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Entry: PS00374

General information about the entry

Entry name [info] MGMT
Accession [info] PS00374
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-NOV-1990 DATA UPDATE;
02-JUN-2021 INFO UPDATE.
PROSITE Doc. [info] PDOC00320
Associated ProRule [info] PRU10017

Name and characterization of the entry

Description [info] Methylated-DNA--protein-cysteine methyltransferase active site.
Pattern [info] 
[LIVMF]-P-C-H-R-[LIVMF](2).

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2021_03 which contains 565'254 sequence entries.


Total number of hits 65 in 65 different sequences
Number of true positive hits 53 in 53 different sequences
Number of 'unknown' hits 0
Number of false positive hits 12 in 12 different sequences
Number of false negative sequences 2
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 81.54 %
Recall (true positives / (true positives + false negatives)) 96.36 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 53 sequences 

ADAB_BACSU  (P19220    ), ADA_ECOLI   (P06134    ), ADA_SALTY   (P26189    ), 

MGMT_CANAL  (Q5A0Y8    ), MGMT_CANGA  (Q6FNR0    ), MGMT_CANLF  (Q6TDU1    ), 
MGMT_CRIGR  (P26186    ), MGMT_HUMAN  (P16455    ), MGMT_KLULA  (Q6CPW2    ), 
MGMT_LODEL  (A5E7M8    ), MGMT_MIMIV  (Q5UNU9    ), MGMT_MOUSE  (P26187    ), 
MGMT_PICST  (A3LZM4    ), MGMT_RAT    (P24528    ), MGMT_YEAS7  (A6ZXD3    ), 
MGMT_YEAST  (P26188    ), OGT_ARCFU   (O27970    ), OGT_BACSU   (P11742    ), 
OGT_ECOLI   (P0AFH0    ), OGT_HAEIN   (P44687    ), OGT_METAC   (Q8TI34    ), 
OGT_METBF   (Q46EW4    ), OGT_METJA   (Q58924    ), OGT_METMA   (Q8PY44    ), 
OGT_METS5   (A4YH39    ), OGT_METTH   (O26715    ), OGT_METVM   (C9RE37    ), 
OGT_MYCBO   (P0A697    ), OGT_MYCLE   (P52982    ), OGT_MYCPA   (Q9ZET8    ), 
OGT_MYCTO   (P9WJW4    ), OGT_MYCTU   (P9WJW5    ), OGT_PYRAB   (Q9V1N7    ), 
OGT_PYRAE   (O93728    ), OGT_PYRFU   (Q8TZV2    ), OGT_PYRHO   (O59499    ), 
OGT_PYRSN   (F4HK38    ), OGT_SACS2   (Q97VW7    ), OGT_SALTI   (P0A2U1    ), 
OGT_SALTY   (P0A2U0    ), OGT_SHIFL   (P0AFH1    ), OGT_SULAC   (Q4J9C6    ), 
OGT_SULIA   (C3N1B4    ), OGT_SULIK   (C4KKV8    ), OGT_SULIL   (C3MKT6    ), 
OGT_SULIM   (C3MUC6    ), OGT_SULIN   (C3NMY2    ), OGT_SULIY   (C3N9B4    ), 
OGT_SULTO   (Q973C7    ), OGT_THEBM   (F0LIT8    ), OGT_THEGJ   (C5A3L5    ), 
OGT_THEKO   (O74023    ), OGT_THESM   (C6A382    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 2 sequences 

ATL1_SCHPO  (Q9UTN9    ), OGT_METKA   (Q8TZ11    )


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			1 sequence
			


			
MGMT_BOVIN  (P29177    )


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			12 sequences
			


			
CFA65_HUMAN (Q6ZU64    ), KBTBC_HUMAN (Q3ZCT8    ), KBTBC_MOUSE (Q9D618    ), 

			
KL40A_DANRE (B3DIV9    ), KL40B_DANRE (E9QJ30    ), KLH40_HUMAN (Q2TBA0    ), 
KLH40_MOUSE (Q9D783    ), KLH40_XENLA (Q5U504    ), KLH40_XENTR (Q5EB39    ), 
KLH41_HUMAN (O60662    ), KLH41_MOUSE (A2AUC9    ), KLH41_RAT   (Q9ER30    )


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			18 PDB
			


			1EH6; 1EH7; 1EH8; 1MGT; 1QNT; 1SFE; 1T39; 1WRJ; 1YFH; 2G7H; 4BHB; 4BHC; 
			
				4WX9; 4WXC; 4WXD; 4ZYE; 4ZYG; 6GA0
			
			

			» more

				
	





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