PROSITE logo

PROSITE entry PS00387


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] PPASE
Accession [info] PS00387
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00325

Name and characterization of the entry

Description [info] Inorganic pyrophosphatase signature.
Pattern [info] 
D-[SGDN]-D-[PE]-[LIVMF]-D-[LIVMGAC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 259 in 258 different sequences
Number of true positive hits 128 in 128 different sequences
Number of 'unknown' hits 1
Number of false positive hits 130 in 129 different sequences
Number of false negative sequences 8
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 49.61 %
Recall (true positives / (true positives + false negatives)) 94.12 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] magnesium at position 1
Site [info] magnesium at position 3
Site [info] magnesium at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 128 sequences 

IPYR1_ARATH (Q93V56), IPYR1_CHLRE (Q93Y52), IPYR1_PSESM (Q889M7), 

IPYR2_ARATH (P21216), IPYR2_CHLRE (Q949J1), IPYR2_HUMAN (Q9H2U2), 
IPYR2_MOUSE (Q91VM9), IPYR2_PSESM (Q87WD6), IPYR2_SCHPO (P87118), 
IPYR2_YEAST (P28239), IPYR3_ARATH (O82793), IPYR4_ARATH (Q9LFF9), 
IPYR5_ARATH (O82597), IPYR6_ARATH (Q9LXC9), IPYR_AERPE  (Q9YBA5), 
IPYR_AGRFC  (Q8UC37), IPYR_AQUAE  (O67501), IPYR_AQUPY  (Q8GQS5), 
IPYR_BACP3  (P19514), IPYR_BARBK  (P51064), IPYR_BOVIN  (P37980), 
IPYR_BRUME  (P65744), IPYR_BRUSU  (P65745), IPYR_BUCAI  (P57190), 
IPYR_BUCAP  (Q8KA31), IPYR_BUCBP  (P59417), IPYR_CAEEL  (Q18680), 
IPYR_CAMJE  (Q9PHM9), IPYR_CANAL  (P83777), IPYR_CANGA  (Q6FRB7), 
IPYR_CHLCV  (Q821T4), IPYR_CHLMU  (Q9PLF1), IPYR_CHLT2  (B0B8Z8), 
IPYR_CHLTA  (Q3KKS0), IPYR_CHLTB  (B0BAM7), IPYR_CHLTR  (O84777), 
IPYR_COREF  (Q8FMF8), IPYR_CORGL  (Q8NM79), IPYR_DEBHA  (Q6BWA5), 
IPYR_DICDI  (Q54PV8), IPYR_DROME  (O77460), IPYR_ECO57  (P0A7B0), 
IPYR_ECOL6  (Q8FAG0), IPYR_ECOLI  (P0A7A9), IPYR_EMENI  (Q5B912), 
IPYR_ENCCU  (Q8SR69), IPYR_EREGS  (Q757J8), IPYR_GEOSE  (O05724), 
IPYR_HAEDU  (Q7VPC0), IPYR_HAEIN  (P44529), IPYR_HALH5  (Q9KCG7), 
IPYR_HALSA  (Q9HSF3), IPYR_HELPJ  (Q9ZLL5), IPYR_HELPY  (P56153), 
IPYR_HORVV  (O23979), IPYR_HUMAN  (Q15181), IPYR_KLULA  (P13998), 
IPYR_LEGPN  (O34955), IPYR_LEIXX  (Q6ACP7), IPYR_MACFA  (Q4R543), 
IPYR_MAIZE  (O48556), IPYR_MALP2  (Q8EVW9), IPYR_METAC  (Q8TMI3), 
IPYR_METKA  (Q8TVE2), IPYR_METMA  (Q8PWY5), IPYR_METTH  (O26363), 
IPYR_MOUSE  (Q9D819), IPYR_MYCBO  (P65747), IPYR_MYCGE  (P47593), 
IPYR_MYCLE  (O69540), IPYR_MYCPN  (P75250), IPYR_MYCPU  (Q98Q96), 
IPYR_MYCTO  (P9WI54), IPYR_MYCTU  (P9WI55), IPYR_NANEQ  (Q74MY6), 
IPYR_NEIMA  (Q9JVG3), IPYR_NEIMB  (Q9K0G4), IPYR_NEUCR  (Q6MVH7), 
IPYR_NOSS1  (P80562), IPYR_ORYSI  (A2X8Q3), IPYR_ORYSJ  (Q0DYB1), 
IPYR_PASMU  (P57918), IPYR_PICPA  (O13505), IPYR_PICTO  (Q6KZB3), 
IPYR_PLAF7  (O77392), IPYR_PONAB  (Q5R8T6), IPYR_PSEAE  (Q9HWZ6), 
IPYR_PSEAO  (P58733), IPYR_PSEPK  (Q88QF6), IPYR_PYRAB  (Q9UY24), 
IPYR_PYRFU  (Q8U438), IPYR_PYRHO  (O59570), IPYR_RALN1  (Q8XWX1), 
IPYR_RHILO  (Q98ER2), IPYR_RHIME  (Q92LH1), IPYR_RHORT  (Q9RGQ1), 
IPYR_RICBR  (Q1RIN6), IPYR_RICCN  (Q92H74), IPYR_RICFE  (Q4UKW0), 
IPYR_RICPR  (Q9ZCW5), IPYR_RICTY  (Q68WE9), IPYR_SACS2  (Q97W51), 
IPYR_SALTI  (P65749), IPYR_SALTY  (P65748), IPYR_SCHPO  (P19117), 
IPYR_SOLTU  (Q43187), IPYR_STRCO  (Q9X8I9), IPYR_SULAC  (P50308), 
IPYR_SULTO  (Q974Y8), IPYR_SYNY3  (P80507), IPYR_THEAC  (P37981), 
IPYR_THEKO  (Q5JIY3), IPYR_THELN  (P77992), IPYR_THET8  (P38576), 
IPYR_THEVB  (Q8DHR2), IPYR_THEVO  (Q979E6), IPYR_UREPA  (Q9PQH6), 
IPYR_VIBCH  (Q9KP34), IPYR_VIBPA  (Q87SW1), IPYR_VIBVU  (Q8DE89), 
IPYR_VIBVY  (Q7MPD2), IPYR_WIGBR  (Q8D274), IPYR_XYLFA  (P65750), 
IPYR_XYLFT  (P65751), IPYR_YARLI  (Q6C1T4), IPYR_YEAST  (P00817), 
IPYR_YERPE  (Q8ZB98), IPYR_ZYGBA  (Q9C0T9)
» more

