annotation rule: PRU10017

General rule information [?]

Accession PRU10017
Dates 16-OCT-2006 (Created)
19-JUN-2017 (Last updated, Version 4)
Data class Domain
Predictors PROSITE; PS00374; MGMT
Name Methylated-DNA--protein-cysteine methyltransferase active site
Function Undefined.

Propagated annotation [?]


Description [?]

+ AltName: Full=Methylated-DNA--[protein]-cysteine S-methyltransferase; EC=2.1.1.63;

Comments [?]

Catalytic activity DNA (containing 6-O-methylguanine) + protein L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine.
DNA (containing 4-O-methylthymine) + protein L-cysteine = DNA (without 4-O-methylthymine) + protein S-methyl-L-cysteine.

Features [?]

From: PS00374
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     3     3       Nucleophile; methyl group acceptor        

Additional information [?]

Size range unlimited amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q4J9C6 (OGT_SULAC)
Scope Eukaryota
Bacteria
Archaea
Viruses

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]