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PROSITE entry PS00303


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General information about the entry

Entry name [info] S100_CABP
Accession [info] PS00303
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
03-MAY-2023 INFO UPDATE.
PROSITE Doc. [info] PDOC00275

Name and characterization of the entry

Description [info] S-100/ICaBP type calcium binding protein signature.
Pattern [info] 
[LIVMFYW](2)-x(2)-[LKQ]-D-x(3)-[DN]-x(3)-[DNSG]-[FY]-x-[ES]-[FYVC]-x(2)-
[LIVMFS]-[LIVMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2023_02 which contains 569'516 sequence entries.


Total number of hits 92 in 92 different sequences
Number of true positive hits 85 in 85 different sequences
Number of 'unknown' hits 0
Number of false positive hits 7 in 7 different sequences
Number of false negative sequences 14
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 92.39 %
Recall (true positives / (true positives + false negatives)) 85.86 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 85 sequences 

CML45_ARATH (Q9MBG5    ), FILA2_HUMAN (Q5D862    ), FILA2_MOUSE (Q2VIS4    ), 

FILA_HUMAN  (P20930    ), HORN_HUMAN  (Q86YZ3    ), HORN_MOUSE  (Q8VHD8    ), 
M126_CHICK  (P28318    ), RPTN_HUMAN  (Q6XPR3    ), RPTN_MOUSE  (P97347    ), 
S100B_BOVIN (P02638    ), S100B_HUMAN (P04271    ), S100B_MOUSE (P50114    ), 
S100B_RABIT (Q6YNR6    ), S100B_RAT   (P04631    ), S100G_BOVIN (P02633    ), 
S100G_HORSE (Q865V3    ), S100G_HUMAN (P29377    ), S100G_MOUSE (P97816    ), 
S100G_PIG   (P02632    ), S100G_RAT   (P02634    ), S100P_HUMAN (P25815    ), 
S100Z_HUMAN (Q8WXG8    ), S10A1_BOVIN (P02639    ), S10A1_HUMAN (P23297    ), 
S10A1_MISFO (Q7LZT1    ), S10A1_MOUSE (P56565    ), S10A1_PONAB (Q5RC36    ), 
S10A1_RAT   (P35467    ), S10A2_BOVIN (P10462    ), S10A2_HUMAN (P29034    ), 
S10A3_HUMAN (P33764    ), S10A3_MOUSE (P62818    ), S10A3_RAT   (P62819    ), 
S10A4_BOVIN (P35466    ), S10A4_CANLF (Q9TV56    ), S10A4_HUMAN (P26447    ), 
S10A4_MOUSE (P07091    ), S10A4_RAT   (P05942    ), S10A5_HUMAN (P33763    ), 
S10A5_MOUSE (P63084    ), S10A5_RAT   (P63083    ), S10A6_CHICK (Q98953    ), 
S10A6_HORSE (O77691    ), S10A6_HUMAN (P06703    ), S10A6_MOUSE (P14069    ), 
S10A6_PIG   (Q2EN75    ), S10A6_RABIT (P30801    ), S10A6_RAT   (P05964    ), 
S10A7_BOVIN (Q28050    ), S10A7_HORSE (Q14ST5    ), S10A7_HUMAN (P31151    ), 
S10A8_BOVIN (P28782    ), S10A8_HUMAN (P05109    ), S10A8_MOUSE (P27005    ), 
S10A8_RAT   (P50115    ), S10A9_BOVIN (P28783    ), S10A9_HUMAN (P06702    ), 
S10A9_MOUSE (P31725    ), S10A9_RABIT (P50117    ), S10A9_RAT   (P50116    ), 
S10AA_BOVIN (P60902    ), S10AA_CHICK (P27003    ), S10AA_HUMAN (P60903    ), 
S10AA_MACMU (P62504    ), S10AA_MOUSE (P08207    ), S10AA_PIG   (P04163    ), 
S10AA_RABIT (Q6SQH4    ), S10AA_RAT   (P05943    ), S10AB_CHICK (P24479    ), 
S10AB_HUMAN (P31949    ), S10AB_MOUSE (P50543    ), S10AB_PIG   (P31950    ), 
S10AB_RABIT (P24480    ), S10AB_RAT   (Q6B345    ), S10AC_BOVIN (P79105    ), 
S10AC_HUMAN (P80511    ), S10AC_PIG   (P80310    ), S10AC_RABIT (O77791    ), 
S10AG_BOVIN (Q0VCM0    ), S10AG_HUMAN (Q96FQ6    ), S10I_ICTPU  (Q91061    ), 
S1A7A_HUMAN (Q86SG5    ), TRHY_HUMAN  (Q07283    ), TRHY_RABIT  (P37709    ), 
TRHY_SHEEP  (P22793    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 14 sequences 

