUMAN (A1L0T0    ), HACL2_MOUSE (Q8BU33    ), 
HACL2_XENLA (Q6DDK5    ), HACL_ARATH  (Q9LF46    ), HACL_ORYSJ  (Q0JMH0    ), 
HICL_ACTC0  (P0DUV9    ), ILVB1_BRANA (P27818    ), ILVB1_MYCTO (P9WG40    ), 
ILVB1_MYCTU (P9WG41    ), ILVB1_TOBAC (P09342    ), ILVB2_BRANA (P14874    ), 
ILVB2_MYCTU (O06335    ), ILVB2_TOBAC (P09114    ), ILVB3_BRANA (P27819    ), 
ILVB_ARATH  (P17597    ), ILVB_CORGL  (P42463    ), ILVB_CRYNH  (Q6SSJ3    ), 
ILVB_CRYNJ  (Q5KPJ5    ), ILVB_CYACA  (O19929    ), ILVB_ECOLI  (P08142    ), 
ILVB_GUITH  (O78518    ), ILVB_KLEPN  (P27696    ), ILVB_LACLA  (Q02137    ), 
ILVB_METAO  (O08353    ), ILVB_METJA  (Q57725    ), ILVB_MYCAV  (Q59498    ), 
ILVB_MYCBO  (P0A623    ), ILVB_MYCLE  (O33112    ), ILVB_NEOYE  (Q1XDF6    ), 
ILVB_PARMW  (Q7U5G1    ), ILVB_PORPU  (P69683    ), ILVB_PORUM  (P69684    ), 
ILVB_RAOTE  (Q04524    ), ILVB_SCHPO  (P36620    ), ILVB_YEAST  (P07342    ), 
ILVG_ECOLI  (P0DP90    ), ILVG_MYCBO  (P66947    ), ILVG_MYCTO  (P9WG38    ), 
ILVG_MYCTU  (P9WG39    ), ILVI_BUCAI  (P57321    ), ILVI_BUCAP  (O85293    ), 
ILVI_BUCBP  (Q89AP7    ), ILVI_BUCSC  (Q9RQ65    ), ILVI_ECOLI  (P00893    ), 
ILVI_HAEIN  (P45261    ), ILVI_SALTY  (P40811    ), ILVX_BACSU  (Q04789    ), 
IOLD1_BACCZ (Q63B73    ), IOLD2_BACCZ (Q4V1F5    ), IOLD_ALKHC  (Q9KAG9    ), 
IOLD_BACAA  (C3PAZ3    ), IOLD_BACAC  (C3LHY1    ), IOLD_BACAH  (A0REB6    ), 
IOLD_BACAN  (Q81QB5    ), IOLD_BACC0  (B7JPM3    ), IOLD_BACC3  (C1EVJ3    ), 
IOLD_BACHK  (Q6HIK2    ), IOLD_BACLD  (Q65D03    ), IOLD_BACSK  (Q5WKY8    ), 
IOLD_BACSU  (P42415    ), IOLD_BACVZ  (A7ZAH8    ), IOLD_CLOBA  (B2V4K0    ), 
IOLD_CLOBB  (B2TJ86    ), IOLD_CLOP1  (Q0TUZ2    ), IOLD_CLOPE  (Q8XP76    ), 
IOLD_GEOKA  (Q5KYR0    ), IOLD_GEOTN  (A4IPB6    ), IOLD_LACCA  (A5YBJ6    ), 
KDC_MYCA1   (A0QBE6    ), KDC_MYCBO   (Q7U140    ), KDC_MYCBP   (A1KGY5    ), 
KDC_MYCPA   (Q742Q2    ), KDC_MYCTA   (A5U0P1    ), KDC_MYCTO   (P9WG36    ), 
KDC_MYCTU   (P9WG37    ), KDC_MYCUA   (A0PL16    ), MDLC_PSEAE  (Q9HUR2    ), 
MDLC_PSEPU  (P20906    ), PDC1_ARATH  (O82647    ), PDC1_CANAL  (P83779    ), 
PDC1_CANGA  (Q6FJA3    ), PDC1_KLULA  (Q12629    ), PDC1_KLUMA  (P33149    ), 
PDC1_YEAST  (P06169    ), PDC2_SCHPO  (Q92345    ), PDC3_ARATH  (Q9M039    ), 
PDC3_SCHPO  (Q9P7P6    ), PDC4_ARATH  (Q9M040    ), PDC5_YEAST  (P16467    ), 
PDC6_YEAST  (P26263    ), PDC_NEUCR   (P33287    ), PDC_ZYMMO   (P06672    ), 
POXB_ECOLI  (P07003    ), POXB_LACPL  (P37063    ), POXB_STRPN  (Q54970    ), 
PXP1_YEAST  (P39994    ), XSC_DESTI   (Q93PS3    ), XSC_RHIME   (Q92UW6    ), 
XSC_RHOCB   (D5AKX8    ), XSC_ROSNI   (A3SR25    ), YDAP_BACSU  (P96591    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 82 sequences 

