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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00335


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PURL: https://purl.expasy.org/prosite/signature/PS00335

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General information about the entry

Entry name [info] PARATHYROID
Accession [info] PS00335
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-1990 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00296

Name and characterization of the entry

Description [info] Parathyroid hormone family signature.
Pattern [info] 
V-S-E-x-Q-x(2)-H-x(2)-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 22 in 22 different sequences
Number of true positive hits 18 in 18 different sequences
Number of 'unknown' hits 0
Number of false positive hits 4 in 4 different sequences
Number of false negative sequences 0
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 81.82 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 18 sequences 

PTHR_BOVIN  (P58073), PTHR_CANLF  (P52211), PTHR_CHICK  (P17251), 

PTHR_HUMAN  (P12272), PTHR_MOUSE  (P22858), PTHR_RABIT  (Q9GLC7), 
PTHR_RAT(P13085), PTHR_SHEEP  (Q9GK30), PTHY_BOVIN  (P01268), 
PTHY_CANLF  (P52212), PTHY_CHICK  (P15743), PTHY_FELCA  (Q9GL67), 
PTHY_HORSE  (Q27IM2), PTHY_HUMAN  (P01270), PTHY_MACFA  (Q9XT35), 
PTHY_MOUSE  (Q9Z0L6), PTHY_PIG(P01269), PTHY_RAT(P04089)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

PTHR_HORSE  (Q9GMB7)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			4 sequences
			


			
AKT6_ARATH  (Q8GXE6), B3GT4_HUMAN (O96024), SAR1_CRYNB  (P0CR31), 

			
SAR1_CRYNJ  (P0CR30)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			27 PDB
			


			pdb_00001bwx; pdb_00001bzg; pdb_00001et1; pdb_00001fvy; pdb_00001hph; pdb_00001hpy; pdb_00001hth; pdb_00001zwa; pdb_00001zwb; pdb_00001zwc; pdb_00002l1x; pdb_00003ffd; 
			
				pdb_00007vvj; pdb_00007vvk; pdb_00007vvl; pdb_00007vvm; pdb_00007vvn; pdb_00007vvo; pdb_00007y36; pdb_00008flq; pdb_00008flr; pdb_00008ha0; pdb_00008haf; pdb_00008hao; 
				pdb_00008t5f; pdb_00009jr2; pdb_00009jr3
			
			

			» more