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PROSITE entry PS00247


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PURL: https://purl.expasy.org/prosite/signature/PS00247

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General information about the entry

Entry name [info] HBGF_FGF
Accession [info] PS00247
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00220

Name and characterization of the entry

Description [info] HBGF/FGF family signature.
Pattern [info] 
G-x-[LIM]-x-[STAGP]-x(6,7)-[DENA]-C-x-[FLM]-x-[EQ]-x(6)-Y.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 103 in 103 different sequences
Number of true positive hits 103 in 103 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 4
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 96.26 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 103 sequences 

FG17_DANRE  (Q6SJP8), FGF10_HUMAN (O15520), FGF10_MOUSE (O35565), 

FGF10_RAT   (P70492), FGF11_HUMAN (Q92914), FGF11_MOUSE (P70378), 
FGF12_HUMAN (P61328), FGF12_MOUSE (P61329), FGF12_RAT   (P61150), 
FGF13_HUMAN (Q92913), FGF13_MOUSE (P70377), FGF13_PONAB (Q5RDS9), 
FGF13_RAT   (Q9ERW3), FGF13_XENLA (A6P7H6), FGF14_HUMAN (Q92915), 
FGF14_MOUSE (P70379), FGF14_RAT   (Q8R5L7), FGF15_MOUSE (O35622), 
FGF16_DANRE (Q2HXK8), FGF16_HUMAN (O43320), FGF16_MOUSE (Q9ESL8), 
FGF16_RAT   (O54769), FGF17_HUMAN (O60258), FGF17_MOUSE (P63075), 
FGF17_RAT   (P63076), FGF18_BOVIN (Q0VCA0), FGF18_HUMAN (O76093), 
FGF18_MOUSE (O89101), FGF18_RAT   (O88182), FGF19_HUMAN (O95750), 
FGF1_BOVIN  (P03968), FGF1_CAPCA  (Q9N1S8), FGF1_CHICK  (P19596), 
FGF1_CYNPY  (Q6I6M7), FGF1_HUMAN  (P05230), FGF1_MESAU  (P34004), 
FGF1_MOUSE  (P61148), FGF1_NOTVI  (Q7SIF8), FGF1_PIG(P20002), 
FGF1_PONAB  (Q5NVQ3), FGF1_RAT(P61149), FGF1_SHEEP  (Q7M303), 
FGF1_XENLA  (Q6GLR6), FGF20_HUMAN (Q9NP95), FGF20_MOUSE (Q9ESL9), 
FGF20_RAT   (Q9EST9), FGF21_HUMAN (Q9NSA1), FGF21_MOUSE (Q9JJN1), 
FGF22_MOUSE (Q9ESS2), FGF23_MOUSE (Q9EPC2), FGF23_RAT   (Q8VI82), 
FGF2_BOVIN  (P03969), FGF2_CAVPO  (Q60487), FGF2_CHICK  (P48800), 
FGF2_HUMAN  (P09038), FGF2_MONDO  (P48798), FGF2_MOUSE  (P15655), 
FGF2_PANTR  (Q5IS69), FGF2_RABIT  (P48799), FGF2_RAT(P13109), 
FGF2_SHEEP  (P20003), FGF2_XENLA  (P12226), FGF3_CHICK  (P48801), 
FGF3_DANRE  (P48802), FGF3_HUMAN  (P11487), FGF3_MOUSE  (P05524), 
FGF3_XENLA  (P36386), FGF4A_XENLA (P48805), FGF4B_XENLA (P48806), 
FGF4_BOVIN  (P48803), FGF4_CHICK  (P48804), FGF4_HUMAN  (P08620), 
FGF4_MOUSE  (P11403), FGF5_BOVIN  (A0MTF4), FGF5_CANLF  (Q20FD0), 
FGF5_FELCA  (M3X9S6), FGF5_HUMAN  (P12034), FGF5_MOUSE  (P15656), 
FGF5_RAT(P48807), FGF6_HUMAN  (P10767), FGF6_MOUSE  (P21658), 
FGF7_CANLF  (P79150), FGF7_CEREL  (Q5D0X0), FGF7_HUMAN  (P21781), 
FGF7_MOUSE  (P36363), FGF7_PIG(Q9N198), FGF7_PONAB  (Q5RAY8), 
FGF7_RAT(Q02195), FGF7_SHEEP  (P48808), FGF8A_DANRE (O57341), 
FGF8B_DANRE (Q805B2), FGF8_CANLF  (O62682), FGF8_CHICK  (Q90722), 
FGF8_HUMAN  (P55075), FGF8_MOUSE  (P37237), FGF9_DIDAL  (Q3ZFI5), 
FGF9_HUMAN  (P31371), FGF9_MOUSE  (P54130), FGF9_PIG(Q95L12), 
FGF9_RAT(P36364), FGF9_XENLA  (Q91875), FGFH_NPVAC  (P41444), 
FGFH_NPVOP  (O10284)
» more