COMDE_METAC (Q8TKU6    ), COME_METJA  (P58416    ), COME_METTH  (O27275    ), 

DCIP_AZOBR  (P51852    ), HACL1_HUMAN (Q9UJ83    ), HACL1_MOUSE (Q9QXE0    ), 
HACL1_RAT   (Q8CHM7    ), ILVB_BACSU  (P37251    ), IOLD_CLOTE  (Q898E8    ), 
IOLD_LISIN  (Q92EQ4    ), IOLD_LISMF  (Q723S8    ), IOLD_LISMO  (Q8Y9Y1    ), 
KDC_MYCLE   (Q9CBD6    ), KDC_MYCS2   (A0R480    ), OXC_ECO57   (P0AFI1    ), 
OXC_ECOLI   (P0AFI0    ), OXC_OXAFO   (P40149    ), PDC1_MAIZE  (P28516    ), 
PDC1_ORYSI  (A2Y5L9    ), PDC1_ORYSJ  (Q0DHF6    ), PDC1_PEA    (P51850    ), 
PDC1_SCHPO  (Q09737    ), PDC2_ARATH  (Q9FFT4    ), PDC2_ORYSI  (A2XFI3    ), 
PDC2_ORYSJ  (Q10MW3    ), PDC2_TOBAC  (P51846    ), PDC3_ORYSI  (A2YQ76    ), 
PDC3_ORYSJ  (Q0D3D2    ), PDC4_SCHPO  (O42873    ), PDC_ASPFU   (Q4WXX9    ), 
PDC_ASPOR   (Q2UKV4    ), PDC_ASPPA   (P51844    ), PDC_ASPTN   (Q0CNV1    ), 
PDC_EMENI   (P87208    ), PDC_HANUV   (P34734    ), PHK1_LACPL  (Q88U67    ), 
PHK1_NOSS1  (Q8YWW1    ), PHK1_RHIME  (Q92T74    ), PHK2_LACPL  (Q88S87    ), 
PHK2_NOSS1  (Q8YTZ6    ), PHK2_RHIME  (Q92ZA4    ), PHK_BEII9   (B2IGR2    ), 
PHK_BIFA0   (B8DUT6    ), PHK_BRADU   (Q89S87    ), PHK_BRUA2   (Q2YK44    ), 
PHK_BRUME   (Q8YBL8    ), PHK_BRUSU   (Q8FWR0    ), PHK_CHLTE   (Q8KCA0    ), 
PHK_CLOAB   (Q97JE3    ), PHK_GLOVI   (Q7NLX2    ), PHK_LACLA   (Q9CFH4    ), 
PHK_LATSS   (Q38YY6    ), PHK_METCA   (Q608B0    ), PHK_MYCA1   (A0QGK3    ), 
PHK_MYCPA   (Q73ZM8    ), PHK_NITEU   (Q82T07    ), PHK_NITMU   (Q2YAC5    ), 
PHK_NOCFA   (Q5Z066    ), PHK_PARUW   (Q6MFC0    ), PHK_PEDPA   (Q03H73    ), 
PHK_PSEP1   (A5W384    ), PHK_RHILO   (Q988V7    ), PHK_RHOBA   (Q7UH14    ), 
PHK_RHOP2   (Q2ITA9    ), PHK_RHOPA   (Q6N976    ), PHK_RHOPB   (Q20ZU5    ), 
PHK_RHOPS   (Q13B10    ), PHK_RHOPT   (B3Q8J5    ), PHK_SCHPO   (O74770    ), 
PHK_STRAW   (Q82NM9    ), PHK_STRCO   (Q8CK51    ), PHK_SYNE7   (Q31LF9    ), 
PHK_SYNP6   (Q5N0G7    ), PHK_SYNY3   (P74690    ), PHK_THEVB   (Q8DJN6    ), 
PIGD_SERMA  (Q5W251    ), PIGD_SERS3  (Q5W268    ), PPD_STRHY   (Q54271    ), 
XFP_BIFAS   (Q9AEM9    ), XPKA_LACPE  (Q937F6    ), XSC_ALCXX   (Q84H41    ), 
XSC_CASDE   (Q84H44    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 5 sequences 

