PROSITE entry PS00262
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Direct ScanProsite submission
General information about the entry
Entry name [info] | INSULIN |
Accession [info] | PS00262 |
Entry type [info] | PATTERN |
Date [info] |
01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
PROSITE Doc. [info] | PDOC00235 |
Name and characterization of the entry
Description [info] | Insulin family signature. |
Pattern [info] |
C-C-{P}-{P}-x-C-[STDNEKPI]-x(3)-[LIVMFS]-x(3)-C. |
Numerical results [info]
Total number of hits | 262 in 262 different sequences |
Number of true positive hits | 254 in 254 different sequences |
Number of 'unknown' hits | 0 |
Number of false positive hits | 8 in 8 different sequences |
Number of false negative sequences | 10 |
Number of 'partial' sequences | 1 |
Precision (true positives / (true positives + false positives)) | 96.95 % |
Recall (true positives / (true positives + false negatives)) | 96.21 % |
Comments [info]
Taxonomic range [info] | Eukaryotes |
Maximum number of repetitions [info] | 1 |
Site [info] | disulfide at position 1 |
Site [info] | disulfide at position 2 |
Site [info] | disulfide at position 6 |
Site [info] | disulfide at position 11 |
Version [info] | 1 |
Cross-references [info]
UniProtKB/Swiss-Prot True positive sequences |
254 sequences
BXA1_BOMMO (Q17192), BXA1_SAMCY (P33718), BXA2_BOMMO (P15411), BXA2_SAMCY (P33719), BXA3_BOMMO (P26726), BXA3_SAMCY (P33720), BXA4_BOMMO (P26727), BXA5_BOMMO (P26728), BXA6_BOMMO (P26729), BXA7_BOMMO (P26730), BXA8_BOMMO (P26731), BXA9_BOMMO (P26732), BXB10_BOMMO (Q17194), BXB12_BOMMO (P29519), BXB1_BOMMO (P26733), BXB1_SAMCY (P33721), BXB2_BOMMO (P26734), BXB2_SAMCY (P33722), BXB3_BOMMO (P26737), BXB4_BOMMO (P26738), BXB5_BOMMO (P26739), BXB6_BOMMO (P26740), BXB7_BOMMO (P26741), BXB8_BOMMO (P26742), BXB9_BOMMO (P26743), BXC1_BOMMO (P15410), BXC2_BOMMO (P26735), BXD1_BOMMO (P26736), BXE1_BOMMO (P21808), BXF1_BOMMO (P91896), BXG1_BOMMO (O61271), BXRA_AGRCO (O09209), BXRB_AGRCO (O09210), GSS_PATPE (C9K4X8), IGF1A_CYPCA (Q90325), IGF1A_XENLA (P16501), IGF1B_CYPCA (Q90326), IGF1B_XENLA (P84775), IGF1_AILFU (Q6IVA5), IGF1_AILME (Q6JLX1), IGF1_BOVIN (P07455), IGF1_CANLF (P33712), IGF1_CAPHI (P51457), IGF1_CAVPO (P17647), IGF1_CHICK (P18254), IGF1_COTJA (P51462), IGF1_HORSE (P51458), IGF1_HUMAN (P05019), IGF1_MOUSE (P05017), IGF1_ONCKI (P17085), IGF1_ONCMY (Q02815), IGF1_PANTA (Q6GUL6), IGF1_PIG(P16545), IGF1_RABIT (Q95222), IGF1_RAT(P08025), IGF1_RHIRO (Q68LC0), IGF1_SHEEP (P10763), IGF1_SUNMU (Q28933), IGF2A_XENLA (Q90WW4), IGF2B_XENLA (Q6INW9), IGF2_BOVIN (P07456), IGF2_CAVPO (Q08279), IGF2_CHICK (P33717), IGF2_HORSE (P51459), IGF2_HUMAN (P01344), IGF2_MOUSE (P09535), IGF2_NEOVI (P41694), IGF2_ONCMY (Q02816), IGF2_PIG(P23695), IGF2_RAT(P01346), IGF2_SHEEP (P10764), IGF3_XENLA (Q90WX8), IGF_MYXGL (P22618), ILB1_CAEEL (Q09626), ILB2_CAEEL (Q09627), ILB3_CAEEL (Q09628), ILB4_CAEEL (Q23430), ILB5_CAEEL (P56174), ILB6_CAEEL (P56173), ILG1_CAEEL (Q18060), ILP_BRACL (P22334), INS17_CAEEL (G5EFH1), INS1A_CONGE (A0A0B5AC95), INS1A_CONQU (A0A0B5ABE6), INS1A_CONTU (A0A0B5ADU4), INS1B_CONGE (A0A0B5A8Q2), INS1B_CONQU (A0A0B5ABE4), INS1B_CONTU (A0A0B5AC90), INS1C_CONGE (A0A0B5A7P2), INS1_BATSP (P01337), INS1_CONFO (A0A0B5AC98), INS1_CONIM (A0A0B5A7M7), INS1_CONKI (A0A3S9V8L7), INS1_CONME (A0A0B5ADV0), INS1_CONMR (A0A0B5A8Q6), INS1_CONTE (A0A0B5A7N8), INS1_HUSDA (C0HJI7), INS1_KATPE (C0HJI2), INS1_MOUSE (P01325), INS1_RAT(P01322), INS1_THUOR (C0HJI5), INS1_XENLA (P12706), INS2A_CONFO (A0A0B5ADT9), INS2A_CONGE (A0A0B5ABD9), INS2B_CONFO (A0A0B5A7N1), INS2B_CONGE (A0A0B5ADT3), INS2C_CONFO (A0A0B5A7N5), INS2_BATSP (P01338), INS2_CONIM (A0A0B5A8P8), INS2_CONKI (A0A3S9V8K6), INS2_CONTU (A0A3S9V8L9), INS2_HUSDA (C0HJI8), INS2_KATPE (C0HJI3), INS2_MOUSE (P01326), INS2_RAT(P01323), INS2_THUOR (C0HJI6), INS2_XENLA (P12707), INS3A_CONGE (A0A0B5A8P4), INS3B_CONGE (A0A0B5AC86), INS3_CONTU (A0A0B5ABD5), INSL1_DROME (Q9VT50), INSL2_DROME (Q9VT51), INSL3_BOVIN (O77801), INSL3_CALJA (O97937), INSL3_CANLF (Q6X7V3), INSL3_DROME (Q9VT52), INSL3_HUMAN (P51460), INSL3_MOUSE (O09107), INSL3_PANTR (Q5CZK3), INSL3_PIG (P51461), INSL3_RAT (Q9WUK0), INSL4_DROME (Q9VT53), INSL4_HUMAN (Q14641), INSL4_PANTR (Q5CZK6), INSL5_DROME (Q7KUD5), INSL5_HUMAN (Q9Y5Q6), INSL5_MOUSE (Q9WUG6), INSL5_PANTR (Q5CZK5), INSL6_BOVIN (Q32L79), INSL6_HUMAN (Q9Y581), INSL6_MOUSE (Q9QY05), INSL6_RAT (Q9WV41), INS_ACIGU (P81423), INS_ACOCA (P01324), INS_ALLMI (P12703), INS_AMICA (P29335), INS_ANAPL (P01333), INS_ANGAN (P41522), INS_ANGRO (P42633), INS_ANSAN (P68245), INS_AOTTR (P67972), INS_ATRSP (P09476), INS_BALBO (P01314), INS_BALPH (P67973), INS_BOVIN (P01317), INS_CAIMO (P68243), INS_CALMI (P13190), INS_CAMDR (P01320), INS_CANLF (P01321), INS_CAPHI (P01319), INS_CARSE (C0HJI1), INS_CAVPO (P01329), INS_CHICH (P01327), INS_CHICK (P67970), INS_CHIMO (P68991), INS_CHLAE (P30407), INS_CONVC (A0A0F7YYV0), INS_CRILO (P01313), INS_CROAT (P01334), INS_CYPCA (P01335), INS_DANRE (O73727), INS_DIDVI (P18109), INS_ELEMA (P01316), INS_FELCA (P06306), INS_GADMC (P01336), INS_GORGO (Q6YK33), INS_HORSE (P01310), INS_HUMAN (P01308), INS_HYDCO (P68992), INS_HYSCR (P01328), INS_ICTTR (Q91XI3), INS_KATPE (P01340), INS_LAMFL (P68988), INS_LOPAM (P69045), INS_LOPPI (P69046), INS_MACFA (P30406), INS_MELGA (P67968), INS_MYOCO (P01330), INS_MYOSC (P07453), INS_MYXGL (P01342), INS_OCTDE (P17715), INS_ONCGO (P68989), INS_ONCKE (P04667), INS_ONCKI (P68990), INS_ORENI (P81025), INS_ORNAN (Q9TQY7), INS_PAGMA (C0HJI4), INS_PANBU (Q98TA8), INS_PANTR (P30410), INS_PETMA (P68987), INS_PHYMC (P67974), INS_PIAME (P81881), INS_PIG (P01315), INS_PLAFE (P09477), INS_PLATA (C0HJU0), INS_PONPY (Q8HXV2), INS_PROGU (P01331), INS_PSAOB (Q62587), INS_PTYDH (P12708), INS_RABIT (P01311), INS_SAISC (P67971), INS_SELRF (P51463), INS_SERQU (C0HJT9), INS_SHEEP (P01318), INS_SQUAC (P12704), INS_STRCA (P67969), INS_THUTH (P01339), INS_TORMA (P12705), INS_TRADO (P69047), INS_TRASC (P69048), INS_VERMO (Q9W7R2), IRP1_AGRIP (C0HKS3), IRP2_AGRIP (C0HKS4), IRP4_AGRIP (C0HKS5), LIRP_LOCMI (P15131), MPI1_LYMST (P07223), MPI2_LYMST (P25289), MPI3_LYMST (P80090), MPI5_LYMST (P31241), MPI7_LYMST (P91797), REL1_HUMAN (P04808), REL1_PANTR (P51454), REL1_RAT(P01347), REL2_HUMAN (P04090), REL2_PANTR (P51455), REL3_HUMAN (Q8WXF3), REL3_MOUSE (Q8CHK2), REL3_PANTR (Q5CZK2), REL3_PIG(Q8HY17), REL3_RAT(Q8BFS3), RELH_RABIT (P51456), RELX_BALAC (P11184), RELX_BALED (P11185), RELX_CANLF (Q9TRM8), RELX_CARTA (P01349), RELX_CAVPO (P51453), RELX_FELCA (Q9MYK8), RELX_HORSE (P22969), RELX_HYPSI (P81191), RELX_LEUER (P11952), RELX_MACMU (P19884), RELX_MESAU (Q64171), RELX_PIG(P01348), RELX_SQUAC (P11953)» more
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UniProtKB/Swiss-Prot False negative sequences |
10 sequences
BXB11_BOMMO (Q17196), ILA1_CAEEL (Q21507), ILA2_CAEEL (Q21508), ILA3_CAEEL (Q21506), INSL6_DROME (Q9W4Z4), INSL7_DROME (Q9W4Q9), INSL_VIGUN (P83770), INS_POLSE (P0C236), INS_RODSP (P21563), REL1_MOUSE (P47932)» more |
UniProtKB/Swiss-Prot 'Partial' sequences |
1 sequence
RELX_PHODA (Q7M3C4) |
UniProtKB/Swiss-Prot False positive sequences |
8 sequences
ADA18_MACFA (Q95194), ADAM5_RAT (Q5BK84), F256_CTEON (P85032), GG3_ARATH (Q6AWT8), O161_CONCE (Q5K0C4), O165_CONLI (Q3YEE6), PRMC_CHLT2 (B0B9D1), PRMC_CHLTR (O84027)» more |
PDB [Detailed view] |
476 PDB
