PROSITE entry PS00346

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PURL: https://purl.expasy.org/prosite/signature/PS00346

Direct ScanProsite submission

General information about the entry

Entry name [info]	ETS_DOMAIN_2
Accession [info]	PS00346
Entry type [info]	PATTERN
Date [info]	01-NOV-1990 CREATED; 01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00374

Name and characterization of the entry

Description [info]	Ets-domain signature 2.
Pattern [info]	[RKHN]-x(2)-M-x-Y-[DENQ]-x-[LIVM]-[STAG]-R-[STAG]-[LI]-R-x-Y.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	96 in 96 different sequences
Number of true positive hits	96 in 96 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	9
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	91.43 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info]	1
Version [info]	2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

96 sequences

AST1_CAEEL  (Q22355), E74EA_DROME (P20105), E74EB_DROME (P11536),

E74EF_DROVI (Q7M3M6), ELF1_BOVIN  (A0JN51), ELF1_HUMAN  (P32519), 
ELF1_MOUSE  (Q60775), ELF2_HUMAN  (Q15723), ELF2_MOUSE  (Q9JHC9), 
ELF4_HUMAN  (Q99607), ELF4_MOUSE  (Q9Z2U4), ELF5_BOVIN  (Q58DT0), 
ELF5_HUMAN  (Q9UKW6), ELF5_MOUSE  (Q8VDK3), ELG_DROME   (Q04688), 
ELK1_HUMAN  (P19419), ELK1_MOUSE  (P41969), ELK1_RAT(A4GTP4), 
ELK3_HUMAN  (P41970), ELK3_MOUSE  (P41971), ELK4_HUMAN  (P28324), 
ELK4_MOUSE  (P41158), ERFL_HUMAN  (A0A1W2PQ73), ERF_HUMAN   (P50548), 
ERF_MOUSE   (P70459), ERG_CHICK   (Q90837), ERG_HUMAN   (P11308), 
ERG_LYTVA   (Q01414), ERG_MOUSE   (P81270), ET96B_DROME (Q8MRW5), 
ETS1A_CHICK (P13474), ETS1A_XENLA (P18755), ETS1B_CHICK (P15062), 
ETS1B_XENLA (P18756), ETS1_HUMAN  (P14921), ETS1_MOUSE  (P27577), 
ETS1_RAT(P41156), ETS2A_XENLA (P19102), ETS2B_XENLA (Q91712), 
ETS2_BOVIN  (A1A4L6), ETS2_CHICK  (P10157), ETS2_HUMAN  (P15036), 
ETS2_LYTVA  (P29773), ETS2_MOUSE  (P15037), ETS3_DROME  (P29774), 
ETS4_CAEEL  (A8WFJ9), ETS4_DROME  (P29775), ETS5_CAEEL  (Q18579), 
ETS6_DROME  (P29776), ETV1_BOVIN  (Q2KIC2), ETV1_HUMAN  (P50549), 
ETV1_MOUSE  (P41164), ETV2_HUMAN  (O00321), ETV2_MOUSE  (P41163), 
ETV3L_HUMAN (Q6ZN32), ETV3_ATEGE  (A2D4Z7), ETV3_GORGO  (A1YF15), 
ETV3_HUMAN  (P41162), ETV3_MOUSE  (Q8R4Z4), ETV3_PANPA  (A1YG91), 
ETV3_PANTR  (A2T762), ETV4_DANRE  (Q9PUQ1), ETV4_HUMAN  (P43268), 
ETV4_MOUSE  (P28322), ETV5_HUMAN  (P41161), ETV5_MOUSE  (Q9CXC9), 
ETV6_BOVIN  (Q0VC65), ETV6_HUMAN  (P41212), ETV6_MOUSE  (P97360), 
ETV7_HUMAN  (Q9Y603), FEV_DANRE   (A3FEM2), FEV_HUMAN   (Q99581), 
FEV_MOUSE   (Q8QZW2), FEV_RAT (O70132), FLI1_BOVIN  (Q29RS8), 
FLI1_HUMAN  (Q01543), FLI1_MOUSE  (P26323), FLI1_XENLA  (P41157), 
GABPA_HUMAN (Q06546), GABPA_MOUSE (Q00422), MYBE_AVILE  (P01105), 
PNT_DROME   (P51023), POK_DROME   (Q01842), SPDEF_HUMAN (O95238), 
SPDEF_MOUSE (Q9WTP3), SPI1_HUMAN  (P17947), SPI1_MOUSE  (P17433), 
SPI1_PIG(Q6PKU1), SPI1_RAT(Q6BDS1), SPIB_HUMAN  (Q01892), 
SPIB_MOUSE  (O35906), SPIB_PALPA  (Q9I8M6), SPIB_RAT(Q5EBA3), 
SPIC_BOVIN  (Q1RML4), SPIC_HUMAN  (Q8N5J4), SPIC_MOUSE  (Q6P3D7)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

9 sequences

EHF_BOVIN   (Q32LN0), EHF_HUMAN   (Q9NZC4), EHF_MOUSE   (O70273),

EHF_PANPA   (A1YG61), EHF_PANTR   (A2T737), ELF3_HUMAN  (P78545), 
ELF3_MOUSE  (Q3UPW2), ELF3_RAT(Q4V7E1), ETS7_CAEEL  (O01519)

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PDB
[Detailed view]

115 PDB

1AWC; 1BC7; 1BC8; 1DUX; 1FLI; 1GVJ; 1HBX; 1K6O; 1K78; 1K79; 1K7A; 1MD0; 1MDM; 1PUE; 1R36; 1WWX; 1YO5; 2DAO; 2LF7; 2LF8; 2MD5; 2NNY; 2STT; 2STW; 2YPR; 3MFK; 3RI4; 3WTS; 3WTT; 3WTU; 3WTV; 3WTW; 3WTX; 3WTY; 3WTZ; 3WU0; 3WU1; 3ZP5; 4AVP; 4BNC; 4BQA; 4CO8; 4IRG; 4IRH; 4IRI; 4L0Y; 4L0Z; 4L18; 4LG0; 4MHG; 4UNO; 4UUV; 5E8G; 5E8I; 5ILS; 5ILU; 5ILV; 5JVT; 5W3G; 5YBC; 5YBD; 5ZMC; 6DA1; 6DAT; 6VG2; 6VG8; 6VGD; 6VGE; 6VGG; 7JSA; 7JSL; 8BZM; 8E3K; 8E3R; 8E4H; 8E5Y; 8E66; 8E67; 8EBH; 8EE9; 8EJ6; 8EJ8; 8EK3; 8EK8; 8EKJ; 8EKU; 8EKV; 8EKZ; 8EM9; 8EMD; 8ENG; 8EO1; 8EO4; 8EQG; 8EQK; 8EQL; 8EVH; 8EVI; 8EVJ; 8SMH; 8SMJ; 8SP1; 8T9U; 8UFF; 8UFK; 8UFZ; 8UHK; 8V9N; 8VDH; 8VDI; 9CP6; 9MWY; 9MX8; 9MX9; 9MXA
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