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PROSITE entry PS00303


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PURL: https://purl.expasy.org/prosite/signature/PS00303

Direct ScanProsite submission
General information about the entry

Entry name [info] S100_CABP
Accession [info] PS00303
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00275

Name and characterization of the entry

Description [info] S-100/ICaBP type calcium binding protein signature.
Pattern [info] 
[LIVMFYW](2)-x(2)-[LKQ]-D-x(3)-[DN]-x(3)-[DNSG]-[FY]-x-[ES]-[FYVC]-x(2)-
[LIVMFS]-[LIVMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 93 in 93 different sequences
Number of true positive hits 86 in 86 different sequences
Number of 'unknown' hits 0
Number of false positive hits 7 in 7 different sequences
Number of false negative sequences 14
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 92.47 %
Recall (true positives / (true positives + false negatives)) 86.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 86 sequences 

CML45_ARATH (Q9MBG5), FILA2_HUMAN (Q5D862), FILA2_MOUSE (Q2VIS4), 

FILA_HUMAN  (P20930), HORN_HUMAN  (Q86YZ3), HORN_MOUSE  (Q8VHD8), 
M126_CHICK  (P28318), RPTN_HUMAN  (Q6XPR3), RPTN_MOUSE  (P97347), 
S100B_BOVIN (P02638), S100B_HUMAN (P04271), S100B_MOUSE (P50114), 
S100B_RABIT (Q6YNR6), S100B_RAT   (P04631), S100G_BOVIN (P02633), 
S100G_HORSE (Q865V3), S100G_HUMAN (P29377), S100G_MOUSE (P97816), 
S100G_PIG   (P02632), S100G_RAT   (P02634), S100P_HUMAN (P25815), 
S100Z_DANRE (Q503K9), S100Z_HUMAN (Q8WXG8), S10A1_BOVIN (P02639), 
S10A1_HUMAN (P23297), S10A1_MISFO (Q7LZT1), S10A1_MOUSE (P56565), 
S10A1_PONAB (Q5RC36), S10A1_RAT   (P35467), S10A2_BOVIN (P10462), 
S10A2_HUMAN (P29034), S10A3_HUMAN (P33764), S10A3_MOUSE (P62818), 
S10A3_RAT   (P62819), S10A4_BOVIN (P35466), S10A4_CANLF (Q9TV56), 
S10A4_HUMAN (P26447), S10A4_MOUSE (P07091), S10A4_RAT   (P05942), 
S10A5_HUMAN (P33763), S10A5_MOUSE (P63084), S10A5_RAT   (P63083), 
S10A6_CHICK (Q98953), S10A6_HORSE (O77691), S10A6_HUMAN (P06703), 
S10A6_MOUSE (P14069), S10A6_PIG   (Q2EN75), S10A6_RABIT (P30801), 
S10A6_RAT   (P05964), S10A7_BOVIN (Q28050), S10A7_HORSE (Q14ST5), 
S10A7_HUMAN (P31151), S10A8_BOVIN (P28782), S10A8_HUMAN (P05109), 
S10A8_MOUSE (P27005), S10A8_RAT   (P50115), S10A9_BOVIN (P28783), 
S10A9_HUMAN (P06702), S10A9_MOUSE (P31725), S10A9_RABIT (P50117), 
S10A9_RAT   (P50116), S10AA_BOVIN (P60902), S10AA_CHICK (P27003), 
S10AA_HUMAN (P60903), S10AA_MACMU (P62504), S10AA_MOUSE (P08207), 
S10AA_PIG   (P04163), S10AA_RABIT (Q6SQH4), S10AA_RAT   (P05943), 
S10AB_CHICK (P24479), S10AB_HUMAN (P31949), S10AB_MOUSE (P50543), 
S10AB_PIG   (P31950), S10AB_RABIT (P24480), S10AB_RAT   (Q6B345), 
S10AC_BOVIN (P79105), S10AC_HUMAN (P80511), S10AC_PIG   (P80310), 
S10AC_RABIT (O77791), S10AG_BOVIN (Q0VCM0), S10AG_HUMAN (Q96FQ6), 
S10I_ICTPU  (Q91061), S1A7A_HUMAN (Q86SG5), TRHY_HUMAN  (Q07283), 
TRHY_RABIT  (P37709), TRHY_SHEEP  (P22793)
» more

UniProtKB/Swiss-Prot
False negative sequences		 14 sequences 

S10AA_XENLA (P27004), S10AD_BOVIN (P79342), S10AD_HUMAN (Q99584), 

S10AD_MOUSE (P97352), S10AE_BOVIN (Q3MHP3), S10AE_HUMAN (Q9HCY8), 
S10AE_MOUSE (Q9D2Q8), S115A_GORGO (A7K6Y8), S115A_MOUSE (Q6S5I3), 
S115A_PONAB (A7K6Y9), S1A7B_HUMAN (Q5SY68), TCHL1_BOVIN (A6QP92), 
TCHL1_HUMAN (Q5QJ38), TCHL1_MOUSE (Q9D3P1)
» more

