PROSITE entry PS00287
View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry
| Entry name [info] | CYSTATIN |
| Accession [info] | PS00287 |
| Entry type [info] | PATTERN |
| Date [info] |
01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00259 |
Name and characterization of the entry
| Description [info] | Cysteine proteases inhibitors signature. |
| Pattern [info] |
[GSTEQKRV]-Q-[LIVT]-[VAF]-[SAGQ]-G-{DG}-[LIVMNK]-{TK}-x-[LIVMFY]-{S}-
[LIVMFYA]-[DENQKRHSIV].
|
Numerical results [info]
| Total number of hits | 129 in 121 different sequences |
| Number of true positive hits | 111 in 103 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 18 in 18 different sequences |
| Number of false negative sequences | 47 |
| Number of 'partial' sequences | 5 |
| Precision (true positives / (true positives + false positives)) | 86.05 % |
| Recall (true positives / (true positives + false negatives)) | 70.25 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 3 |
| Version [info] | 2 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
103 sequences
CPI1_PIG(P35479), CPI2_BRUMA (A0A0K0IP23), CST10_MOUSE (Q9JM84), CYS17_PLARH (A0A6B9L8T7), CYS1_ORNMO (Q6QZV5), CYS2_ORNMO (Q6QD55), CYT11_ORYSJ (Q6K309), CYT12_ORYSJ (Q0JNR2), CYT1_ARATH (Q945Q1), CYT1_CROAD (J3RYX9), CYT1_HORVU (Q9LEI7), CYT1_MAIZE (P31726), CYT1_MOUSE (P35175), CYT1_ORYSJ (P09229), CYT2_ARATH (Q8L5T9), CYT2_CROAD (J3SE80), CYT2_MOUSE (P35174), CYT2_ORYSJ (P20907), CYT3_ARATH (Q41906), CYT3_MOUSE (P35173), CYT6_ARATH (Q8H0X6), CYT6_ORYSJ (Q10Q46), CYT7_ARATH (Q8LC76), CYT7_ORYSJ (Q10Q47), CYT8_ORYSJ (Q10J94), CYTA1_DICDI (Q65YR8), CYTA1_PIG (Q28988), CYTA5_PIG (Q28986), CYTA8_PIG (Q28987), CYTA_BOVIN (P80416), CYTA_FELCA (Q8WNR9), CYTA_HELAN (Q10992), CYTA_HUMAN (P01040), CYTA_MOUSE (P56567), CYTA_RAT(P01039), CYTA_SARPE (P31727), CYTB_BOVIN (P25417), CYTB_GORGO (Q76LA0), CYTB_HELAN (Q10993), CYTB_HUMAN (P04080), CYTB_MACFU (Q862Z5), CYTB_MOUSE (Q62426), CYTB_OPLFA (J7FQE8), CYTB_PANPA (P60575), CYTB_PANTR (Q8I030), CYTB_PIG(Q29290), CYTB_PONPY (P60576), CYTB_RAT(P01041), CYTB_SHEEP (Q10994), CYTC_BOVIN (P01035), CYTC_HUMAN (P01034), CYTC_MACMU (O19092), CYTC_MOUSE (P21460), CYTC_PAROL (B2Z450), CYTC_RAT(P14841), CYTC_SAISC (O19093), CYTD_HUMAN (P28325), CYTI_VIGUN (Q06445), CYTL2_IXOSC (B7PKZ1), CYTLG_IXOSC (B7PKZ2), CYTL_DROME (P23779), CYTL_IXOSC (Q8MVB6), CYTL_TACTR (Q7M429), CYTM_HUMAN (Q15828), CYTM_SOLTU (P37842), CYTN_HUMAN (P01037), CYTS_HUMAN (P01036), CYTS_RAT(P19313), CYTT_HUMAN (P09228), CYTX_BOVIN (P35478), CYTX_ONCVO (P22085), CYT_BITAR (P08935), CYT_BITGA (Q6T6T4), CYT_CHICK (P01038), CYT_CHIGU (B1P1J3), CYT_COTJA (P81061), CYT_CRYNI (E3P6P1), CYT_CYPCA (P35481), CYT_MICIK (E3P6P3), CYT_NAJKA (E3P6P4), CYT_NOTSC (E3P6P2), CYT_ONCKE (Q98967), CYT_ONCMY (Q91195), CYT_OXYMI (E3P6N5), CYT_OXYSC (E3P6N6), CYT_PSEAU (E3P6N8), CYT_PSEPO (E3P6N7), CYT_PSETE (E3P6N4), CYT_SOLTU (Q03196), EPI2B_PHYIN (A1L017), EPI2B_PHYIT (D0NBV3), EPIC1_PHYIN (A1L015), EPIC1_PHYIT (D0NBV1), EPIC4_PHYIN (A1L019), EPIC4_PHYIT (D0MSS2), KNG1_BOVIN (P01044), KNG1_HUMAN (P01042), KNG1_MOUSE (O08677), KNG1_RAT(P08934), KNG2_BOVIN (P01045), KNT1_RAT(P01048), KNT2_RAT(P08932), T71A_HADIN (P0DXA0)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
47 sequences
22P1_RAT(P22282), 22P2_RAT(P22283), CPI1_BRUMA (P90698), CPI1_CAEEL (G5EDZ9), CPI2_CAEEL (G5ECM9), CST11_HUMAN (Q9H112), CST11_MOUSE (Q9D269), CST11_RAT (Q8K5A3), CST12_MOUSE (Q9DAN8), CST12_RAT (Q8VII2), CST13_MOUSE (Q80ZN5), CST14_MOUSE (Q8VII3), CST14_RAT (Q8VIH8), CST15_BOVIN (Q2NKZ5), CST16_BOVIN (Q32KQ9), CST8_HUMAN (O60676), CST8_MOUSE (P32766), CST8_RAT(O88969), CST9L_HUMAN (Q9H4G1), CST9P_HUMAN (Q5W188), CST9_BOVIN (Q29RH0), CST9_HUMAN (Q5W186), CST9_MOUSE (Q9Z0H6), CSTL1_HUMAN (Q9H114), CSTL1_MOUSE (Q80Y72), CYT10_ORYSI (A2XS65), CYT10_ORYSJ (P0C579), CYT1_ACTCC (P86472), CYT1_ACTDE (Q6TPK4), CYT3_ORYSJ (Q6I570), CYT4_ARATH (Q84WT8), CYT4_ORYSJ (Q5N806), CYT5_ARATH (Q41916), CYT5_ORYSJ (Q0JGM8), CYT9_ORYSJ (Q10Q48), CYTA2_DICDI (Q65YR7), CYTA3_DICDI (Q5R1U3), CYTB_PAROL (B2Z449), CYTC_RABIT (O97862), CYTF_HUMAN (O76096), CYTF_MOUSE (O89098), CYT_AUSSU (E3P6N3), CYT_NAJAT (P81714), HRG_HUMAN (P04196), HRG_MOUSE (Q9ESB3), HRG_RABIT (Q28640), HRG_RAT (Q99PS8)» more |
| UniProtKB/Swiss-Prot 'Partial' sequences |
5 sequences
CPI2_PIG(P80736), CYT1_CAPHI (P84911), CYT2_CAPHI (P84910), CYT3_WISFL (P19864), CYT_SOYBN (P25973)» more |
| UniProtKB/Swiss-Prot False positive sequences |
18 sequences
ABCB4_DICDI (Q54W24), ACT_BACMT (Q8KP10), ADPP_BACSU (P54570), ATPE_ALCBS (Q0VKX5), HEM1_CAMC5 (A7GYU7), KGUA_BACFN (Q5L9N9), KGUA_BACFR (Q64PY1), MRAY_ENTFA (O07107), OADC_PSEMY (A4XQ41), PP4R2_MOUSE (Q0VGB7), SASA_PROMP (Q7V113), SIP5_COCIM (Q1DZ34), SPXH_OCEIH (Q8ERT3), SYM_METM5 (A4FZL1), SYM_METM7 (A6VIW5), SYM_METMP (Q6M0E5), TICRR_DANRE (Q6DRL4), TOP1_MYCS2 (A0R5D9)» more |
| PDB [Detailed view] |
41 PDB
1A67; 1A90; 1CEW; 1CYU; 1CYV; 1DVC; 1DVD; 1EQK; 1G96; 1GD3; 1GD4; 1N9J; 1NB3; 1NB5; 1R4C; 1RN7; 1ROA; 1STF; 1TIJ; 1YVB; 2OCT; 3GAX; 3K9M; 3KFQ; 3KSE; 3L0R; 3LH4; 3MWZ; 3PS8; 3QRD; 4LZI; 4N6L; 4N6M; 4N6N; 4N6O; 4N6V; 4TX4; 4ZM8; 6FK0; 8GT0; 8GT7 » more |