PROSITE entry PS00354

View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission

General information about the entry

Entry name [info]	HMGI_Y
Accession [info]	PS00354
Entry type [info]	PATTERN
Date [info]	01-NOV-1990 CREATED; 01-OCT-1993 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00306

Name and characterization of the entry

Description [info]	HMG-I and HMG-Y DNA-binding domain (A+T-hook).
Pattern [info]	[AT]-x(1,2)-[RK](2)-[GP]-R-G-R-P-[RK]-x.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.

Total number of hits	39 in 27 different sequences
Number of true positive hits	32 in 20 different sequences
Number of 'unknown' hits	0
Number of false positive hits	7 in 7 different sequences
Number of false negative sequences	6
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	82.05 %
Recall (true positives / (true positives + false negatives))	84.21 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	3
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	20 sequences AFFL_DROER (B3NAM7), AFFL_DROGR (B4JQ42), AFFL_DROME (Q9VQI9), AFFL_DROMO (B4KFE1), AFFL_DROPS (Q29KG4), AFFL_DROVI (B4LV24), AFFL_DROWI (B4MUE1), AFFL_DROYA (B4NXA8), HMGA1_CANLF (Q6URC2), HMGA1_CRIGR (Q9QXP3), HMGA1_HUMAN (P17096), HMGA1_MOUSE (P17095), HMGA1_RAT (Q8K585), HMGA2_HUMAN (P52926), KMT2C_HUMAN (Q8NEZ4), KMT2C_MOUSE (Q8BRH4), MYNN_DANRE (Q7ZVR6), PATZ1_HUMAN (Q9HBE1), PATZ1_MOUSE (Q5NBY9), PRH_PETCR (P48786) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	6 sequences AFFL_DROAN (B3MLB7), CHIF_DROME (Q9NK54), HMGA1_CHITE (Q23794), HMGA2_MOUSE (P52927), LI15B_CAEEL (Q27395), SFC3_SCHPO (Q9UST7) » more
UniProtKB/Swiss-Prot False positive sequences	7 sequences BRLF1_SHV21 (Q01012), CE087_XENLA (Q5XG50), HQ1_COXBU (Q45881), KMT2A_HUMAN (Q03164), KMT2A_MOUSE (P55200), SLX4_PYRO7 (A4R1T1), WHIB7_MYCS2 (A0QTT1) » more
PDB [Detailed view]	2 PDB 2EZD; 2EZE