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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00292


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PURL: https://purl.expasy.org/prosite/signature/PS00292

Direct ScanProsite submission
General information about the entry

Entry name [info] CYCLINS
Accession [info] PS00292
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00264

Name and characterization of the entry

Description [info] Cyclins signature.
Pattern [info] 
R-x(2)-[LIVMSA]-x(2)-[FYWS]-[LIVM]-x(8)-[LIVMFC]-x(4)-[LIVMFYA]-x(2)-
[STAGC]-[LIVMFYQ]-x-[LIVMFYC]-[LIVMFY]-D-[RKH]-[LIVMFYW].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 179 in 179 different sequences
Number of true positive hits 179 in 179 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 161
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 52.65 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 179 sequences 

CCA11_ARATH (Q9C6Y3), CCA11_ORYSJ (Q7F830), CCA12_ARATH (Q9FVX0), 

CCA12_ORYSJ (Q0JPA4), CCA13_ORYSJ (Q0INT0), CCA14_ORYSJ (Q0DJR9), 
CCA21_ARATH (Q39071), CCA21_ORYSJ (Q2QQ96), CCA22_ARATH (Q147G5), 
CCA31_ARATH (Q9FMH5), CCA31_ORYSJ (Q75I54), CCA32_ORYSJ (Q2QN26), 
CCA33_ARATH (A0MEB5), CCA34_ARATH (Q3ECW2), CCB11_ARATH (P30183), 
CCB11_ORYSJ (Q0JIF2), CCB12_ARATH (Q39067), CCB13_ARATH (Q39069), 
CCB14_ARATH (O48790), CCB15_ARATH (Q39072), CCB15_ORYSJ (Q0DH40), 
CCB21_ARATH (Q39068), CCB21_ORYSI (Q01J96), CCB21_ORYSJ (Q7XSJ6), 
CCB22_ARATH (Q39070), CCB22_ORYSI (A2YH60), CCB22_ORYSJ (Q0D9C7), 
CCB23_ARATH (Q9LDM4), CCB24_ARATH (Q9SFW6), CCB31_ARATH (Q9SA32), 
CCD11_ARATH (P42751), CCD12_ORYSJ (Q8H339), CCD21_ARATH (P42752), 
CCD21_ORYSJ (Q0J233), CCD22_ORYSJ (Q8LHA8), CCD23_ORYSJ (Q10K98), 
CCD31_ARATH (P42753), CCD31_ORYSJ (Q69QB8), CCD32_ARATH (Q9FGQ7), 
CCD33_ARATH (Q9SN11), CCD41_ARATH (Q8LGA1), CCD41_ORYSJ (Q6YXH8), 
CCD42_ARATH (Q0WQN9), CCD42_ORYSJ (Q4KYM5), CCD52_ORYSJ (Q2QMW1), 
CCF21_ORYSJ (Q6K1Z6), CCF22_ORYSJ (Q6K8S0), CCF31_ORYSJ (Q10Q63), 
CCF32_ORYSJ (Q10Q62), CCN1_ANTMA  (P34800), CCN2_ANTMA  (P34801), 
CCNA1_CARAU (Q92161), CCNA1_HUMAN (P78396), CCNA1_MOUSE (Q61456), 
CCNA1_RAT   (Q6AY13), CCNA1_XENLA (P18606), CCNA2_BOVIN (P30274), 
CCNA2_CHICK (P43449), CCNA2_HUMAN (P20248), CCNA2_MESAU (P37881), 
CCNA2_MOUSE (P51943), CCNA2_XENLA (P47827), CCNAL_DAUCA (P25010), 
CCNA_DROME  (P14785), CCNA_HYDVD  (P51986), CCNA_PATVU  (P24861), 
CCNA_SPISO  (P04962), CCNB1_ANGJA (Q60FY0), CCNB1_BOVIN (Q1LZG6), 