UniProtKB/Swiss-Prot
False positive sequences		 7 sequences 

CABP7_HUMAN (Q86V35), CABP7_MOUSE (Q91ZM8), CABP7_PAPAN (Q866X0), 

CABP7_RAT   (Q66H96), CABP8_HUMAN (Q9BXU9), CABP8_MOUSE (Q9JJG7), 
CABP8_RAT   (Q06BI3)
» more

PDB
[Detailed view]		 177 PDB

pdb_00001a03; pdb_00001a4p; pdb_00001b1g; pdb_00001b4c; pdb_00001boc; pdb_00001bod; pdb_00001bt6; pdb_00001cb1; pdb_00001cdn; pdb_00001cfp; pdb_00001clb; pdb_00001cnp; pdb_00001d1o; pdb_00001dt7; pdb_00001e8a; pdb_00001gqm; pdb_00001ht9; pdb_00001ig5; pdb_00001igv; pdb_00001irj; pdb_00001j55; pdb_00001jwd; pdb_00001k2h; pdb_00001k8u; pdb_00001k96; pdb_00001k9k; pdb_00001k9p; pdb_00001kcy; pdb_00001kqv; pdb_00001ksm; pdb_00001kso; pdb_00001m31; pdb_00001mho; pdb_00001mq1; pdb_00001mr8; pdb_00001mwn; pdb_00001n65; pdb_00001nsh; pdb_00001odb; pdb_00001ozo; pdb_00001psb; pdb_00001psr; pdb_00001qlk; pdb_00001qls; pdb_00001sym; pdb_00001uwo; pdb_00001xk4; pdb_00001xyd; pdb_00001zfs; pdb_00002bca; pdb_00002bcb; pdb_00002cnp; pdb_00002h61; pdb_00002jpt; pdb_00002jtt; pdb_00002k2f; pdb_00002k7o; pdb_00002kax; pdb_00002kay; pdb_00002kbm; pdb_00002l0p; pdb_00002l50; pdb_00002l51; pdb_00002lhl; pdb_00002lls; pdb_00002llt; pdb_00002llu; pdb_00002lnk; pdb_00002lp2; pdb_00002lp3; pdb_00002luc; pdb_00002lux; pdb_00002m1k; pdb_00002m3w; pdb_00002m49; pdb_00002m9g; pdb_00002maz; pdb_00002mjw; pdb_00002mrd; pdb_00002pru; pdb_00002psr; pdb_00002q91; pdb_00002rgi; pdb_00002wc8; pdb_00002wcb; pdb_00002wce; pdb_00002wcf; pdb_00002wnd; pdb_00002wor; pdb_00002wos; pdb_00002y5i; pdb_00003c1v; pdb_00003cga; pdb_00003cr2; pdb_00003cr4; pdb_00003cr5; pdb_00003czt; pdb_00003d0y; pdb_00003d10; pdb_00003gk1; pdb_00003gk2; pdb_00003gk4; pdb_00003hcm; pdb_00003icb; pdb_00003iqo; pdb_00003iqq; pdb_00003ko0; pdb_00003lk0; pdb_00003lk1; pdb_00003lle; pdb_00003m0w; pdb_00003nsi; pdb_00003nsk; pdb_00003nsl; pdb_00003nso; pdb_00003nxa; pdb_00003psr; pdb_00003rlz; pdb_00003rm1; pdb_00003zwh; pdb_00004aqi; pdb_00004aqj; pdb_00004cfq; pdb_00004cfr; pdb_00004dir; pdb_00004drw; pdb_00004duq; pdb_00004eto; pdb_00004fqo; pdb_00004ftg; pdb_00004ggf; pdb_00004hre; pdb_00004hrg; pdb_00004hrh; pdb_00004hsz; pdb_00004icb; pdb_00004p2y; pdb_00004pcw; pdb_00004pdz; pdb_00004pe0; pdb_00004pe1; pdb_00004pe4; pdb_00004pe7; pdb_00004xjk; pdb_00004xyn; pdb_00004ybh; pdb_00005csf; pdb_00005csi; pdb_00005csj; pdb_00005csn; pdb_00005d7f; pdb_00005dkn; pdb_00005dkq; pdb_00005dkr; pdb_00005er4; pdb_00005er5; pdb_00005hlo; pdb_00005hlv; pdb_00005hyd; pdb_00005i8n; pdb_00005k89; pdb_00005lpu; pdb_00005w1f; pdb_00006ds2; pdb_00006t58; pdb_00006wn7; pdb_00006zdy; pdb_00007nmi; pdb_00007psp; pdb_00007psq; pdb_00007quv; pdb_00007ui5; pdb_00008fj8; pdb_00008sjb; pdb_00008sjc; pdb_00008vk3; pdb_00008vk4
» more