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PROSITE entry PS00249


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PURL: https://purl.expasy.org/prosite/signature/PS00249

Direct ScanProsite submission
General information about the entry

Entry name [info] PDGF_1
Accession [info] PS00249
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00222

Name and characterization of the entry

Description [info] Platelet-derived growth factor (PDGF) family signature.
Pattern [info] 
P-[PSR]-C-V-x(3)-R-C-[GSTA]-G-C-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 63 in 63 different sequences
Number of true positive hits 63 in 63 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 10
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 86.30 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] disulfide at position 3
Site [info] disulfide at position 7
Site [info] disulfide at position 10
Site [info] disulfide at position 11
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 63 sequences 

PDGFA_BOVIN (Q2KJ15), PDGFA_HUMAN (P04085), PDGFA_MOUSE (P20033), 

PDGFA_RABIT (P34007), PDGFA_RAT   (P28576), PDGFA_XENLA (P13698), 
PDGFB_CANLF (Q6Q7I7), PDGFB_FELCA (P12919), PDGFB_HUMAN (P01127), 
PDGFB_MOUSE (P31240), PDGFB_RAT   (Q05028), PDGFB_SHEEP (Q95229), 
PLGF_BOVIN  (Q9XS47), PLGF_HUMAN  (P49763), PLGF_MOUSE  (P49764), 
PLGF_RAT(Q63434), TSIS_WMSV   (P01128), TXVE1_SISCA (B0VXV3), 
TXVE2_MACLB (P82475), TXVE2_PROMU (Q330K6), TXVE_AGKPI  (C0K3N2), 
TXVE_BITAR  (C0K3N1), TXVE_BOTER  (Q6J936), TXVE_BOTIN  (Q90X24), 
TXVE_BOTJA  (Q90X23), TXVE_CROAT  (C0K3N3), TXVE_DABPA  (P0DW97), 
TXVE_DABRR  (P67861), TXVE_DABSI  (P0DL42), TXVE_PROFL  (P67862), 
TXVE_PROJR  (P0DW98), TXVE_SISCA  (B0VXV4), TXVE_VIPAA  (P67863), 
TXVE_VIPAP  (P83942), VEGFA_AGKPI (C0K3N4), VEGFA_BITGA (P83906), 
VEGFA_BOVIN (P15691), VEGFA_CANLF (Q9MYV3), VEGFA_CAVPO (P26617), 
VEGFA_CHICK (P67964), VEGFA_COTJA (P67965), VEGFA_HORSE (Q9GKR0), 
VEGFA_HUMAN (P15692), VEGFA_MESAU (Q99PS1), VEGFA_MOUSE (Q00731), 
VEGFA_PIG   (P49151), VEGFA_PROFL (P67860), VEGFA_RAT   (P16612), 
VEGFA_SHEEP (P50412), VEGFA_VIPAA (C0K3N5), VEGFB_BOVIN (Q9XS49), 
VEGFB_HUMAN (P49765), VEGFB_MOUSE (P49766), VEGFB_RAT   (O35485), 
VEGFC_HUMAN (P49767), VEGFC_MOUSE (P97953), VEGFC_RAT   (O35757), 
VEGFD_HUMAN (O43915), VEGFD_MOUSE (P97946), VEGFD_RAT   (O35251), 
VEGFH_ORFN2 (P52584), VEGFH_ORFN7 (P52585), VGFAA_DANRE (O73682)
» more

UniProtKB/Swiss-Prot
False negative sequences		 10 sequences 

PDGFC_CHICK (Q9I946), PDGFC_GEKJA (A8WCC4), PDGFC_HUMAN (Q9NRA1), 

PDGFC_MOUSE (Q8CI19), PDGFC_RAT   (Q9EQX6), PDGFD_HUMAN (Q9GZP0), 
PDGFD_MOUSE (Q925I7), PDGFD_PONAB (Q5RA73), PDGFD_RABIT (Q6V9H4), 
PDGFD_RAT   (Q9EQT1)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

PDGFB_PIG   (P20034)


				
	

	

		PDB
[Detailed view]		
		
			68 PDB
			


			pdb_00001bj1; pdb_00001cz8; pdb_00001flt; pdb_00001fzv; pdb_00001kat; pdb_00001pdg; pdb_00001qty; pdb_00001rv6; pdb_00001tzh; pdb_00001tzi; pdb_00001vpf; pdb_00001vpp; 
			
				pdb_00001wq8; pdb_00001wq9; pdb_00002c7w; pdb_00002fjg; pdb_00002fjh; pdb_00002gnn; pdb_00002qr0; pdb_00002vpf; pdb_00002vwe; pdb_00002x1w; pdb_00002x1x; pdb_00002xac; 
				pdb_00002xv7; pdb_00003bdy; pdb_00003mjg; pdb_00003mjk; pdb_00003p9w; pdb_00003qtk; pdb_00003s1b; pdb_00003s1k; pdb_00003v2a; pdb_00003v6b; pdb_00004bsk; pdb_00004gln; 
				pdb_00004gls; pdb_00004hqu; pdb_00004hqx; pdb_00004kzn; pdb_00004qaf; pdb_00004qci; pdb_00004wpb; pdb_00004zff; pdb_00005fv1; pdb_00005fv2; pdb_00005hhc; pdb_00005hhd; 
				pdb_00005o4e; pdb_00005t89; pdb_00006bft; pdb_00006d3o; pdb_00006t9d; pdb_00006t9e; pdb_00006v7k; pdb_00006z13; pdb_00006z3f; pdb_00006zbr; pdb_00006zcd; pdb_00006zfl; 
				pdb_00007kez; pdb_00007kf0; pdb_00007kf1; pdb_00007ll8; pdb_00007ll9; pdb_00008uwz; pdb_00009ju1; pdb_00009kku
			
			

			» more