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PROSITE entry PS00387


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General information about the entry

Entry name [info] PPASE
Accession [info] PS00387
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00325

Name and characterization of the entry

Description [info] Inorganic pyrophosphatase signature.
Pattern [info]
D-[SGDN]-D-[PE]-[LIVMF]-D-[LIVMGAC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 259 in 258 different sequences
Number of true positive hits 128 in 128 different sequences
Number of 'unknown' hits 1
Number of false positive hits 130 in 129 different sequences
Number of false negative sequences 8
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 49.61 %
Recall (true positives / (true positives + false negatives)) 94.12 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] magnesium at position 1
Site [info] magnesium at position 3
Site [info] magnesium at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
128 sequences

IPYR1_ARATH (Q93V56), IPYR1_CHLRE (Q93Y52), IPYR1_PSESM (Q889M7), 
IPYR2_ARATH (P21216), IPYR2_CHLRE (Q949J1), IPYR2_HUMAN (Q9H2U2), 
IPYR2_MOUSE (Q91VM9), IPYR2_PSESM (Q87WD6), IPYR2_SCHPO (P87118), 
IPYR2_YEAST (P28239), IPYR3_ARATH (O82793), IPYR4_ARATH (Q9LFF9), 
IPYR5_ARATH (O82597), IPYR6_ARATH (Q9LXC9), IPYR_AERPE  (Q9YBA5), 
IPYR_AGRFC  (Q8UC37), IPYR_AQUAE  (O67501), IPYR_AQUPY  (Q8GQS5), 
IPYR_BACP3  (P19514), IPYR_BARBK  (P51064), IPYR_BOVIN  (P37980), 
IPYR_BRUME  (P65744), IPYR_BRUSU  (P65745), IPYR_BUCAI  (P57190), 
IPYR_BUCAP  (Q8KA31), IPYR_BUCBP  (P59417), IPYR_CAEEL  (Q18680), 
IPYR_CAMJE  (Q9PHM9), IPYR_CANAL  (P83777), IPYR_CANGA  (Q6FRB7), 
IPYR_CHLCV  (Q821T4), IPYR_CHLMU  (Q9PLF1), IPYR_CHLT2  (B0B8Z8), 
IPYR_CHLTA  (Q3KKS0), IPYR_CHLTB  (B0BAM7), IPYR_CHLTR  (O84777), 
IPYR_COREF  (Q8FMF8), IPYR_CORGL  (Q8NM79), IPYR_DEBHA  (Q6BWA5), 
IPYR_DICDI  (Q54PV8), IPYR_DROME  (O77460), IPYR_ECO57  (P0A7B0), 
IPYR_ECOL6  (Q8FAG0), IPYR_ECOLI  (P0A7A9), IPYR_EMENI  (Q5B912), 
IPYR_ENCCU  (Q8SR69), IPYR_EREGS  (Q757J8), IPYR_GEOSE  (O05724), 
IPYR_HAEDU  (Q7VPC0), IPYR_HAEIN  (P44529), IPYR_HALH5  (Q9KCG7), 
IPYR_HALSA  (Q9HSF3), IPYR_HELPJ  (Q9ZLL5), IPYR_HELPY  (P56153), 
IPYR_HORVV  (O23979), IPYR_HUMAN  (Q15181), IPYR_KLULA  (P13998), 
IPYR_LEGPN  (O34955), IPYR_LEIXX  (Q6ACP7), IPYR_MACFA  (Q4R543), 
IPYR_MAIZE  (O48556), IPYR_MALP2  (Q8EVW9), IPYR_METAC  (Q8TMI3), 
IPYR_METKA  (Q8TVE2), IPYR_METMA  (Q8PWY5), IPYR_METTH  (O26363), 
IPYR_MOUSE  (Q9D819), IPYR_MYCBO  (P65747), IPYR_MYCGE  (P47593), 
IPYR_MYCLE  (O69540), IPYR_MYCPN  (P75250), IPYR_MYCPU  (Q98Q96), 
IPYR_MYCTO  (P9WI54), IPYR_MYCTU  (P9WI55), IPYR_NANEQ  (Q74MY6), 
IPYR_NEIMA  (Q9JVG3), IPYR_NEIMB  (Q9K0G4), IPYR_NEUCR  (Q6MVH7), 
IPYR_NOSS1  (P80562), IPYR_ORYSI  (A2X8Q3), IPYR_ORYSJ  (Q0DYB1), 
IPYR_PASMU  (P57918), IPYR_PICPA  (O13505), IPYR_PICTO  (Q6KZB3), 
IPYR_PLAF7  (O77392), IPYR_PONAB  (Q5R8T6), IPYR_PSEAE  (Q9HWZ6), 
IPYR_PSEAO  (P58733), IPYR_PSEPK  (Q88QF6), IPYR_PYRAB  (Q9UY24), 
IPYR_PYRFU  (Q8U438), IPYR_PYRHO  (O59570), IPYR_RALN1  (Q8XWX1), 
IPYR_RHILO  (Q98ER2), IPYR_RHIME  (Q92LH1), IPYR_RHORT  (Q9RGQ1), 
IPYR_RICBR  (Q1RIN6), IPYR_RICCN  (Q92H74), IPYR_RICFE  (Q4UKW0), 
IPYR_RICPR  (Q9ZCW5), IPYR_RICTY  (Q68WE9), IPYR_SACS2  (Q97W51), 
IPYR_SALTI  (P65749), IPYR_SALTY  (P65748), IPYR_SCHPO  (P19117), 
IPYR_SOLTU  (Q43187), IPYR_STRCO  (Q9X8I9), IPYR_SULAC  (P50308), 
IPYR_SULTO  (Q974Y8), IPYR_SYNY3  (P80507), IPYR_THEAC  (P37981), 
IPYR_THEKO  (Q5JIY3), IPYR_THELN  (P77992), IPYR_THET8  (P38576), 
IPYR_THEVB  (Q8DHR2), IPYR_THEVO  (Q979E6), IPYR_UREPA  (Q9PQH6), 
IPYR_VIBCH  (Q9KP34), IPYR_VIBPA  (Q87SW1), IPYR_VIBVU  (Q8DE89), 
IPYR_VIBVY  (Q7MPD2), IPYR_WIGBR  (Q8D274), IPYR_XYLFA  (P65750), 
IPYR_XYLFT  (P65751), IPYR_YARLI  (Q6C1T4), IPYR_YEAST  (P00817), 
IPYR_YERPE  (Q8ZB98), IPYR_ZYGBA  (Q9C0T9)
» more

