PROSITE entry PS00424

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00424
Entry name [info]	INTERLEUKIN_2
Accession [info]	PS00424
Entry type [info]	PATTERN
Date [info]	01-NOV-1990 CREATED; 01-MAY-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00349

Name and characterization of the entry

Description [info]	Interleukin-2 signature.
Pattern [info]	T-E-[LF]-x(2)-L-x-C-L-x(2)-E-L.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	39 in 39 different sequences
Number of true positive hits	39 in 39 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Site [info]	disulfide at position 7
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

39 sequences

IL2_AILME   (Q5PXD0), IL2_AOTLE   (Q7JFM2), IL2_AOTNA   (Q7JFM5),

IL2_AOTNI   (Q7JFM3), IL2_AOTVO   (Q7JFM4), IL2_BOSTR   (Q4U313), 
IL2_BOVIN   (P05016), IL2_BUBBU   (Q95KP3), IL2_BUBCA   (Q2PE78), 
IL2_CAMBA   (Q2PE47), IL2_CANLF   (Q29416), IL2_CAPHI   (P36835), 
IL2_CERAT   (P46649), IL2_CEREL   (P51747), IL2_DASNO   (Q1WM29), 
IL2_DELLE   (Q9XT84), IL2_FELCA   (Q07885), IL2_HALGR   (Q9XT83), 
IL2_HORSE   (P37997), IL2_HUMAN   (P60568), IL2_HYLLA   (P60569), 
IL2_LAMGL   (Q865X2), IL2_MACFA   (Q29615), IL2_MACMU   (P68291), 
IL2_MACNE   (P68290), IL2_MERUN   (Q08081), IL2_MIRAN   (O62641), 
IL2_MOSBE   (Q5MBA8), IL2_MOUSE   (P04351), IL2_MUSSP   (Q08867), 
IL2_ORCOR   (O97513), IL2_PAPAN   (Q865Y1), IL2_PAPHA   (Q9XS38), 
IL2_PIG (P26891), IL2_RABIT   (O77620), IL2_RAT (P17108), 
IL2_SAISC   (Q8MKH2), IL2_SHEEP   (P19114), IL2_VULVU   (Q25BC3)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
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PDB
[Detailed view]

32 PDB

1IRL; 1M47; 1M48; 1M49; 1M4A; 1M4B; 1M4C; 1NBP; 1PW6; 1PY2; 1QVN; 1Z92; 2B5I; 2ERJ; 3INK; 3QAZ; 3QB1; 4NEJ; 4NEM; 4YQX; 4YUE; 5LQB; 5M5E; 5UTZ; 6VWU; 6YE3; 7DR4; 7M2G; 7RAA; 7ZMZ; 8SOW; 8SOZ
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