PROSITE entry PS00254
View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission
General information about the entry
Entry name [info] | INTERLEUKIN_6 |
Accession [info] | PS00254 |
Entry type [info] | PATTERN |
Date [info] |
01-APR-1990 CREATED;
01-APR-1990 DATA UPDATE; 13-SEP-2023 INFO UPDATE. |
PROSITE Doc. [info] | PDOC00227 |
Name and characterization of the entry
Description [info] | Interleukin-6 / G-CSF / MGF signature. |
Pattern [info] |
C-x(9)-C-x(6)-G-L-x(2)-[FY]-x(3)-L. |
Numerical results [info]
Total number of hits | 39 in 39 different sequences |
Number of true positive hits | 37 in 37 different sequences |
Number of 'unknown' hits | 0 |
Number of false positive hits | 2 in 2 different sequences |
Number of false negative sequences | 3 |
Number of 'partial' sequences | 0 |
Precision (true positives / (true positives + false positives)) | 94.87 % |
Recall (true positives / (true positives + false negatives)) | 92.50 % |
Comments [info]
Taxonomic range [info] | Eukaryotes |
Maximum number of repetitions [info] | 1 |
Site [info] | disulfide at position 1 |
Site [info] | disulfide at position 3 |
Version [info] | 1 |
Cross-references [info]
UniProtKB/Swiss-Prot True positive sequences |
37 sequences
CSF3_BOVIN (P35833), CSF3_CANLF (P35834), CSF3_FELCA (O02708), CSF3_HUMAN (P09919), CSF3_MOUSE (P09920), CSF3_PIG(O02837), CSF3_SHEEP (Q28746), IL6_BOVIN (P26892), IL6_BUBBU (Q6V919), IL6_BUBCA (Q2MH06), IL6_CAMBA (Q865W7), IL6_CANLF (P41323), IL6_CAPHI (Q28319), IL6_CERAT (P46650), IL6_CHICK (Q90YI0), IL6_DELLE (Q9XT80), IL6_FELCA (P41683), IL6_HORSE (Q95181), IL6_HUMAN (P05231), IL6_LAMGL (Q865X6), IL6_MACFA (P79341), IL6_MACMU (P51494), IL6_MACTH (Q5I6E3), IL6_MARMO (O35736), IL6_MOUSE (P08505), IL6_MUSPF (A3FBE9), IL6_NEOVI (P41693), IL6_ORCOR (Q28747), IL6_PHOVI (Q28819), IL6_PIG (P26893), IL6_RABIT (Q9MZR1), IL6_RAT (P20607), IL6_SAISC (Q8MKH0), IL6_SHEEP (P29455), IL6_TAKRU (Q6L6X6), IL6_VULVU (Q25BC2), MGF_CHICK (P13854)» more
|
UniProtKB/Swiss-Prot False negative sequences |
3 sequences
IL6_ONCMY (Q0GGL7), IL6_PAROL (A0S0B0), IL6_SPAAU (B6CKP4) |
UniProtKB/Swiss-Prot False positive sequences |
2 sequences
CSOCA_HALNC (O85042), SDEA_EMENI (C8V7U7) |
PDB [Detailed view] |
24 PDB
1ALU; 1BGC; 1BGD; 1BGE; 1CD9; 1GNC; 1IL6; 1P9M; 1PGR; 1RHG; 2D9Q; 2IL6; 2L3Y; 4CNI; 4J4L; 4NI7; 4NI9; 4O9H; 4ZS7; 5FUC; 5GW9; 5ZO6; 7NXZ; 8D82 » more |