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PROSITE entry PS00253


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00253
Entry name [info] INTERLEUKIN_1
Accession [info] PS00253
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00226

Name and characterization of the entry

Description [info] Interleukin-1 signature.
Pattern [info] 
[FC]-x-S-[ASLV]-x(2)-P-x(2)-[FYLIV]-[LI]-[SCA]-T-x(7)-[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 54 in 54 different sequences
Number of true positive hits 54 in 54 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 9
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 85.71 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 54 sequences 

I36RA_HUMAN (Q9UBH0), I36RA_MOUSE (Q9QYY1), IL1A_BOVIN  (P08831), 

IL1A_BUBCA  (Q3HWU1), IL1A_CANLF  (O46612), IL1A_CAPHI  (P79161), 
IL1A_CERAT  (P46647), IL1A_FELCA  (O46613), IL1A_HORSE  (Q28385), 
IL1A_HUMAN  (P01583), IL1A_LAMGL  (Q865X7), IL1A_MACFA  (P79340), 
IL1A_MACMU  (P48089), IL1A_MOUSE  (P01582), IL1A_PIG(P18430), 
IL1A_RABIT  (P04822), IL1A_RAT(P16598), IL1A_SHEEP  (Q28579), 
IL1B_BOVIN  (P09428), IL1B_BUBCA  (Q2MH07), IL1B_CANLF  (Q28292), 
IL1B_CAPHI  (P79162), IL1B_CAVPO  (Q9WVG1), IL1B_CERAT  (P46648), 
IL1B_CEREL  (P51745), IL1B_DELLE  (Q8WNR2), IL1B_EUMJU  (Q6R2X3), 
IL1B_FELCA  (P41687), IL1B_HORSE  (Q28386), IL1B_HUMAN  (P01584), 
IL1B_LAMGL  (Q865X8), IL1B_MACFA  (P79182), IL1B_MACMU  (P48090), 
IL1B_MACNE  (P51493), IL1B_MOUSE  (P10749), IL1B_MUSPF  (A4UYK8), 
IL1B_PHOVR  (Q6PUD2), IL1B_PIG(P26889), IL1B_PUSHI  (Q2HZH0), 
IL1B_RABIT  (P14628), IL1B_RAT(Q63264), IL1B_SHEEP  (P21621), 
IL1B_TRIVU  (Q9XS77), IL1RA_BOVIN (O77482), IL1RA_CANLF (Q9BEH0), 
IL1RA_HORSE (O18999), IL1RA_HUMAN (P18510), IL1RA_MACFA (Q866R8), 
IL1RA_MOUSE (P25085), IL1RA_PIG   (Q29056), IL1RA_RABIT (P26890), 
IL1RA_RAT   (P25086), IL1RA_TURTR (Q9GMZ4), IL36B_MOUSE (Q9D6Z6)
» more

UniProtKB/Swiss-Prot
False negative sequences		 9 sequences 

IL1B_ONCMY  (Q9YGD3), IL1FA_HUMAN (Q8WWZ1), IL1FA_MOUSE (Q8R459), 

IL36A_HUMAN (Q9UHA7), IL36A_MOUSE (Q9JLA2), IL36B_HUMAN (Q9NZH7), 
IL36G_HUMAN (Q9NZH8), IL36G_MOUSE (Q8R460), IL37_HUMAN  (Q9NZH6)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

IL1A_CAVPO  (Q60480)


				
	

	

		PDB
[Detailed view]		
		
			79 PDB
			


			1HIB; 1I1B; 1ILR; 1ILT; 1IOB; 1IRA; 1IRP; 1ITB; 1L2H; 1MD6; 1S0L; 1T4Q; 
			
				1TOO; 1TP0; 1TWE; 1TWM; 21BI; 2I1B; 2ILA; 2IRT; 2KH2; 2KKI; 2L5X; 2MIB; 
				2NVH; 31BI; 3LTQ; 3O4O; 3POK; 41BI; 4DEP; 4G6J; 4G6M; 4GAF; 4GAI; 4I1B; 
				4P0J; 4P0K; 4P0L; 5BVP; 5I1B; 5MVZ; 5R7W; 5R85; 5R86; 5R87; 5R88; 5R89; 
				5R8A; 5R8B; 5R8C; 5R8D; 5R8E; 5R8F; 5R8G; 5R8H; 5R8I; 5R8J; 5R8K; 5R8L; 
				5R8M; 5R8N; 5R8O; 5R8P; 5R8Q; 5UC6; 6I1B; 6Y8I; 6Y8M; 7CHY; 7CHZ; 7I1B; 
				7Z4T; 8C3U; 8I1B; 8RYK; 8RYS; 8RZB; 9ILB
			
			

			» more