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PROSITE entry PS00243


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PURL: https://purl.expasy.org/prosite/signature/PS00243

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General information about the entry

Entry name [info] I_EGF_1
Accession [info] PS00243
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-1990 DATA UPDATE;
27-NOV-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00216

Name and characterization of the entry

Description [info] Integrins beta chain EGF (I-EGF) domain signature.
Pattern [info] 
C-x-[GNQ]-x(1,3)-G-x-C-x-C-x(2)-C-x-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 155 in 51 different sequences
Number of true positive hits 154 in 50 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 99.35 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 10
Site [info] disulfide(?) at position 1
Site [info] disulfide(?) at position 7
Site [info] disulfide(?) at position 9
Site [info] disulfide(?) at position 11
Site [info] disulfide(?) at position 13
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 50 sequences 

ITB1A_XENLA (P12606), ITB1B_XENLA (P12607), ITB1_BOVIN  (P53712), 

ITB1_CAMBA  (A5Z1X6), ITB1_CHICK  (P07228), ITB1_FELCA  (P53713), 
ITB1_HUMAN  (P05556), ITB1_MOUSE  (P09055), ITB1_PIG(Q9GLP0), 
ITB1_PONAB  (Q5RCA9), ITB1_RAT(P49134), ITB1_SHEEP  (B0FYY4), 
ITB2L_MOUSE (Q3UV74), ITB2_BOVIN  (P32592), ITB2_CAPHI  (Q5VI41), 
ITB2_HUMAN  (P05107), ITB2_MOUSE  (P11835), ITB2_OVICA  (Q2VJ42), 
ITB2_PIG(P53714), ITB2_SHEEP  (Q6ECI6), ITB3_HUMAN  (P05106), 
ITB3_MOUSE  (O54890), ITB3_RAT(Q8R2H2), ITB4_HUMAN  (P16144), 
ITB4_MOUSE  (A2A863), ITB4_RAT(Q64632), ITB5_BOVIN  (P80747), 
ITB5_HUMAN  (P18084), ITB5_MOUSE  (O70309), ITB5_PAPCY  (Q07441), 
ITB6_BOVIN  (Q8SQB8), ITB6_CAVPO  (P18563), ITB6_HUMAN  (P18564), 
ITB6_MOUSE  (Q9Z0T9), ITB6_PIG(Q1RPR6), ITB6_RAT(Q6AYF4), 
ITB6_SHEEP  (Q863C4), ITB7_HUMAN  (P26010), ITB7_MOUSE  (P26011), 
ITB8_HUMAN  (P26012), ITB8_MOUSE  (Q0VBD0), ITB8_RABIT  (P26013), 
ITBL_CAEEL  (Q9GYK2), ITBN_DROME  (Q27591), ITBX_DROME  (P11584), 
ITGBL_HUMAN (O95965), ITGBL_MOUSE (Q8VDV0), ITGBL_RAT   (Q5PQQ8), 
ITGBL_XENLA (Q5M9B3), PAT3_CAEEL  (Q27874)
» more

UniProtKB/Swiss-Prot
False positive sequences		 1 sequence 

C30_CONCL   (P0DTX8)


				
	

	

		PDB
[Detailed view]		
		
			68 PDB
			


			1JV2; 1L3Y; 1L5G; 1M1X; 1U8C; 2P26; 2P28; 3FCS; 3IJE; 3K6S; 3K71; 3K72; 
			
				4CAK; 4G1E; 4G1M; 4MMX; 4MMY; 4MMZ; 4NEH; 4NEN; 4O02; 4UM8; 5E6W; 5E6X; 
				5ES4; 6AVQ; 6AVR; 6AVU; 6BXB; 6BXF; 6BXJ; 6CKB; 6DJP; 6MK0; 6MSL; 6MSU; 
				6NAJ; 6UJA; 6UJB; 6UJC; 6V4P; 7LA4; 7NWL; 7NXD; 7USL; 7USM; 8GCD; 8GCE; 
				8OXZ; 8T2U; 8T2V; 8VS6; 8XEI; 8XEK; 8XEL; 8XEN; 8XER; 8XEZ; 8XF6; 8XFG; 
				8XFO; 8ZJF; 9AXL; 9B9J; 9B9K; 9CKV; 9DEQ; 9DER
			
			

			» more