CCNB1_CAEEL (Q10653), CCNB1_CARAU (Q92162), CCNB1_CRIGR (Q08301), 
CCNB1_HUMAN (P14635), CCNB1_MEDSV (P46277), CCNB1_MESAU (P37882), 
CCNB1_MOUSE (P24860), CCNB1_ORYCU (Q9DGA4), CCNB1_ORYJA (Q9DGA0), 
CCNB1_ORYLA (Q9IBG1), CCNB1_ORYLU (Q9DG97), CCNB1_RAT   (P30277), 
CCNB1_SOYBN (P25011), CCNB1_XENLA (P13350), CCNB2_ANGJA (Q60FX9), 
CCNB2_BOVIN (O77689), CCNB2_CHICK (P29332), CCNB2_HUMAN (O95067), 
CCNB2_MACFA (Q4R7A8), CCNB2_MEDSA (P30278), CCNB2_MEDSV (P46278), 
CCNB2_MESAU (P37883), CCNB2_MOUSE (P30276), CCNB2_ORYJA (Q9DG99), 
CCNB2_ORYLA (Q9IBG0), CCNB2_ORYLU (Q9DG96), CCNB2_RANJA (O93229), 
CCNB2_SOYBN (P25012), CCNB2_XENLA (P13351), CCNB3_CANLF (Q659K0), 
CCNB3_CHICK (P39963), CCNB_ARBPU  (P07818), CCNB_DICDI  (P42524), 
CCNB_DROME  (P20439), CCNB_HYDVD  (P51987), CCNB_HYDVU  (P51988), 
CCNB_MARGL  (P15206), CCNB_PATPE  (P18063), CCNB_PATVU  (P24862), 
CCNB_SPISO  (P13952), CCND1_BOVIN (Q2KI22), CCND1_CHICK (P55169), 
CCND1_DANRE (Q90459), CCND1_HUMAN (P24385), CCND1_MOUSE (P25322), 
CCND1_PONAB (Q5R6J5), CCND1_RAT   (P39948), CCND1_XENLA (P50755), 
CCND2_BOVIN (Q0P5D3), CCND2_CHICK (P49706), CCND2_HUMAN (P30279), 
CCND2_MOUSE (P30280), CCND2_PIG   (Q8WNW2), CCND2_RAT   (Q04827), 
CCND2_XENLA (P53782), CCND3_BOVIN (Q3MHH5), CCND3_HUMAN (P30281), 
CCND3_MOUSE (P30282), CCND3_RAT   (P48961), CCND_CAEEL  (Q9U2M5), 
CCNE1_CHICK (P49707), CCNE1_DANRE (P47794), CCNE1_HUMAN (P24864), 
CCNE1_MOUSE (Q61457), CCNE1_RAT   (P39949), CCNE1_XENLA (P50756), 
CCNE2_BOVIN (Q5E9K7), CCNE2_HUMAN (O96020), CCNE2_MOUSE (Q9Z238), 
CCNE2_XENLA (Q91780), CCNE3_XENLA (O42575), CCNE_CAEEL  (O01501), 
CCNE_DROME  (P54733), CCNF_BOVIN  (A5PK16), CCNF_DANRE  (Q6NYX6), 
CCNF_HUMAN  (P41002), CCNF_MOUSE  (P51944), CCNF_RAT(Q8K4F8), 
CCNF_XENLA  (Q7T0L6), CCNF_XENTR  (Q5XGG5), CCNOA_XENLA (Q32NJ2), 
CCNOB_XENLA (Q32NM1), CCSDS_ARATH (Q1PFW3), CCSDS_ORYSJ (Q10PQ9), 
CG11_CANAL  (Q59YH3), CG11_CANAW  (C4YR54), CG11_CANAX  (P0CY18), 
CG11_YEAST  (P20437), CG12_CANAX  (P43062), CG12_YEAST  (P20438), 
CG13_CANAL  (Q5A1N6), CG13_YEAST  (P13365), CG1_COLGL   (Q06374), 
CG21_CANAL  (Q5ALY0), CG21_CANAX  (P47829), CG21_EMENI  (P30284), 
CG21_SCHPO  (P24865), CG21_YEAST  (P24868), CG22_SCHPO  (P36630), 
CG22_YEAST  (P24869), CG23_SCHPO  (P10815), CG23_YEAST  (P24870), 
CG24_CANAL  (Q5A0A9), CG24_YEAST  (P24871), CGH2_SHV21  (Q01043), 
CGS5_YEAST  (P30283), CGS6_YEAST  (P32943), HGC1_CANAL  (Q5ABE2), 
REM1_SCHPO  (O14332), VCYCL_HHV8P (Q77Q36)
» more