UniProtKB/Swiss-Prot
False negative sequences		 4 sequences 

FGF22_HUMAN (Q9HCT0), FGF23_HUMAN (Q9GZV9), FGF23_TETNG (Q5MK86), 

LE756_CAEEL (Q11184)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

FGF1_CANLF  (P18651)


				
	

	

		PDB
[Detailed view]		
		
			133 PDB
			


			pdb_00001afc; pdb_00001axm; pdb_00001bar; pdb_00001bas; pdb_00001bfb; pdb_00001bfc; pdb_00001bff; pdb_00001bfg; pdb_00001bla; pdb_00001bld; pdb_00001cvs; pdb_00001djs; 
			
				pdb_00001dzc; pdb_00001dzd; pdb_00001e0o; pdb_00001ev2; pdb_00001evt; pdb_00001fga; pdb_00001fmm; pdb_00001fq9; pdb_00001g82; pdb_00001hkn; pdb_00001ihk; pdb_00001ii4; 
				pdb_00001iil; pdb_00001ijt; pdb_00001jqz; pdb_00001jt4; pdb_00001jtc; pdb_00001jy0; pdb_00001k5u; pdb_00001k5v; pdb_00001nun; pdb_00001p63; pdb_00001pwa; pdb_00001pzz; 
				pdb_00001q03; pdb_00001q04; pdb_00001q1u; pdb_00001qqk; pdb_00001qql; pdb_00001rg8; pdb_00001rml; pdb_00001ry7; pdb_00001yto; pdb_00001z2v; pdb_00001z4s; pdb_00002afg; 
				pdb_00002aqz; pdb_00002axm; pdb_00002bfh; pdb_00002erm; pdb_00002fdb; pdb_00002fgf; pdb_00002hw9; pdb_00002hwa; pdb_00002hwm; pdb_00002hz9; pdb_00002j3p; pdb_00002k43; 
				pdb_00002k4a; pdb_00002k8r; pdb_00002ki4; pdb_00002ki6; pdb_00002m49; pdb_00002ntd; pdb_00002p23; pdb_00002q9x; pdb_00002rq9; pdb_00002uus; pdb_00003b9u; pdb_00003ba4; 
				pdb_00003ba5; pdb_00003ba7; pdb_00003bad; pdb_00003bag; pdb_00003bah; pdb_00003bao; pdb_00003baq; pdb_00003bau; pdb_00003bav; pdb_00003bb2; pdb_00003cqa; pdb_00003crg; 
				pdb_00003crh; pdb_00003cri; pdb_00003cu1; pdb_00003f1r; pdb_00003fj8; pdb_00003fja; pdb_00003fjb; pdb_00003fjc; pdb_00003fjd; pdb_00003fjk; pdb_00003hbw; pdb_00003hom; 
				pdb_00003jut; pdb_00003k1x; pdb_00003oj2; pdb_00003ojm; pdb_00003ojv; pdb_00003ud7; pdb_00003ud8; pdb_00003ud9; pdb_00003uda; pdb_00004cjm; pdb_00004dck; pdb_00004fgf; 
				pdb_00004j23; pdb_00004jpz; pdb_00004jq0; pdb_00004oee; pdb_00004oef; pdb_00004oeg; pdb_00004q91; pdb_00004q9g; pdb_00004q9p; pdb_00004qal; pdb_00004qbc; pdb_00004qbv; 
				pdb_00004qc4; pdb_00004qo3; pdb_00004xki; pdb_00004yol; pdb_00005w59; pdb_00005x1o; pdb_00006ktr; pdb_00006l4o; pdb_00006m6e; pdb_00006m6f; pdb_00008hu7; pdb_00008hue; 
				pdb_00008om6
			
			

			» more