PROSITE entry PS00417

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00417
Entry name [info]	SYNAPTOBREVIN
Accession [info]	PS00417
Entry type [info]	PATTERN
Date [info]	01-NOV-1990 CREATED; 01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00368

Name and characterization of the entry

Description [info]	Synaptobrevin signature.
Pattern [info]	[NT]-[LIVMF]-[DENSTG]-[KLNRGS]-[VAI]-x-[DEQA]-R-x(2)-[KRN]-[LIVM]- [STDEA]-x-[LIVM]-x-[DEQGN]-[KR]-[TAS]-[DEAS].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	62 in 62 different sequences
Number of true positive hits	62 in 62 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	22
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	73.81 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Version [info]	2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

62 sequences

NSYB_DROME  (Q9W0C1), SNC1_YEAST  (P31109), SNC2_YEAST  (P33328),

SYB1_CAEBR  (Q60WU2), SYB1_CAEEL  (O02495), SYB1_SCHPO  (Q92356), 
SYBL_SCHMA  (Q27236), SYB_APLCA   (P35589), SYB_DORPE   (P47194), 
SYB_DROME   (P18489), SYB_TETCF   (P13701), VA711_ARATH (O49377), 
VA712_ARATH (Q9SIQ9), VA713_ARATH (Q9LFP1), VA714_ARATH (Q9FMR5), 
VA721_ARATH (Q9ZTW3), VA722_ARATH (P47192), VA724_ARATH (O23429), 
VA725_ARATH (O48850), VA726_ARATH (Q9MAS5), VA727_ARATH (Q9M376), 
VAMP1_BOVIN (Q0V7N0), VAMP1_HUMAN (P23763), VAMP1_MOUSE (Q62442), 
VAMP1_RAT   (Q63666), VAMP2_BOVIN (P63026), VAMP2_HUMAN (P63027), 
VAMP2_MACMU (Q9N0Y0), VAMP2_MOUSE (P63044), VAMP2_RAT   (P63045), 
VAMP2_XENLA (P47193), VAMP3_BOVIN (Q2KJD2), VAMP3_HUMAN (Q15836), 
VAMP3_MACFA (Q4R8T0), VAMP3_MOUSE (P63024), VAMP3_RAT   (P63025), 
VAMP4_BOVIN (Q32L97), VAMP4_HUMAN (O75379), VAMP4_MOUSE (O70480), 
VAMP5_BOVIN (Q2KHY2), VAMP5_HUMAN (O95183), VAMP5_MOUSE (Q9Z2P8), 
VAMP5_RAT   (Q9Z2J5), VAMP7_BOVIN (Q17QI5), VAMP7_CHICK (Q5ZL74), 
VAMP7_HUMAN (P51809), VAMP7_MOUSE (P70280), VAMP7_PONAB (Q5RF94), 
VAMP7_RAT   (Q9JHW5), VAMP8_BOVIN (Q3T0Y8), VAMP8_HUMAN (Q9BV40), 
VAMP8_PONAB (Q5REQ5), VAMP8_RAT   (Q9WUF4), YKT61_ARATH (Q9ZRD6), 
YKT62_ARATH (Q9LVM9), YKT6_CANGA  (Q6FW27), YKT6_DEBHA  (Q6BSL0), 
YKT6_EREGS  (Q757A4), YKT6_KLULA  (Q6CSA2), YKT6_SCHPO  (O60073), 
YKT6_YARLI  (Q6C537), YKT6_YEAST  (P36015)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

22 sequences

SC221_ARATH (Q94AU2), SEC22_CANGA (Q6FWT0), SEC22_EREGS (Q74ZD2),

SEC22_KLULA (Q6CJA0), SEC22_SCHPO (Q9Y7L0), SEC22_YARLI (Q6C880), 
SEC22_YEAST (P22214), SYBA_DICDI  (Q6TMJ9), SYBB_DICDI  (Q54GB3), 
VA723_ARATH (Q8VY69), VAM7A_DICDI (Q54NW7), VAM7B_DICDI (Q86AQ7), 
VAMP8_MOUSE (O70404), YKT6A_XENLA (Q6DDU7), YKT6B_XENLA (Q32N70), 
YKT6_BOVIN  (Q3T000), YKT6_DANRE  (Q7ZUN8), YKT6_DICDI  (Q54ES8), 
YKT6_HUMAN  (O15498), YKT6_MOUSE  (Q9CQW1), YKT6_RAT(Q5EGY4), 
YKT6_XENTR  (Q6P816)

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PDB
[Detailed view]

30 PDB

1GL2; 1KIL; 1L4A; 1N7S; 1SFC; 2KOG; 2N1T; 2NPS; 3B5N; 3HD7; 3IPD; 3J96; 3J97; 3J98; 3J99; 4B93; 4WY4; 5CCG; 5CCH; 5CCI; 5KJ7; 5KJ8; 6IP1; 6MDM; 6MDN; 6MTI; 6WVW; 7BV6; 7UDB; 7UDC
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