UniProtKB/Swiss-Prot
False negative sequences		 161 sequences 

CCA23_ARATH (Q38819), CCA24_ARATH (Q9C968), CCA32_ARATH (Q9C6A9), 

CCB12_ORYSJ (Q0DWQ7), CCB13_ORYSJ (Q0JNK6), CCB25_ARATH (Q9LM91), 
CCC11_ARATH (Q9FJK6), CCC11_ORYSJ (P93411), CCC12_ARATH (Q9FJK7), 
CCD11_ORYSJ (Q67V81), CCD32_ORYSJ (Q0J3H7), CCD51_ARATH (Q2V3B2), 
CCD51_ORYSJ (Q0DQA9), CCD53_ORYSJ (Q10QA2), CCD61_ARATH (Q9ZR04), 
CCD61_ORYSJ (Q69S43), CCD71_ARATH (Q9LZM0), CCD71_ORYSJ (Q53MB7), 
CCF11_ORYSJ (Q6K1Z1), CCF12_ORYSJ (Q6K8S5), CCF13_ORYSJ (Q6K8S1), 
CCF14_ORYSJ (Q6K8S3), CCH11_ARATH (Q8W5S1), CCH11_ORYSJ (Q10D80), 
CCJ18_ARATH (Q9C5X2), CCL11_ARATH (Q8RWV3), CCL11_ORYSJ (Q9AS36), 
CCL1_YEAST  (P37366), CCN1_TRYBB  (P41179), CCNA1_CAEEL (P34638), 
CCNB3_CAEEL (Q10654), CCNB3_DROME (Q9I7I0), CCNB3_HUMAN (Q8WWL7), 
CCNB3_MOUSE (Q810T2), CCNC_AEDAE  (Q16JA2), CCNC_ANOGA  (Q7QB13), 
CCNC_BOVIN  (Q3ZCK5), CCNC_CAEBR  (P0C654), CCNC_CAEEL  (Q9TYP2), 
CCNC_CHICK  (P55168), CCNC_DICDI  (Q86KE7), CCNC_DROME  (P25008), 
CCNC_DROPS  (Q29AI1), CCNC_HUMAN  (P24863), CCNC_MOUSE  (Q62447), 
CCNC_RAT(P39947), CCNC_XENLA  (Q4KLA0), CCNC_XENTR  (Q28F72), 
CCND_OSTTA  (Q5SCB5), CCNE_HEMPU  (O15995), CCNG1_BOVIN (Q5E9I1), 
CCNG1_HUMAN (P51959), CCNG1_MOUSE (P51945), CCNG1_PIG   (Q52QT8), 
CCNG1_PONAB (Q5R5D0), CCNG1_RAT   (P39950), CCNH_BOVIN  (Q3ZBL9), 
CCNH_ECHMU  (Q9GP34), CCNH_HUMAN  (P51946), CCNH_MACFA  (Q4R7U4), 
CCNH_MOUSE  (Q61458), CCNH_RAT(Q9R1A0), CCNH_XENLA  (P51947), 
CCNI2_HUMAN (Q6ZMN8), CCNI_HUMAN  (Q14094), CCNI_MOUSE  (Q9Z2V9), 
CCNJL_HUMAN (Q8IV13), CCNJL_MOUSE (Q5SRT8), CCNJ_HUMAN  (Q5T5M9), 
CCNJ_MOUSE  (Q3TZI6), CCNJ_XENLA  (Q6DFJ9), CCNK_HUMAN  (O75909), 
CCNK_MOUSE  (O88874), CCNL1_CHICK (Q5ZJP9), CCNL1_DANRE (Q7ZVX0), 
CCNL1_HUMAN (Q9UK58), CCNL1_MOUSE (Q52KE7), CCNL1_PONAB (Q5RD50), 
CCNL1_RAT   (Q9R1Q2), CCNL1_XENLA (Q6GN15), CCNL2_HUMAN (Q96S94), 
