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PROSITE entry PS00270


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PURL: https://purl.expasy.org/prosite/signature/PS00270

Direct ScanProsite submission
General information about the entry

Entry name [info] ENDOTHELIN
Accession [info] PS00270
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-1990 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00243

Name and characterization of the entry

Description [info] Endothelin family signature.
Pattern [info] 
C-x-C-x(4)-D-x(2)-C-x(2)-[FY]-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 79 in 36 different sequences
Number of true positive hits 78 in 35 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 98.73 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 12
Site [info] disulfide at position 1
Site [info] disulfide at position 3
Site [info] disulfide at position 7
Site [info] disulfide at position 10
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 35 sequences 

EDN1_ATEAB  (Q5NRP9), EDN1_BOVIN  (P17322), EDN1_CANLF  (P13206), 

EDN1_CAVPO  (P97740), EDN1_FELCA  (Q5NRQ1), EDN1_HUMAN  (P05305), 
EDN1_MACFA  (Q28469), EDN1_MOUSE  (P22387), EDN1_PIG(P09558), 
EDN1_RABIT  (P29560), EDN1_RAT(P22388), EDN1_SHEEP  (Q9BG76), 
EDN2_ATEAB  (Q5NRP8), EDN2_BOVIN  (Q867A9), EDN2_CANLF  (P12064), 
EDN2_FELCA  (Q5NRQ0), EDN2_HORSE  (Q867D0), EDN2_HUMAN  (P20800), 
EDN2_MACFA  (Q28470), EDN2_MOUSE  (P22389), EDN2_MUSPF  (Q8MJW9), 
EDN2_RABIT  (Q765Z5), EDN2_RAT(P23943), EDN3_CANLF  (Q765Z4), 
EDN3_HUMAN  (P14138), EDN3_MOUSE  (P48299), EDN3_PIG(A5A752), 
EDN3_RABIT  (P19998), EDN3_RAT(P13207), SRTX1_ATRIR (P0DJK0), 
SRTX2_ATRIR (P0DJK1), SRTXB_ATRBI (P80163), SRTXD_ATREN (P13211), 
SRTXL_ATRMM (Q6RY98), SRTX_ATREN  (P13208)
» more

UniProtKB/Swiss-Prot
False positive sequences		 1 sequence 

THST_THETS  (Q9NBW4)


				
	

	

		PDB
[Detailed view]		
		
			21 PDB
			


			pdb_00001edn; pdb_00001edp; pdb_00001srb; pdb_00001t7h; pdb_00001v6r; pdb_00002lde; pdb_00002ldf; pdb_00005glh; pdb_00006dk5; pdb_00006igk; pdb_00006lry; pdb_00008hcq; 
			
				pdb_00008hcx; pdb_00008iy5; pdb_00008iy6; pdb_00008xgr; pdb_00008xvh; pdb_00008xvi; pdb_00008xwp; pdb_00008xwq; pdb_00008zrt
			
			

			» more