UniProtKB/Swiss-Prot
False negative sequences		 8 sequences 

IPYR_BRADU  (Q89WY0), IPYR_CAUVC  (Q9AC20), IPYR_CHLPN  (Q9Z6Y8), 

IPYR_GLUOX  (O05545), IPYR_LEPIC  (Q72MG4), IPYR_LEPIN  (Q8EZ21), 
IPYR_XANAC  (Q8PH18), IPYR_XANCP  (Q8P5M4)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 5 sequences 

IPYR_BLAVI  (P82992), IPYR_CYAPA  (P80887), IPYR_EUGGR  (P81987), 

IPYR_NITV2  (P19371), IPYR_OCHDN  (P81988)
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 1 sequence 

JD1_AMOJI   (K7ZGS2)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			129 sequences
			


			
AER3_AERHY  (Q06305), AER4_AERHY  (Q06303), AER5_AERHY  (Q06306), 

			
AERA_AERHY  (P09167), AFTD_MYCS2  (A0QPD4), AGPA_RHIME  (Q9X4Y1), 
ARCA_HALS3  (B0R9X5), AROC_ACICJ  (A5FY49), ASP36_ARATH (Q4V3D2), 
BBS5_CAEEL  (Q21626), BR11_AMOCU  (E1AWD4), BR11_AMOMA  (E1B240), 
BR12_AMOCU  (E1AWD5), BR12_AMOMA  (E1B241), BR15_AMOCU  (E1B228), 
BRA_AMOLO   (A0SN38), BRB_AMOLO   (A0SN42), BYE1_PICGU  (A5DDB7), 
C42_NPVOP   (P24653), CBAB_COMTE  (Q44257), CPL3_ARATH  (Q8LL04), 
CSM3_ASPFU  (A4DA84), CSM3_NEOFI  (A1D9E6), CSM3_NEUCR  (Q7SHE8), 
CYAD_DICDI  (Q55F68), DCN1_YARLI  (Q6C0B6), DIG1_CAEEL  (Q09165), 
DNAJ_BORBU  (P28616), DNAJ_BORGP  (Q661A4), DRE2_LACTC  (C5DJL0), 
END4_GEOSL  (Q74FS7), ENT5_YEAST  (Q03769), FAU1_HALMA  (Q5V0I9), 
FAU1_NATPD  (Q3ITR7), FBD14_ARATH (Q9FNI9), FIBER_BPT1  (Q6XQB2), 
FRMD3_HUMAN (A2A2Y4), FRMD3_PONAB (Q5R803), GDIR2_BOVIN (Q9TU03), 
GLK_BRUA1   (B2SC34), GLK_BRUA2   (Q2YJN9), GLK_BRUAB   (P0CB37), 
GLK_BRUME   (Q8YDC6), GLK_BRUSU   (Q8FV09), GLMM_SALAI  (A8M4B8), 
GLMM_SALTO  (A4XBI5), GSH1_VIBCH  (Q9KUG5), GYP7_DEBHA  (Q6BU76), 
HAP1_YEAS1  (B3RHD9), HAP1_YEAS2  (C7GQY3), HAP1_YEAS7  (A7A1D7), 
HAP1_YEAS8  (C8ZDL9), HAP1_YEASK  (G2WJ80), HAP1_YEAST  (P0CE41), 
HAP1_YEASX  (P0CS82), HETM_NOSS1  (P37693), J1MT1_AMOMA (E1B245), 
JIP5_ASPFU  (Q4WNA1), KCMB3_HUMAN (Q9NPA1), KN12C_ORYSJ (Q5W6L9), 
LCSA_PURLI  (A0A179H164), MAK5_AJECN  (A6R9U4), MAP22_ASPTN (Q0CL94), 