CCNL2_MOUSE (Q9JJA7), CCNL2_RAT   (Q5I0H5), CCNL2_XENTR (Q5BKF8), 
CCNO_HUMAN  (P22674), CCNO_MOUSE  (P0C242), CCNQ_DANRE  (Q503D6), 
CCNQ_HUMAN  (Q8N1B3), CCNQ_MOUSE  (Q8QZR8), CCNQ_RAT(Q4QQW5), 
CCNQ_XENLA  (Q6NRK9), CCNT1_HORSE (Q9XT26), CCNT1_HUMAN (O60563), 
CCNT1_MOUSE (Q9QWV9), CCNT1_PANTR (Q8HXN7), CCNT2_HUMAN (O60583), 
CCNY_CAEEL  (P34624), CCNY_HUMAN  (Q8ND76), CCNY_MOUSE  (Q8BGU5), 
CCP11_ORYSJ (Q0J9W0), CCP21_ORYSJ (Q7FAT5), CCP31_ORYSJ (Q75HV0), 
CCP41_ORYSJ (Q7XC35), CCT11_ARATH (Q9C8P7), CCT11_ORYSJ (Q0E474), 
CCT12_ARATH (Q56YF8), CCT12_ORYSJ (Q6Z7H3), CCT13_ARATH (Q8LBC0), 
CCT13_ORYSJ (Q2RAC5), CCT14_ARATH (Q8GYM6), CCT14_ORYSJ (Q2QQS5), 
CCT15_ARATH (Q9FKE6), CCU11_ARATH (Q9LJ45), CCU21_ARATH (Q9SHD3), 
CCU22_ARATH (Q9M205), CCU31_ARATH (Q8LB60), CCU41_ARATH (O80513), 
CCU42_ARATH (Q9LY16), CCU43_ARATH (Q9FKF6), CCY1A_XENLA (Q5U5D0), 
CCY1B_XENLA (Q6NRF4), CCYL1_DANRE (Q08CI4), CCYL1_HUMAN (Q8N7R7), 
CCYL1_MOUSE (D3YUJ3), CCYL1_XENTR (Q28EL0), CGM2_SCHPO  (P36613), 
CGP1_SCHPO  (P87049), CLG1_YEAST  (P35190), CTK2_YEAST  (P46962), 
PCL10_YEAST (P53124), PCL1_YEAST  (P24867), PCL2_YEAST  (P25693), 
PCL5_YEAST  (P38794), PCL6_YEAST  (P40038), PCL7_YEAST  (P40186), 
PCL8_YEAST  (Q08966), PCL9_YEAST  (Q12477), PHO80_YEAST (P20052), 
PREG_NEUCR  (Q06712), PSL1_SCHPO  (O42979), PUC1_SCHPO  (P25009), 
SRB11_SCHPO (O94503), SSN8_ASPCL  (A1C7R6), SSN8_ASPFU  (Q4WZT9), 
SSN8_ASPOR  (Q2UDB2), SSN8_ASPTN  (Q0CV29), SSN8_CANAL  (Q5A4H9), 
SSN8_CANGA  (Q6FJE8), SSN8_CHAGB  (Q2GVK1), SSN8_COCIM  (Q1EAW8), 
SSN8_DEBHA  (Q6BYF8), SSN8_EMENI  (Q5BBA8), SSN8_EREGS  (Q75AX7), 
SSN8_GIBMO  (Q9C1M4), SSN8_KLULA  (Q6CP20), SSN8_MYCMD  (Q4P101), 
SSN8_NEUCR  (Q9HE63), SSN8_PICST  (A3LPX1), SSN8_PYRO7  (A4RD79), 
SSN8_YARLI  (Q6CAC7), SSN8_YEAST  (P47821)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

CCNB1_MEDSA (P30286)


				
	

	

		PDB
[Detailed view]		
		
