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PROSITE entry PS00249


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General information about the entry

Entry name [info] PDGF_1
Accession [info] PS00249
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00222

Name and characterization of the entry

Description [info] Platelet-derived growth factor (PDGF) family signature.
Pattern [info] 
P-[PSR]-C-V-x(3)-R-C-[GSTA]-G-C-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.


Total number of hits 63 in 63 different sequences
Number of true positive hits 63 in 63 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 10
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 86.30 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] disulfide at position 3
Site [info] disulfide at position 7
Site [info] disulfide at position 10
Site [info] disulfide at position 11
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 63 sequences 

PDGFA_BOVIN (Q2KJ15), PDGFA_HUMAN (P04085), PDGFA_MOUSE (P20033), 

PDGFA_RABIT (P34007), PDGFA_RAT   (P28576), PDGFA_XENLA (P13698), 
PDGFB_CANLF (Q6Q7I7), PDGFB_FELCA (P12919), PDGFB_HUMAN (P01127), 
PDGFB_MOUSE (P31240), PDGFB_RAT   (Q05028), PDGFB_SHEEP (Q95229), 
PLGF_BOVIN  (Q9XS47), PLGF_HUMAN  (P49763), PLGF_MOUSE  (P49764), 
PLGF_RAT(Q63434), TSIS_WMSV   (P01128), TXVE1_SISCA (B0VXV3), 
TXVE2_MACLB (P82475), TXVE2_PROMU (Q330K6), TXVE_AGKPI  (C0K3N2), 
TXVE_BITAR  (C0K3N1), TXVE_BOTER  (Q6J936), TXVE_BOTIN  (Q90X24), 
TXVE_BOTJA  (Q90X23), TXVE_CROAT  (C0K3N3), TXVE_DABPA  (P0DW97), 
TXVE_DABRR  (P67861), TXVE_DABSI  (P0DL42), TXVE_PROFL  (P67862), 
TXVE_PROJR  (P0DW98), TXVE_SISCA  (B0VXV4), TXVE_VIPAA  (P67863), 
TXVE_VIPAP  (P83942), VEGFA_AGKPI (C0K3N4), VEGFA_BITGA (P83906), 
VEGFA_BOVIN (P15691), VEGFA_CANLF (Q9MYV3), VEGFA_CAVPO (P26617), 
VEGFA_CHICK (P67964), VEGFA_COTJA (P67965), VEGFA_HORSE (Q9GKR0), 
VEGFA_HUMAN (P15692), VEGFA_MESAU (Q99PS1), VEGFA_MOUSE (Q00731), 
VEGFA_PIG   (P49151), VEGFA_PROFL (P67860), VEGFA_RAT   (P16612), 
VEGFA_SHEEP (P50412), VEGFA_VIPAA (C0K3N5), VEGFB_BOVIN (Q9XS49), 
VEGFB_HUMAN (P49765), VEGFB_MOUSE (P49766), VEGFB_RAT   (O35485), 
VEGFC_HUMAN (P49767), VEGFC_MOUSE (P97953), VEGFC_RAT   (O35757), 
VEGFD_HUMAN (O43915), VEGFD_MOUSE (P97946), VEGFD_RAT   (O35251), 
VEGFH_ORFN2 (P52584), VEGFH_ORFN7 (P52585), VGFAA_DANRE (O73682)
» more

UniProtKB/Swiss-Prot
False negative sequences		 10 sequences 

PDGFC_CHICK (Q9I946), PDGFC_GEKJA (A8WCC4), PDGFC_HUMAN (Q9NRA1), 

PDGFC_MOUSE (Q8CI19), PDGFC_RAT   (Q9EQX6), PDGFD_HUMAN (Q9GZP0), 
PDGFD_MOUSE (Q925I7), PDGFD_PONAB (Q5RA73), PDGFD_RABIT (Q6V9H4), 
PDGFD_RAT   (Q9EQT1)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

PDGFB_PIG   (P20034)


				
	

	

		PDB
[Detailed view]		
		
			65 PDB
			


			1BJ1; 1CZ8; 1FLT; 1FZV; 1KAT; 1PDG; 1QTY; 1RV6; 1TZH; 1TZI; 1VPF; 1VPP; 
			
				1WQ8; 1WQ9; 2C7W; 2FJG; 2FJH; 2GNN; 2QR0; 2VPF; 2VWE; 2X1W; 2X1X; 2XAC; 
				2XV7; 3BDY; 3MJG; 3MJK; 3P9W; 3QTK; 3S1B; 3S1K; 3V2A; 3V6B; 4BSK; 4GLN; 
				4GLS; 4HQU; 4HQX; 4KZN; 4QAF; 4QCI; 4WPB; 4ZFF; 5FV1; 5FV2; 5HHC; 5HHD; 
				5O4E; 5T89; 6BFT; 6D3O; 6T9D; 6T9E; 6V7K; 6Z13; 6Z3F; 6ZBR; 6ZCD; 6ZFL; 
				7KEZ; 7KF0; 7KF1; 7LL8; 7LL9
			
			

			» more