S10AA_XENLA (P27004    ), S10AD_BOVIN (P79342    ), S10AD_HUMAN (Q99584    ), 

S10AD_MOUSE (P97352    ), S10AE_BOVIN (Q3MHP3    ), S10AE_HUMAN (Q9HCY8    ), 
S10AE_MOUSE (Q9D2Q8    ), S115A_GORGO (A7K6Y8    ), S115A_MOUSE (Q6S5I3    ), 
S115A_PONAB (A7K6Y9    ), S1A7B_HUMAN (Q5SY68    ), TCHL1_BOVIN (A6QP92    ), 
TCHL1_HUMAN (Q5QJ38    ), TCHL1_MOUSE (Q9D3P1    )
» more

UniProtKB/Swiss-Prot
False positive sequences		 7 sequences 

CABP7_HUMAN (Q86V35    ), CABP7_MOUSE (Q91ZM8    ), CABP7_PAPAN (Q866X0    ), 

CABP7_RAT   (Q66H96    ), CABP8_HUMAN (Q9BXU9    ), CABP8_MOUSE (Q9JJG7    ), 
CABP8_RAT   (Q06BI3    )
» more

PDB
[Detailed view]		 170 PDB

1A03; 1A4P; 1B1G; 1B4C; 1BOC; 1BOD; 1BT6; 1CB1; 1CDN; 1CFP; 1CLB; 1CNP; 1D1O; 1DT7; 1E8A; 1GQM; 1HT9; 1IG5; 1IGV; 1IRJ; 1J55; 1JWD; 1K2H; 1K8U; 1K96; 1K9K; 1K9P; 1KCY; 1KQV; 1KSM; 1KSO; 1M31; 1MHO; 1MQ1; 1MR8; 1MWN; 1N65; 1NSH; 1ODB; 1OZO; 1PSB; 1PSR; 1QLK; 1QLS; 1SYM; 1UWO; 1XK4; 1XYD; 1ZFS; 2BCA; 2BCB; 2CNP; 2H61; 2JPT; 2JTT; 2K2F; 2K7O; 2KAX; 2KAY; 2KBM; 2L0P; 2L50; 2L51; 2LHL; 2LLS; 2LLT; 2LLU; 2LNK; 2LP2; 2LP3; 2LUC; 2LUX; 2M1K; 2M3W; 2M49; 2M9G; 2MAZ; 2MJW; 2MRD; 2PRU; 2PSR; 2Q91; 2RGI; 2WC8; 2WCB; 2WCE; 2WCF; 2WND; 2WOR; 2WOS; 3C1V; 3CGA; 3CR2; 3CR4; 3CR5; 3CZT; 3D0Y; 3D10; 3GK1; 3GK2; 3GK4; 3HCM; 3ICB; 3IQO; 3IQQ; 3KO0; 3LK0; 3LK1; 3LLE; 3M0W; 3NSI; 3NSK; 3NSL; 3NSO; 3NXA; 3PSR; 3RLZ; 3RM1; 3ZWH; 4AQI; 4AQJ; 4CFQ; 4CFR; 4DIR; 4DRW; 4DUQ; 4ETO; 4FQO; 4FTG; 4GGF; 4HRE; 4HRG; 4HRH; 4HSZ; 4ICB; 4P2Y; 4PCW; 4PDZ; 4PE0; 4PE1; 4PE4; 4PE7; 4XJK; 4XYN; 4YBH; 5CSF; 5CSI; 5CSJ; 5CSN; 5D7F; 5DKN; 5DKQ; 5DKR; 5ER4; 5ER5; 5HLO; 5HLV; 5HYD; 5I8N; 5K89; 5LPU; 5W1F; 6DS2; 6T58; 6WN7; 6ZDY; 7NMI; 7PSP; 7PSQ; 7UI5
» more