PROSITE entry PS00187
View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS00187 |
| Entry name [info] | TPP_ENZYMES |
| Accession [info] | PS00187 |
| Entry type [info] | PATTERN |
| Date [info] |
01-APR-1990 CREATED;
01-NOV-1995 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00166 |
Name and characterization of the entry
| Description [info] | Thiamine pyrophosphate enzymes signature. |
| Pattern [info] |
[LIVMF]-[GSA]-x(5)-P-x(4)-[LIVMFYW]-x-[LIVMF]-x-G-D-[GSA]-[GSAC]. |
Numerical results [info]
| Total number of hits | 116 in 116 different sequences |
| Number of true positive hits | 109 in 109 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 7 in 7 different sequences |
| Number of false negative sequences | 83 |
| Number of 'partial' sequences | 5 |
| Precision (true positives / (true positives + false positives)) | 93.97 % |
| Recall (true positives / (true positives + false negatives)) | 56.77 % |
Comments [info]
| Taxonomic range [info] | Archaea, Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
109 sequences
ARUI_PSEAE (Q9HUI8), CEAS_STRCL (Q9LCV9), CFOL_ASPCN (A0A2I2F2I5), DCIP_ENTCL (P23234), HACL1_DICDI (Q54DA9), HACL2_BOVIN (A6QQT9), HACL2_CAEEL (O61856), HACL2_DANRE (Q6NV04), HACL2_HUMAN (A1L0T0), HACL2_MOUSE (Q8BU33), HACL2_XENLA (Q6DDK5), HACL_ACTC0 (P0DUV9), HACL_ARATH (Q9LF46), HACL_ORYSJ (Q0JMH0), ILVB1_BRANA (P27818), ILVB1_MYCTO (P9WG40), ILVB1_MYCTU (P9WG41), ILVB1_TOBAC (P09342), ILVB2_BRANA (P14874), ILVB2_MYCTU (O06335), ILVB2_TOBAC (P09114), ILVB3_BRANA (P27819), ILVB_ARATH (P17597), ILVB_CORGL (P42463), ILVB_CRYNH (Q6SSJ3), ILVB_CRYNJ (Q5KPJ5), ILVB_CYACA (O19929), ILVB_ECOLI (P08142), ILVB_GUITH (O78518), ILVB_KLEPN (P27696), ILVB_LACLA (Q02137), ILVB_METAO (O08353), ILVB_METJA (Q57725), ILVB_MYCAV (Q59498), ILVB_MYCBO (P0A623), ILVB_MYCLE (O33112), ILVB_PARMW (Q7U5G1), ILVB_PORPU (P69683), ILVB_PORUM (P69684), ILVB_PYRYE (Q1XDF6), ILVB_RAOTE (Q04524), ILVB_SCHPO (P36620), ILVB_YEAST (P07342), ILVG_ECOLI (P0DP90), ILVG_MYCBO (P66947), ILVG_MYCTO (P9WG38), ILVG_MYCTU (P9WG39), ILVI_BUCAI (P57321), ILVI_BUCAP (O85293), ILVI_BUCBP (Q89AP7), ILVI_BUCSC (Q9RQ65), ILVI_ECOLI (P00893), ILVI_HAEIN (P45261), ILVI_SALTY (P40811), ILVX_BACSU (Q04789), IOLD1_BACCZ (Q63B73), IOLD2_BACCZ (Q4V1F5), IOLD_BACAA (C3PAZ3), IOLD_BACAC (C3LHY1), IOLD_BACAH (A0REB6), IOLD_BACAN (Q81QB5), IOLD_BACC0 (B7JPM3), IOLD_BACC3 (C1EVJ3), IOLD_BACHK (Q6HIK2), IOLD_BACLD (Q65D03), IOLD_BACSU (P42415), IOLD_BACVZ (A7ZAH8), IOLD_CLOBA (B2V4K0), IOLD_CLOBB (B2TJ86), IOLD_CLOP1 (Q0TUZ2), IOLD_CLOPE (Q8XP76), IOLD_GEOKA (Q5KYR0), IOLD_GEOTN (A4IPB6), IOLD_HALH5 (Q9KAG9), IOLD_LACCA (A5YBJ6), IOLD_SHOC1 (Q5WKY8), KDC_MYCA1 (A0QBE6), KDC_MYCBO (Q7U140), KDC_MYCBP (A1KGY5), KDC_MYCPA (Q742Q2), KDC_MYCTA (A5U0P1), KDC_MYCTO (P9WG36), KDC_MYCTU (P9WG37), KDC_MYCUA (A0PL16), MDLC_PSEAE (Q9HUR2), MDLC_PSEPU (P20906), PDC1_ARATH (O82647), PDC1_CANAL (P83779), PDC1_CANGA (Q6FJA3), PDC1_KLULA (Q12629), PDC1_KLUMA (P33149), PDC1_YEAST (P06169), PDC2_SCHPO (Q92345), PDC3_ARATH (Q9M039), PDC3_SCHPO (Q9P7P6), PDC4_ARATH (Q9M040), PDC5_YEAST (P16467), PDC6_YEAST (P26263), PDC_NEUCR (P33287), PDC_ZYMMO (P06672), POXB_ECOLI (P07003), POXB_LACPL (P37063), POXB_STRPN (Q54970), PXP1_YEAST (P39994), XSC_DESTI (Q93PS3), XSC_RHIME (Q92UW6), XSC_RHOCB (D5AKX8), XSC_ROSNI (A3SR25), YDAP_BACSU (P96591)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
83 sequences
COMDE_METAC (Q8TKU6), COME_METJA (P58416), COME_METTH (O27275), DCIP_AZOBR (P51852), HACL1_HUMAN (Q9UJ83), HACL1_MOUSE (Q9QXE0), HACL1_RAT (Q8CHM7), ILVB_BACSU (P37251), IOLD_CLOTE (Q898E8), IOLD_LISIN (Q92EQ4), IOLD_LISMF (Q723S8), IOLD_LISMO (Q8Y9Y1), KDC_MYCLE (Q9CBD6), KDC_MYCS2 (A0R480), OXC_ECO57 (P0AFI1), OXC_ECOLI (P0AFI0), OXC_OXAFO (P40149), PDC1_MAIZE (P28516), PDC1_ORYSI (A2Y5L9), PDC1_ORYSJ (Q0DHF6), PDC1_PEA(P51850), PDC1_SCHPO (Q09737), PDC2_ARATH (Q9FFT4), PDC2_ORYSI (A2XFI3), PDC2_ORYSJ (Q10MW3), PDC2_TOBAC (P51846), PDC3_ORYSI (A2YQ76), PDC3_ORYSJ (Q0D3D2), PDC4_SCHPO (O42873), PDC_ASPFU (Q4WXX9), PDC_ASPOR (Q2UKV4), PDC_ASPPA (P51844), PDC_ASPTN (Q0CNV1), PDC_EMENI (P87208), PDC_HANUV (P34734), PHK1_LACPL (Q88U67), PHK1_NOSS1 (Q8YWW1), PHK1_RHIME (Q92T74), PHK2_LACPL (Q88S87), PHK2_NOSS1 (Q8YTZ6), PHK2_RHIME (Q92ZA4), PHK_BEII9 (B2IGR2), PHK_BIFA0 (B8DUT6), PHK_BRADU (Q89S87), PHK_BRUA2 (Q2YK44), PHK_BRUME (Q8YBL8), PHK_BRUSU (Q8FWR0), PHK_CHLTE (Q8KCA0), PHK_CLOAB (Q97JE3), PHK_GLOVI (Q7NLX2), PHK_LACLA (Q9CFH4), PHK_LATSS (Q38YY6), PHK_METCA (Q608B0), PHK_MYCA1 (A0QGK3), PHK_MYCPA (Q73ZM8), PHK_NITEU (Q82T07), PHK_NITMU (Q2YAC5), PHK_NOCFA (Q5Z066), PHK_PARUW (Q6MFC0), PHK_PEDPA (Q03H73), PHK_PSEP1 (A5W384), PHK_RHILO (Q988V7), PHK_RHOBA (Q7UH14), PHK_RHOP2 (Q2ITA9), PHK_RHOPA (Q6N976), PHK_RHOPB (Q20ZU5), PHK_RHOPS (Q13B10), PHK_RHOPT (B3Q8J5), PHK_SCHPO (O74770), PHK_STRAW (Q82NM9), PHK_STRCO (Q8CK51), PHK_SYNE7 (Q31LF9), PHK_SYNP6 (Q5N0G7), PHK_SYNY3 (P74690), PHK_THEVB (Q8DJN6), PIGD_SERMA (Q5W251), PIGD_SERS3 (Q5W268), PPD_STRHY (Q54271), PPD_STRVT (O86938), XFP_BIFAS (Q9AEM9), XPKA_LACPE (Q937F6), XSC_ALCXX (Q84H41), XSC_CASDE (Q84H44)» more |
| UniProtKB/Swiss-Prot 'Partial' sequences |
5 sequences
ILVB_ARTPT (P27868), PDC1_TOBAC (P51845), PDC2_MAIZE (Q05326), PDC2_PEA(P51851), PDC3_MAIZE (Q05327)» more |
| UniProtKB/Swiss-Prot False positive sequences |
7 sequences
COLB_DICDI (Q8T2A1), DXS1_CERS4 (Q3J1A8), DXS1_ROSDO (Q16DV7), DXS_FUSNN (Q8R639), DXS_RHOCA (P26242), ISOA2_ORYSJ (Q6AU80), NPHN_MOUSE (Q9QZS7)» more |
| PDB [Detailed view] |
131 PDB
1BFD; 1JSC; 1MCZ; 1N0H; 1OVM; 1OZF; 1OZG; 1OZH; 1PI3; 1PO7; 1POW; 1POX; 1PVD; 1PYD; 1Q6Z; 1QPB; 1T9A; 1T9B; 1T9C; 1T9D; 1UPA; 1UPB; 1UPC; 1Y9D; 1YBH; 1YHY; 1YHZ; 1YI0; 1YI1; 1YNO; 1Z8N; 1ZPD; 2EZ4; 2EZ8; 2EZ9; 2EZT; 2EZU; 2FN3; 2FWN; 2IHT; 2IHU; 2IHV; 2V3W; 2VJY; 2VK1; 2VK4; 2VK8; 2W93; 2WVA; 2WVG; 2WVH; 3E9Y; 3EA4; 3EY9; 3EYA; 3F6B; 3F6E; 3FSJ; 3FZN; 3OE1; 4GG1; 4GM0; 4GM1; 4GM4; 4GP9; 4GPE; 4JD5; 4JU8; 4JU9; 4JUA; 4JUB; 4JUC; 4JUD; 4JUF; 4K9K; 4K9L; 4K9M; 4K9N; 4K9O; 4K9P; 4MPJ; 4MPP; 4MPR; 4MQ5; 4MZX; 4QEL; 4ZP1; 5D6R; 5DEI; 5DGD; 5DGT; 5DX6; 5FEM; 5IMS; 5K2O; 5K3S; 5K6Q; 5K6R; 5K6T; 5TMA; 5WDG; 5WJ1; 5WKC; 6BD3; 6BD9; 6EFG; 6EFH; 6HAF; 6LPI; 6M2Y; 6M2Z; 6U9D; 6U9H; 6VZ8; 7PT1; 7PT2; 7PT3; 7PT4; 7STQ; 7TZZ; 7U1D; 7U1U; 7U25; 8ET4; 8ET5; 8XBO; 8XBQ; 8XBR; 9C4P; 9C4Q; 9C4R » more |