UniProtKB/Swiss-Prot
False negative sequences
8 sequences

IPYR_BRADU  (Q89WY0), IPYR_CAUVC  (Q9AC20), IPYR_CHLPN  (Q9Z6Y8), 
IPYR_GLUOX  (O05545), IPYR_LEPIC  (Q72MG4), IPYR_LEPIN  (Q8EZ21), 
IPYR_XANAC  (Q8PH18), IPYR_XANCP  (Q8P5M4)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
5 sequences

IPYR_BLAVI  (P82992), IPYR_CYAPA  (P80887), IPYR_EUGGR  (P81987), 
IPYR_NITV2  (P19371), IPYR_OCHDN  (P81988)
» more

UniProtKB/Swiss-Prot
'Unknown' sequences
1 sequence

JD1_AMOJI   (K7ZGS2)

		
UniProtKB/Swiss-Prot
False positive sequences
129 sequences

AER3_AERHY  (Q06305), AER4_AERHY  (Q06303), AER5_AERHY  (Q06306), 
AERA_AERHY  (P09167), AFTD_MYCS2  (A0QPD4), AGPA_RHIME  (Q9X4Y1), 
ARCA_HALS3  (B0R9X5), AROC_ACICJ  (A5FY49), ASP36_ARATH (Q4V3D2), 
BBS5_CAEEL  (Q21626), BR11_AMOCU  (E1AWD4), BR11_AMOMA  (E1B240), 
BR12_AMOCU  (E1AWD5), BR12_AMOMA  (E1B241), BR15_AMOCU  (E1B228), 
BRA_AMOLO   (A0SN38), BRB_AMOLO   (A0SN42), BYE1_PICGU  (A5DDB7), 
C42_NPVOP   (P24653), CBAB_COMTE  (Q44257), CPL3_ARATH  (Q8LL04), 
CSM3_ASPFU  (A4DA84), CSM3_NEOFI  (A1D9E6), CSM3_NEUCR  (Q7SHE8), 
CYAD_DICDI  (Q55F68), DCN1_YARLI  (Q6C0B6), DIG1_CAEEL  (Q09165), 
DNAJ_BORBU  (P28616), DNAJ_BORGP  (Q661A4), DRE2_LACTC  (C5DJL0), 
END4_GEOSL  (Q74FS7), ENT5_YEAST  (Q03769), FAU1_HALMA  (Q5V0I9), 
FAU1_NATPD  (Q3ITR7), FBD14_ARATH (Q9FNI9), FIBER_BPT1  (Q6XQB2), 
FRMD3_HUMAN (A2A2Y4), FRMD3_PONAB (Q5R803), GDIR2_BOVIN (Q9TU03), 
GLK_BRUA1   (B2SC34), GLK_BRUA2   (Q2YJN9), GLK_BRUAB   (P0CB37), 
GLK_BRUME   (Q8YDC6), GLK_BRUSU   (Q8FV09), GLMM_SALAI  (A8M4B8), 
GLMM_SALTO  (A4XBI5), GSH1_VIBCH  (Q9KUG5), GYP7_DEBHA  (Q6BU76), 
HAP1_YEAS1  (B3RHD9), HAP1_YEAS2  (C7GQY3), HAP1_YEAS7  (A7A1D7), 
HAP1_YEAS8  (C8ZDL9), HAP1_YEASK  (G2WJ80), HAP1_YEAST  (P0CE41), 
HAP1_YEASX  (P0CS82), HETM_NOSS1  (P37693), J1MT1_AMOMA (E1B245), 
JIP5_ASPFU  (Q4WNA1), KCMB3_HUMAN (Q9NPA1), KN12C_ORYSJ (Q5W6L9), 