			163 PDB
			


			pdb_00001bu2; pdb_00001e9h; pdb_00001fin; pdb_00001fvv; pdb_00001gy3; pdb_00001h1p; pdb_00001h1q; pdb_00001h1r; pdb_00001h1s; pdb_00001h24; pdb_00001h25; pdb_00001h26; 
			
				pdb_00001h27; pdb_00001h28; pdb_00001jow; pdb_00001jst; pdb_00001jsu; pdb_00001ogu; pdb_00001oi9; pdb_00001oiu; pdb_00001oiy; pdb_00001okv; pdb_00001okw; pdb_00001ol1; 
				pdb_00001ol2; pdb_00001p5e; pdb_00001pkd; pdb_00001qmz; pdb_00001urc; pdb_00001vin; pdb_00001vyw; pdb_00001w98; pdb_00001xo2; pdb_00002b9r; pdb_00002bkz; pdb_00002bpm; 
				pdb_00002c4g; pdb_00002c5n; pdb_00002c5o; pdb_00002c5v; pdb_00002c5x; pdb_00002c6t; pdb_00002cch; pdb_00002cci; pdb_00002cjm; pdb_00002euf; pdb_00002f2c; pdb_00002g9x; 
				pdb_00002i40; pdb_00002iw6; pdb_00002iw8; pdb_00002iw9; pdb_00002jgz; pdb_00002uue; pdb_00002uzb; pdb_00002uzd; pdb_00002uze; pdb_00002uzl; pdb_00002v22; pdb_00002w96; 
				pdb_00002w99; pdb_00002w9f; pdb_00002w9z; pdb_00002wev; pdb_00002wfy; pdb_00002whb; pdb_00002wih; pdb_00002wip; pdb_00002wma; pdb_00002wmb; pdb_00002wpa; pdb_00002wxv; 
				pdb_00002x1n; pdb_00003bht; pdb_00003bhu; pdb_00003bhv; pdb_00003ddp; pdb_00003ddq; pdb_00003dog; pdb_00003eid; pdb_00003ej1; pdb_00003eoc; pdb_00003f5x; pdb_00003g33; 
				pdb_00003my5; pdb_00003qhr; pdb_00003qhw; pdb_00003tnw; pdb_00004bck; pdb_00004bcm; pdb_00004bcn; pdb_00004bco; pdb_00004bcp; pdb_00004bcq; pdb_00004cfm; pdb_00004cfn; 
				pdb_00004cfu; pdb_00004cfv; pdb_00004cfw; pdb_00004cfx; pdb_00004eoi; pdb_00004eoj; pdb_00004eok; pdb_00004eol; pdb_00004eom; pdb_00004eon; pdb_00004eoo; pdb_00004eop; 
				pdb_00004eoq; pdb_00004eor; pdb_00004eos; pdb_00004fx3; pdb_00004i3z; pdb_00004ii5; pdb_00004tth; pdb_00004y72; pdb_00004yc3; pdb_00005cyi; pdb_00005hq0; pdb_00005if1; 
				pdb_00005l2w; pdb_00005lmk; pdb_00005lqf; pdb_00005nev; pdb_00006ath; pdb_00006gu2; pdb_00006gu3; pdb_00006gu4; pdb_00006gub; pdb_00006guc; pdb_00006gue; pdb_00006guf; 
				pdb_00006gva; pdb_00006p3w; pdb_00006p8e; pdb_00006p8f; pdb_00006p8g; pdb_00006p8h; pdb_00006q6g; pdb_00006q6h; pdb_00006rij; pdb_00006sg4; pdb_00007ack; pdb_00007b5l; 
				pdb_00007b5r; pdb_00007b7s; pdb_00007kjs; pdb_00007luo; pdb_00007mkx; pdb_00007nj0; pdb_00007qhl; pdb_00007sj3; pdb_00007xqk; pdb_00008b54; pdb_00008bya; pdb_00008bzo; 
				pdb_00008h4r; pdb_00008h6p; pdb_00008h6t; pdb_00008roz; pdb_00008vq3; pdb_00008vq4; pdb_00009cb3
			
			

			» more