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PROSITE entry PS00247


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PURL: https://purl.expasy.org/prosite/signature/PS00247

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General information about the entry

Entry name [info] HBGF_FGF
Accession [info] PS00247
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00220

Name and characterization of the entry

Description [info] HBGF/FGF family signature.
Pattern [info] 
G-x-[LIM]-x-[STAGP]-x(6,7)-[DENA]-C-x-[FLM]-x-[EQ]-x(6)-Y.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 103 in 103 different sequences
Number of true positive hits 103 in 103 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 4
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 96.26 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 103 sequences 

FG17_DANRE  (Q6SJP8), FGF10_HUMAN (O15520), FGF10_MOUSE (O35565), 

FGF10_RAT   (P70492), FGF11_HUMAN (Q92914), FGF11_MOUSE (P70378), 
FGF12_HUMAN (P61328), FGF12_MOUSE (P61329), FGF12_RAT   (P61150), 
FGF13_HUMAN (Q92913), FGF13_MOUSE (P70377), FGF13_PONAB (Q5RDS9), 
FGF13_RAT   (Q9ERW3), FGF13_XENLA (A6P7H6), FGF14_HUMAN (Q92915), 
FGF14_MOUSE (P70379), FGF14_RAT   (Q8R5L7), FGF15_MOUSE (O35622), 
FGF16_DANRE (Q2HXK8), FGF16_HUMAN (O43320), FGF16_MOUSE (Q9ESL8), 
FGF16_RAT   (O54769), FGF17_HUMAN (O60258), FGF17_MOUSE (P63075), 
FGF17_RAT   (P63076), FGF18_BOVIN (Q0VCA0), FGF18_HUMAN (O76093), 
FGF18_MOUSE (O89101), FGF18_RAT   (O88182), FGF19_HUMAN (O95750), 
FGF1_BOVIN  (P03968), FGF1_CAPCA  (Q9N1S8), FGF1_CHICK  (P19596), 
FGF1_CYNPY  (Q6I6M7), FGF1_HUMAN  (P05230), FGF1_MESAU  (P34004), 
FGF1_MOUSE  (P61148), FGF1_NOTVI  (Q7SIF8), FGF1_PIG(P20002), 
FGF1_PONAB  (Q5NVQ3), FGF1_RAT(P61149), FGF1_SHEEP  (Q7M303), 
FGF1_XENLA  (Q6GLR6), FGF20_HUMAN (Q9NP95), FGF20_MOUSE (Q9ESL9), 
FGF20_RAT   (Q9EST9), FGF21_HUMAN (Q9NSA1), FGF21_MOUSE (Q9JJN1), 
FGF22_MOUSE (Q9ESS2), FGF23_MOUSE (Q9EPC2), FGF23_RAT   (Q8VI82), 
FGF2_BOVIN  (P03969), FGF2_CAVPO  (Q60487), FGF2_CHICK  (P48800), 
FGF2_HUMAN  (P09038), FGF2_MONDO  (P48798), FGF2_MOUSE  (P15655), 
FGF2_PANTR  (Q5IS69), FGF2_RABIT  (P48799), FGF2_RAT(P13109), 
FGF2_SHEEP  (P20003), FGF2_XENLA  (P12226), FGF3_CHICK  (P48801), 
FGF3_DANRE  (P48802), FGF3_HUMAN  (P11487), FGF3_MOUSE  (P05524), 
FGF3_XENLA  (P36386), FGF4A_XENLA (P48805), FGF4B_XENLA (P48806), 
FGF4_BOVIN  (P48803), FGF4_CHICK  (P48804), FGF4_HUMAN  (P08620), 
FGF4_MOUSE  (P11403), FGF5_BOVIN  (A0MTF4), FGF5_CANLF  (Q20FD0), 
FGF5_FELCA  (M3X9S6), FGF5_HUMAN  (P12034), FGF5_MOUSE  (P15656), 
FGF5_RAT(P48807), FGF6_HUMAN  (P10767), FGF6_MOUSE  (P21658), 
FGF7_CANLF  (P79150), FGF7_CEREL  (Q5D0X0), FGF7_HUMAN  (P21781), 
FGF7_MOUSE  (P36363), FGF7_PIG(Q9N198), FGF7_PONAB  (Q5RAY8), 
FGF7_RAT(Q02195), FGF7_SHEEP  (P48808), FGF8A_DANRE (O57341), 
FGF8B_DANRE (Q805B2), FGF8_CANLF  (O62682), FGF8_CHICK  (Q90722), 
FGF8_HUMAN  (P55075), FGF8_MOUSE  (P37237), FGF9_DIDAL  (Q3ZFI5), 
FGF9_HUMAN  (P31371), FGF9_MOUSE  (P54130), FGF9_PIG(Q95L12), 
FGF9_RAT(P36364), FGF9_XENLA  (Q91875), FGFH_NPVAC  (P41444), 
FGFH_NPVOP  (O10284)
» more

UniProtKB/Swiss-Prot
False negative sequences		 4 sequences 

FGF22_HUMAN (Q9HCT0), FGF23_HUMAN (Q9GZV9), FGF23_TETNG (Q5MK86), 

LE756_CAEEL (Q11184)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

FGF1_CANLF  (P18651)


				
	

	

		PDB
[Detailed view]		
		
			133 PDB
			


			1AFC; 1AXM; 1BAR; 1BAS; 1BFB; 1BFC; 1BFF; 1BFG; 1BLA; 1BLD; 1CVS; 1DJS; 
			
				1DZC; 1DZD; 1E0O; 1EV2; 1EVT; 1FGA; 1FMM; 1FQ9; 1G82; 1HKN; 1IHK; 1II4; 
				1IIL; 1IJT; 1JQZ; 1JT4; 1JTC; 1JY0; 1K5U; 1K5V; 1NUN; 1P63; 1PWA; 1PZZ; 
				1Q03; 1Q04; 1Q1U; 1QQK; 1QQL; 1RG8; 1RML; 1RY7; 1YTO; 1Z2V; 1Z4S; 2AFG; 
				2AQZ; 2AXM; 2BFH; 2ERM; 2FDB; 2FGF; 2HW9; 2HWA; 2HWM; 2HZ9; 2J3P; 2K43; 
				2K4A; 2K8R; 2KI4; 2KI6; 2M49; 2NTD; 2P23; 2Q9X; 2RQ9; 2UUS; 3B9U; 3BA4; 
				3BA5; 3BA7; 3BAD; 3BAG; 3BAH; 3BAO; 3BAQ; 3BAU; 3BAV; 3BB2; 3CQA; 3CRG; 
				3CRH; 3CRI; 3CU1; 3F1R; 3FJ8; 3FJA; 3FJB; 3FJC; 3FJD; 3FJK; 3HBW; 3HOM; 
				3JUT; 3K1X; 3OJ2; 3OJM; 3OJV; 3UD7; 3UD8; 3UD9; 3UDA; 4CJM; 4DCK; 4FGF; 
				4J23; 4JPZ; 4JQ0; 4OEE; 4OEF; 4OEG; 4Q91; 4Q9G; 4Q9P; 4QAL; 4QBC; 4QBV; 
				4QC4; 4QO3; 4XKI; 4YOL; 5W59; 5X1O; 6KTR; 6L4O; 6M6E; 6M6F; 8HU7; 8HUE; 
				8OM6
			
			

			» more