PROSITE logo

PROSITE entry PS00195


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] GLUTAREDOXIN_1
Accession [info] PS00195
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00173

Name and characterization of the entry

Description [info] Glutaredoxin active site.
Pattern [info] 
[LIVMD]-[FYSA]-x(4)-C-[PV]-[FYWH]-C-x(2)-[TAV]-x(2,3)-[LIV].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 73 in 73 different sequences
Number of true positive hits 70 in 70 different sequences
Number of 'unknown' hits 0
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 40
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 95.89 %
Recall (true positives / (true positives + false negatives)) 63.64 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] disulfide at position 4
Site [info] disulfide at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 70 sequences 

GLRX1_BOVIN (P10575), GLRX1_CAMPM (Q8V2V1), GLRX1_CAMPS (Q775X4), 

GLRX1_CHICK (P79764), GLRX1_CWPXB (Q8QMY9), GLRX1_CWPXG (Q80E01), 
GLRX1_ECOLI (P68688), GLRX1_ECTVM (Q8JLF5), GLRX1_HUMAN (P35754), 
GLRX1_MONPV (A0A7H0DN48), GLRX1_MOUSE (Q9QUH0), GLRX1_PIG   (P12309), 
GLRX1_RABIT (P12864), GLRX1_RABPU (Q6RZN3), GLRX1_RAT   (Q9ESH6), 
GLRX1_RHIID (B7ZFT1), GLRX1_RICBR (Q1RHJ0), GLRX1_RICCN (Q92J02), 
GLRX1_RICFE (Q4UKL7), GLRX1_RICPR (Q9ZDW1), GLRX1_RICTY (Q68XG4), 
GLRX1_SALTI (P0A1P9), GLRX1_SALTY (P0A1P8), GLRX1_SCHPO (O36032), 
GLRX1_SHIFL (P68689), GLRX1_SYNY3 (P74593), GLRX1_VACCA (Q76ZV3), 
GLRX1_VACCC (P68690), GLRX1_VACCP (P68691), GLRX1_VACCT (Q77TL9), 
GLRX1_VACCW (P68692), GLRX1_VAR67 (P0DOQ9), GLRX1_VARV  (P0DOR0), 
GLRX1_YEAST (P25373), GLRX2_ECO57 (P0AC61), GLRX2_ECOL6 (P0AC60), 
GLRX2_ECOLI (P0AC59), GLRX2_SCHPO (Q9UTI2), GLRX2_SYNY3 (P73492), 
GLRX2_YEAST (P17695), GLRX3_ECO57 (P0AC64), GLRX3_ECOL6 (P0AC63), 
GLRX3_ECOLI (P0AC62), GLRX_BPT4   (P00276), GLRX_DICDI  (Q54GP8), 
GLRX_HAEIN  (P45242), GLRX_MIMIV  (Q5UQ14), GLRX_NEIMA  (Q9JVU9), 
GLRX_NEIMB  (Q9JY15), GLRX_PSEAE  (Q9HU55), GLRX_RICCO  (P55143), 
GLRX_SOLLC  (Q9ZR41), GLRX_VERFO  (O81187), GRXC2_ARATH (Q9FNE2), 
GRXC4_ARATH (Q8LFQ6), GRXC4_ORYSJ (Q6K953), GRXC6_ORYSJ (P55142), 
GRXC8_ORYSJ (Q0DAE4), GSPRX_MARGR (B3EWI1), PGES2_BOVIN (Q66LN0), 
PGES2_DANRE (Q7ZUC7), PGES2_HUMAN (Q9H7Z7), PGES2_MACFA (Q9N0A4), 
PGES2_MOUSE (Q8BWM0), PRX5_HAEIN  (P44758), THIO_ARCFU  (O28137), 
THIO_METJA  (Q57755), THIO_METTH  (O26898), THIO_METTM  (P42035), 
YRUB_CLOPA  (P23171)
» more

UniProtKB/Swiss-Prot
False negative sequences		 40 sequences 

CMOI_BACSU  (O34639), GLRX2_BOVIN (Q32L67), GLRX2_HUMAN (Q9NS18), 

GLRX2_MOUSE (Q923X4), GLRX2_PONAB (Q5RC53), GLRX2_RAT   (Q6AXW1), 
GLRX8_YEAST (Q05926), GLRX_ENCCU  (Q8SUM8), GLRX_VIBCH  (Q9KSW0), 
GRC10_ARATH (Q29PZ1), GRC10_ORYSJ (Q2R076), GRC11_ARATH (Q9LYC6), 
GRC11_ORYSJ (Q2R075), GRC12_ARATH (O82254), GRC12_ORYSJ (Q2R073), 
GRC13_ARATH (O82255), GRC13_ORYSJ (Q0IRB0), GRC14_ARATH (Q9LYC5), 
GRC14_ORYSJ (Q0IMV4), GRC15_ORYSJ (Q2QP86), GRCR1_DROME (Q9VNL4), 
GRCR1_HUMAN (A8MXD5), GRCR1_MOUSE (Q50H32), GRCR2_DROME (Q9W4S1), 
GRXC1_ARATH (Q8L8T2), GRXC1_ORYSJ (Q7G8Y5), GRXC2_ORYSJ (Q0JG89), 
GRXC3_ARATH (Q9FVX1), GRXC3_ORYSJ (Q6K609), GRXC5_ARATH (Q8GWS0), 
GRXC5_ORYSJ (Q0JDM4), GRXC6_ARATH (Q8L9S3), GRXC7_ARATH (Q96305), 
GRXC7_ORYSJ (Q0DK35), GRXC8_ARATH (Q8LF89), GRXC9_ARATH (Q9SGP6), 
GRXC9_ORYSJ (Q7XIZ1), TRXR1_HUMAN (Q16881), TRXR3_HUMAN (Q86VQ6), 
TRXR3_MOUSE (Q99MD6)
» more

UniProtKB/Swiss-Prot
False positive sequences		 3 sequences 

NUON_CAMC1  (A7ZBF3), SIP5_PICGU  (A5DQJ8), Y3476_BRADU (Q89PK4)


				
	

	

		PDB
[Detailed view]		
		
			32 PDB
			


			1AAZ; 1DE1; 1DE2; 1EGO; 1EGR; 1FO5; 1FOV; 1G7O; 1JHB; 1KTE; 1NHO; 1NM3; 
			
				1Z9H; 2HZE; 2HZF; 2PBJ; 3C1R; 3C1S; 3CTF; 3CTG; 3D4M; 3QMX; 4KX4; 4MJA; 
				4MJB; 4MJC; 4MJE; 4RQR; 6MWS; 7D9L; 7DKP; 7DKR
			
			

			» more