PROSITE entry PS00422

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PURL: https://purl.expasy.org/prosite/signature/PS00422

Direct ScanProsite submission

General information about the entry

Entry name [info]	GRANINS_1
Accession [info]	PS00422
Entry type [info]	PATTERN
Date [info]	01-NOV-1990 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00365

Name and characterization of the entry

Description [info]	Granins signature 1.
Pattern [info]	[DE]-[SN]-L-[SAN]-{EGI}-{ELT}-[DE]-x-E-L.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	27 in 27 different sequences
Number of true positive hits	18 in 18 different sequences
Number of 'unknown' hits	0
Number of false positive hits	9 in 9 different sequences
Number of false negative sequences	4
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	66.67 %
Recall (true positives / (true positives + false negatives))	81.82 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

18 sequences

CMGA_BOVIN  (P05059), CMGA_HORSE  (Q9XS63), CMGA_HUMAN  (P10645),

CMGA_MOUSE  (P26339), CMGA_PIG(P04404), CMGA_RAT(P10354), 
CMGA_STRCA  (P33716), SCG1_BOVIN  (P23389), SCG1_HUMAN  (P05060), 
SCG1_MOUSE  (P16014), SCG1_PIG(Q9GLG4), SCG1_RAT(O35314), 
SCG2_BOVIN  (P20616), SCG2_HUMAN  (P13521), SCG2_MACFA  (Q4R5E9), 
SCG2_PIG(Q5FZP5), SCG2_PONAB  (Q5R4M6), SCG2_RAT(P10362)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

4 sequences

SCG2A_DANRE (C0HM54), SCG2B_DANRE (A0JMK6), SCG2_MOUSE  (Q03517),

SCG2_PELRI  (P30945)

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UniProtKB/Swiss-Prot
False positive sequences

9 sequences

CPRC2_CANPA (Q76L36), EVI5L_HUMAN (Q96CN4), GLYA_CERS4  (Q3IZN2),

M3K7_DROME  (Q9V3Q6), PPR29_MOUSE (Q68FM6), RHGF_DROME  (X2JDY8), 
RNY_DESAP   (B1I3H5), TWIST_XENLA (P13903), Y534_METFV  (P56509)

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