ILVB_ARTPT  (P27868    ), PDC1_TOBAC  (P51845    ), PDC2_MAIZE  (Q05326    ), 

PDC2_PEA    (P51851    ), PDC3_MAIZE  (Q05327    )
» more

UniProtKB/Swiss-Prot
False positive sequences		 6 sequences 

COLB_DICDI  (Q8T2A1    ), DXS1_CERS4  (Q3J1A8    ), DXS1_ROSDO  (Q16DV7    ), 

DXS_FUSNN   (Q8R639    ), DXS_RHOCA   (P26242    ), NPHN_MOUSE  (Q9QZS7    )
» more

PDB
[Detailed view]		 114 PDB

1BFD; 1JSC; 1MCZ; 1N0H; 1OVM; 1OZF; 1OZG; 1OZH; 1PI3; 1PO7; 1POW; 1POX; 1PVD; 1PYD; 1Q6Z; 1QPB; 1T9A; 1T9B; 1T9C; 1T9D; 1UPA; 1UPB; 1UPC; 1Y9D; 1YBH; 1YHY; 1YHZ; 1YI0; 1YI1; 1YNO; 1Z8N; 1ZPD; 2EZ4; 2EZ8; 2EZ9; 2EZT; 2EZU; 2FN3; 2FWN; 2IHT; 2IHU; 2IHV; 2V3W; 2VJY; 2VK1; 2VK4; 2VK8; 2W93; 2WVA; 2WVG; 2WVH; 3E9Y; 3EA4; 3EY9; 3EYA; 3F6B; 3F6E; 3FSJ; 3FZN; 3OE1; 4GG1; 4GM0; 4GM1; 4GM4; 4GP9; 4GPE; 4JD5; 4JU8; 4JU9; 4JUA; 4JUB; 4JUC; 4JUD; 4JUF; 4K9K; 4K9L; 4K9M; 4K9N; 4K9O; 4K9P; 4MPJ; 4MPP; 4MPR; 4MQ5; 4MZX; 4QEL; 4ZP1; 5D6R; 5DEI; 5DGD; 5DGT; 5DX6; 5FEM; 5IMS; 5K2O; 5K3S; 5K6Q; 5K6R; 5K6T; 5TMA; 5WDG; 5WJ1; 5WKC; 6BD3; 6BD9; 6EFG; 6EFH; 6HAF; 6LPI; 6M2Y; 6M2Z; 6U9D; 6U9H; 6VZ8
» more

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