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annotation rule: PRU10017

General rule information [?]

Accession PRU10017
Dates 16-OCT-2006 (Created)
22-NOV-2019 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS00374; MGMT
Name Methylated-DNA--protein-cysteine methyltransferase active site
Function Undefined.

Propagated annotation [?]


Description [?]

+ AltName: Full=Methylated-DNA--[protein]-cysteine S-methyltransferase; EC 2.1.1.63;

Comments [?]

Catalytic activity RHEA:24000: a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = a 2'-deoxyguanosine in DNA + S-methyl-L-cysteinyl-[protein]
EC 2.1.1.63
RHEA:53428: a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]
EC 2.1.1.63

Features [?]

From: PS00374
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     3     3       Nucleophile; methyl group acceptor        

Additional information [?]

Size range unlimited amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q4J9C6 (OGT_SULAC)
Scope
Eukaryota
Bacteria
Archaea
Viruses

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]