MCA1_SCHPO  (O74477), MCL1A_DANRE (Q9PSI9), MCM9_XENTR  (F6RIX4), 
MNMA_NOCSJ  (A1SMB0), MTGA_PSEF5  (Q4K4C2), MYLKE_DICDI (Q54PB4), 
NAV1_HUMAN  (Q8NEY1), NAV1_MOUSE  (Q8CH77), NHAA1_RHOJR (Q0SG15), 
NPR3_DEBHA  (Q6BQU8), OBG_MYCGA   (Q7NB30), OPF15_ARATH (Q9SJ45), 
OTSA_MYCSK  (A1UM30), OTSA_MYCSS  (Q1B321), PA24A_HORSE (O77793), 
PA24A_HUMAN (P47712), PA24A_PONAB (Q5R8A5), PA24A_RABIT (Q9TT38), 
PA24A_RAT   (P50393), PFMAD_PESFW (W3X7K0), PPN1_NEUCR  (Q9P3S1), 
PRMA_ACIAD  (Q6F9P9), PSF2_PHANO  (Q0UTE1), PUX8_ARATH  (F4JPR7), 
RIBA1_ORYSJ (Q6Z234), RIMO_BACFN  (Q5LCF8), RIMO_BACFR  (Q64TK5), 
RPN8_YEAST  (Q08723), RPOB_ALKMQ  (A6TWJ0), RPOC_ANADE  (Q2II85), 
RPOC_ANADF  (A7HCH6), RPOC_ANASK  (B4UDT1), SKL1_ARATH  (Q9LW20), 
SUMO1_ARATH (P55852), SUMO1_ORYSJ (P55857), SUMO2_ARATH (Q9FLP6), 
SUMO4_ARATH (Q9FKC5), SUMO7_ARATH (Q3E8A8), T2EA_YEAST  (P36100), 
TRA4_CAEEL  (Q20709), TREA_CANAX  (P52494), TUBE2_BPT7  (P03747), 
ULAC_ECO57  (P69821), ULAC_ECOL6  (Q8FAJ0), ULAC_ECOLI  (P69820), 
ULAC_SALCH  (Q57GJ7), ULAC_SALPA  (Q5PJ64), ULAC_SALTI  (Q8Z170), 
ULAC_SALTY  (Q8ZK88), ULAC_SHIBS  (Q31TC6), ULAC_SHIDS  (Q328K2), 
ULAC_SHIFL  (Q83P28), ULAC_SHISS  (Q3YUF3), UTP10_USTMA (Q4P937), 
WASC2_MOUSE (Q6PGL7), XRN2_USTMA  (Q4P149), Y495_SALRD  (Q2S591), 
YCEI_ECO57  (P0A8X3), YCEI_ECOL6  (Q8CW58), YCEI_ECOLI  (P0A8X2), 
YCEI_SHIBS  (Q31ZB2), YCEI_SHIFL  (Q83LI9), YCEI_SHISS  (Q3Z360), 
YCF2_CHLSC  (A6MMG6), YP93_CAEEL  (Q09475), YTZ4_AGRVI  (P70796)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			59 PDB
			


			1E6A; 1E9G; 1FAJ; 1HUJ; 1HUK; 1I40; 1I6T; 1IGP; 1INO; 1IPW; 1JFD; 1M38; 
			
				1MJW; 1MJZ; 1OBW; 1QEZ; 1SXV; 1TWL; 1UDE; 1WCF; 1WGI; 1WGJ; 1YGZ; 1YPP; 
				2AU6; 2AU7; 2AU8; 2AU9; 2AUU; 2BQX; 2BQY; 2EIP; 2IHP; 2IK0; 2IK1; 2IK9; 
				2PRD; 2UXS; 3D53; 3EMJ; 4ECP; 4LUG; 4UM4; 4XEL; 4Z70; 4Z71; 4Z72; 4Z73; 
				4Z74; 5KDE; 5KDF; 5LS0; 5TEA; 5WRU; 6C45; 6WE5; 7BTN; 7CMO; 8PRK
			
			

			» more