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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00278


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PURL: https://purl.expasy.org/prosite/signature/PS00278

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General information about the entry

Entry name [info] STAPH_STREP_TOXIN_2
Accession [info] PS00278
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00250

Name and characterization of the entry

Description [info] Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2.
Pattern [info] 
K-x(2)-[LIVF]-x(4)-[LIVF]-D-x(3)-R-x(2)-L-x(5)-[LIV]-Y.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 43 in 43 different sequences
Number of true positive hits 42 in 42 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 97.67 %
Recall (true positives / (true positives + false negatives)) 97.67 %

Comments [info]

Taxonomic range [info] Bacteriophages, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 42 sequences 

ENTC1_STAAU (P01553), ENTC2_STAAU (P34071), ENTC3_STAAM (P0A0L3), 

ENTC3_STAAN (P0A0L4), ENTC3_STAAU (P0A0L5), ETXA_STAAE  (A0A0H3KHN8), 
ETXA_STAAU  (P0A0L2), ETXA_STAAW  (P0A0L1), ETXB_STAAU  (P01552), 
ETXD_STAAU  (P20723), ETXE_STAAU  (P12993), ETXG_STAAM  (P0A0L6), 
ETXG_STAAN  (P0A0L7), ETXG_STAAU  (P0A0L8), ETXH_STAAU  (P0A0M0), 
ETXH_STAAW  (P0A0L9), SLL11_STAAU (A8E1U5), SPEA_BPT12  (P0DJY8), 
SPEA_STRP8  (P62561), SPEA_STRPY  (P0DJY7), SPEC_STRP1  (P0C0I5), 
SPEC_STRP6  (Q5XB82), SPEC_STRP8  (Q8NKX2), SPEG_STRP1  (Q9X5C7), 
SPEG_STRP3  (P0DG08), SPEG_STRPQ  (P0DG09), SPEH_STRP1  (P0C0I7), 
SPEH_STRPY  (P0C0I6), SSL10_STAA8 (Q2G2X7), SSL10_STAAE (A0A0H3K6Z9), 
SSL11_STAA8 (Q2G0X4), SSL11_STAAE (A0A0H3KEE7), SSL13_STAAE (A0A0H3K7M3), 
SSL3_STAA8  (Q2G0X7), SSL3_STAAE  (A0A0H3KEE1), SSL4_STAA8  (Q2G1S8), 
SSL4_STAAE  (A0A0H3K6A3), SSL5_STAA8  (Q2G1S6), SSL5_STAAE  (A0A0H3K6Z6), 
SSL7_STAA8  (Q2G2Y0), SSL7_STAAE  (A0A0H3K6Z8), TSST_STAAU  (P06886)
» more

UniProtKB/Swiss-Prot
False negative sequences		 1 sequence 

SGS1_AEDAE  (A0A1S4FPC9)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			1 sequence
			


			
ZC321_TRYB2 (Q57Y77)


				
	

	

		PDB
[Detailed view]		
		
			104 PDB
			


			pdb_00001an8; pdb_00001aw7; pdb_00001b1z; pdb_00001cqv; pdb_00001d5m; pdb_00001d5x; pdb_00001d5z; pdb_00001d6e; pdb_00001dyq; pdb_00001enf; pdb_00001esf; pdb_00001et9; 
			
				pdb_00001eu4; pdb_00001ewc; pdb_00001f77; pdb_00001goz; pdb_00001ha5; pdb_00001hqr; pdb_00001hxy; pdb_00001i4g; pdb_00001i4h; pdb_00001i4p; pdb_00001i4q; pdb_00001i4r; 
				pdb_00001i4x; pdb_00001jck; pdb_00001jwm; pdb_00001jws; pdb_00001jwu; pdb_00001klg; pdb_00001klu; pdb_00001ktk; pdb_00001l0x; pdb_00001l0y; pdb_00001lo5; pdb_00001pyw; 
				pdb_00001qil; pdb_00001sbb; pdb_00001se2; pdb_00001se3; pdb_00001se4; pdb_00001seb; pdb_00001sje; pdb_00001sjh; pdb_00001ste; pdb_00001sxt; pdb_00001t5x; pdb_00001ts2; 
				pdb_00001ts3; pdb_00001ts4; pdb_00001ts5; pdb_00001uns; pdb_00001uup; pdb_00001xxg; pdb_00002aq1; pdb_00002aq2; pdb_00002aq3; pdb_00002ij0; pdb_00002ipk; pdb_00002qil; 
				pdb_00002rdg; pdb_00002rdh; pdb_00002seb; pdb_00002tss; pdb_00002xn9; pdb_00002xna; pdb_00003bvg; pdb_00003bvm; pdb_00003bvz; pdb_00003byt; pdb_00003byy; pdb_00003bzd; 
				pdb_00003gp7; pdb_00003km9; pdb_00003r8b; pdb_00003seb; pdb_00003tss; pdb_00003ury; pdb_00003w2d; pdb_00004c56; pdb_00004dxf; pdb_00004dxg; pdb_00004ohj; pdb_00004rco; 
				pdb_00004rgm; pdb_00004rgn; pdb_00004rgo; pdb_00004tss; pdb_00004udu; pdb_00005d3d; pdb_00005d3i; pdb_00005fk9; pdb_00005fka; pdb_00005i4d; pdb_00005tss; pdb_00006lwt; 
				pdb_00006ucd; pdb_00008fjp; pdb_00008ybl; pdb_00008ybm; pdb_00008ybn; pdb_00008ybo; pdb_00008ybp; pdb_00008ykt
			
			

			» more