LCSA_PURLI  (A0A179H164), MAK5_AJECN  (A6R9U4), MAP22_ASPTN (Q0CL94), 
MCA1_SCHPO  (O74477), MCL1A_DANRE (Q9PSI9), MCM9_XENTR  (F6RIX4), 
MNMA_NOCSJ  (A1SMB0), MTGA_PSEF5  (Q4K4C2), MYLKE_DICDI (Q54PB4), 
NAV1_HUMAN  (Q8NEY1), NAV1_MOUSE  (Q8CH77), NHAA1_RHOJR (Q0SG15), 
NPR3_DEBHA  (Q6BQU8), OBG_MYCGA   (Q7NB30), OPF15_ARATH (Q9SJ45), 
OTSA_MYCSK  (A1UM30), OTSA_MYCSS  (Q1B321), PA24A_HORSE (O77793), 
PA24A_HUMAN (P47712), PA24A_PONAB (Q5R8A5), PA24A_RABIT (Q9TT38), 
PA24A_RAT   (P50393), PFMAD_PESFW (W3X7K0), PPN1_NEUCR  (Q9P3S1), 
PRMA_ACIAD  (Q6F9P9), PSF2_PHANO  (Q0UTE1), PUX8_ARATH  (F4JPR7), 
RIBA1_ORYSJ (Q6Z234), RIMO_BACFN  (Q5LCF8), RIMO_BACFR  (Q64TK5), 
RPN8_YEAST  (Q08723), RPOB_ALKMQ  (A6TWJ0), RPOC_ANADE  (Q2II85), 
RPOC_ANADF  (A7HCH6), RPOC_ANASK  (B4UDT1), SKL1_ARATH  (Q9LW20), 
SUMO1_ARATH (P55852), SUMO1_ORYSJ (P55857), SUMO2_ARATH (Q9FLP6), 
SUMO4_ARATH (Q9FKC5), SUMO7_ARATH (Q3E8A8), T2EA_YEAST  (P36100), 
TRA4_CAEEL  (Q20709), TREA_CANAX  (P52494), TUBE2_BPT7  (P03747), 
ULAC_ECO57  (P69821), ULAC_ECOL6  (Q8FAJ0), ULAC_ECOLI  (P69820), 
ULAC_SALCH  (Q57GJ7), ULAC_SALPA  (Q5PJ64), ULAC_SALTI  (Q8Z170), 
ULAC_SALTY  (Q8ZK88), ULAC_SHIBS  (Q31TC6), ULAC_SHIDS  (Q328K2), 
ULAC_SHIFL  (Q83P28), ULAC_SHISS  (Q3YUF3), UTP10_USTMA (Q4P937), 
WASC2_MOUSE (Q6PGL7), XRN2_USTMA  (Q4P149), Y495_SALRD  (Q2S591), 
YCEI_ECO57  (P0A8X3), YCEI_ECOL6  (Q8CW58), YCEI_ECOLI  (P0A8X2), 
YCEI_SHIBS  (Q31ZB2), YCEI_SHIFL  (Q83LI9), YCEI_SHISS  (Q3Z360), 
YCF2_CHLSC  (A6MMG6), YP93_CAEEL  (Q09475), YTZ4_AGRVI  (P70796)
» more

PDB
[Detailed view]
59 PDB

1E6A; 1E9G; 1FAJ; 1HUJ; 1HUK; 1I40; 1I6T; 1IGP; 1INO; 1IPW; 1JFD; 1M38; 1MJW; 1MJZ; 1OBW; 1QEZ; 1SXV; 1TWL; 1UDE; 1WCF; 1WGI; 1WGJ; 1YGZ; 1YPP; 2AU6; 2AU7; 2AU8; 2AU9; 2AUU; 2BQX; 2BQY; 2EIP; 2IHP; 2IK0; 2IK1; 2IK9; 2PRD; 2UXS; 3D53; 3EMJ; 4ECP; 4LUG; 4UM4; 4XEL; 4Z70; 4Z71; 4Z72; 4Z73; 4Z74; 5KDE; 5KDF; 5LS0; 5TEA; 5WRU; 6C45; 6WE5; 7BTN; 7CMO; 8PRK
» more