1A7F; 1AI0; 1AIY; 1APH; 1B17; 1B18; 1B19; 1B2A; 1B2B; 1B2C; 1B2D; 1B2E; 1B2F; 1B2G; 1B9E; 1B9G; 1BEN; 1BOM; 1BON; 1BPH; 1BQT; 1BZV; 1CPH; 1DEI; 1DPH; 1EFE; 1EV3; 1EV6; 1EVR; 1FU2; 1FUB; 1G7A; 1G7B; 1GUJ; 1GZR; 1GZY; 1GZZ; 1H02; 1H59; 1HIQ; 1HIS; 1HIT; 1HLS; 1HTV; 1HUI; 1IGL; 1IMX; 1IOG; 1IOH; 1IZA; 1IZB; 1J73; 1JCA; 1JCO; 1K3M; 1KMF; 1LKQ; 1LPH; 1M5A; 1MHI; 1MHJ; 1MPJ; 1MSO; 1OS3; 1OS4; 1PID; 1PMX; 1Q4V; 1QIY; 1QIZ; 1QJ0; 1RWE; 1SDB; 1SF1; 1SJT; 1SJU; 1T1K; 1T1P; 1T1Q; 1TGR; 1TRZ; 1TYL; 1TYM; 1UZ9; 1W8P; 1WAV; 1WQJ; 1XDA; 1XGL; 1XW7; 1ZEG; 1ZEH; 1ZEI; 1ZNI; 1ZNJ; 2A3G; 2AIY; 2BN1; 2BN3; 2C8Q; 2C8R; 2CEU; 2DSP; 2DSQ; 2DSR; 2EFA; 2FHW; 2G4M; 2GF1; 2H67; 2H8B; 2HH4; 2HHO; 2HIU; 2INS; 2JMN; 2JUM; 2JUU; 2JUV; 2JV1; 2JZQ; 2K1V; 2K6T; 2K6U; 2K91; 2K9R; 2KBC; 2KJI; 2KJJ; 2KJU; 2KQP; 2KQQ; 2KXK; 2L1Y; 2L1Z; 2L29; 2LGB; 2LWZ; 2M1D; 2M1E; 2M2M; 2M2N; 2M2O; 2M2P; 2MLI; 2MPG; 2MPI; 2MV1; 2MVC; 2MVD; 2N2V; 2N2W; 2N2X; 2OLY; 2OLZ; 2OM0; 2OM1; 2OMG; 2OMH; 2OMI; 2QIU; 2R34; 2R35; 2R36; 2RN5; 2TCI; 2V5P; 2VJZ; 2VK0; 2W44; 2WBY; 2WC0; 2WFU; 2WFV; 2WRU; 2WRV; 2WRW; 2WRX; 2WS0; 2WS1; 2WS4; 2WS6; 2WS7; 2ZP6; 2ZPP; 3AIY; 3BXQ; 3E4Z; 3E7Y; 3E7Z; 3EXX; 3FHP; 3FQ9; 3GF1; 3GKY; 3I3Z; 3I40; 3ILG; 3INC; 3INS; 3IR0; 3JSD; 3KQ6; 3KR3; 3LRI; 3MTH; 3P2X; 3P33; 3Q6E; 3ROV; 3RTO; 3T2A; 3TT8; 3U4N; 3V19; 3V1G; 3W11; 3W12; 3W13; 3W7Y; 3W7Z; 3W80; 3ZI3; 3ZQR; 3ZS2; 3ZU1; 4A7E; 4AIY; 4AJX; 4AJZ; 4AK0; 4AKJ; 4BS3; 4CXL; 4CXN; 4CY7; 4E7T; 4E7U; 4E7V; 4EFX; 4EWW; 4EWX; 4EWZ; 4EX0; 4EX1; 4EXX; 4EY1; 4EY9; 4EYD; 4EYN; 4EYP; 4F0N; 4F0O; 4F1A; 4F1B; 4F1C; 4F1D; 4F1F; 4F1G; 4F4T; 4F4V; 4F51; 4F8F; 4FG3; 4FKA; 4GBC; 4GBI; 4GBK; 4GBL; 4GBN; 4I5Y; 4I5Z; 4IDW; 4IHN; 4INS; 4IUZ; 4IYD; 4IYF; 4M4F; 4M4H; 4M4I; 4M4J; 4M4L; 4M4M; 4NIB; 4OGA; 4P65; 4RXW; 4UNE; 4UNG; 4UNH; 4XC4; 4XSS; 5AIY; 5BOQ; 5BPO; 5BQQ; 5BTS; 5CJO; 5CNY; 5CO2; 5CO6; 5CO9; 5D52; 5D53; 5D54; 5D5E; 5E7W; 5EMS; 5EN9; 5ENA; 5FB6; 5HPR; 5HPU; 5HQI; 5HRQ; 5JYQ; 5KQV; 5L3L; 5L3M; 5L3N; 5LIS; 5MAM; 5MHD; 5MIZ; 5MT3; 5MT9; 5MWQ; 5U8Q; 5UDP; 5UOZ; 5UQA; 5URT; 5URU; 5USP; 5USS; 5USV; 5UU2; 5UU3; 5UU4; 5VIZ; 5WBT; 5WDM; 5WOB; 6B3Q; 6B70; 6BFC; 6CE7; 6CE9; 6CEB; 6CK2; 6FEY; 6FF3; 6GNQ; 6GV0; 6HN5; 6INS; 6JK8; 6JR3; 6K59; 6KH8; 6KH9; 6KHA; 6NWV; 6O17; 6OR0; 6P4Z; 6PYH; 6Q8Q; 6QQ7; 6QQG; 6QRH; 6QRK; 6RLX; 6RVA; 6S34; 6S4I; 6S4J; 6SOF; 6TC2; 6TYH; 6U46; 6UM2; 6VEP; 6VEQ; 6VER; 6VES; 6VET; 6VWG; 6VWI; 6X4X; 6Z7W; 6Z7Y; 6Z7Z; 6ZHB; 6ZI8; 7AC4; 7BW7; 7BW8; 7BWA; 7ELJ; 7INS; 7JP3; 7KD6; 7MD4; 7MD5; 7MQO; 7MQR; 7MQS; 7NHU; 7PG0; 7PG2; 7PG3; 7PG4; 7QAC; 7QGF; 7QID; 7RKD; 7RZE; 7RZF; 7RZI; 7S0Q; 7S4Y; 7SL1; 7SL2; 7SL3; 7SL4; 7SL6; 7SL7; 7STH; 7STI; 7STJ; 7STK; 7U6E; 7V3P; 7WRQ; 7YJ4; 7YQ3; 7YQ4; 7YQ5; 7YRR; 7Z5L; 7Z5Q; 8CLS; 8EYR; 8EYX; 8EYY; 8EZ0; 8GSG; 8GUY; 8HGZ; 8HSF; 8HSK; 8IPZ; 8OKY; 8ONI; 8ONK; 8ONP; 8ONR; 8PI4; 8PI5; 8PI6; 8PJC; 8PJH; 8RRP; 8RVT; 8SBD; 8TK9; 8TKT; 8TKU; 8U4C; 8U4E; 8VJB; 8VJC; 8Z4B; 9INS » more |