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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
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Amos Bairoch

PROSITE entry PS00424


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PURL: https://purl.expasy.org/prosite/signature/PS00424

Direct ScanProsite submission
General information about the entry

Entry name [info] INTERLEUKIN_2
Accession [info] PS00424
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-MAY-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00349

Name and characterization of the entry

Description [info] Interleukin-2 signature.
Pattern [info]
T-E-[LF]-x(2)-L-x-C-L-x(2)-E-L.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 39 in 39 different sequences
Number of true positive hits 39 in 39 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
39 sequences

IL2_AILME   (Q5PXD0), IL2_AOTLE   (Q7JFM2), IL2_AOTNA   (Q7JFM5), 
IL2_AOTNI   (Q7JFM3), IL2_AOTVO   (Q7JFM4), IL2_BOSTR   (Q4U313), 
IL2_BOVIN   (P05016), IL2_BUBBU   (Q95KP3), IL2_BUBCA   (Q2PE78), 
IL2_CAMBA   (Q2PE47), IL2_CANLF   (Q29416), IL2_CAPHI   (P36835), 
IL2_CERAT   (P46649), IL2_CEREL   (P51747), IL2_DASNO   (Q1WM29), 
IL2_DELLE   (Q9XT84), IL2_FELCA   (Q07885), IL2_HALGR   (Q9XT83), 
IL2_HORSE   (P37997), IL2_HUMAN   (P60568), IL2_HYLLA   (P60569), 
IL2_LAMGL   (Q865X2), IL2_MACFA   (Q29615), IL2_MACMU   (P68291), 
IL2_MACNE   (P68290), IL2_MERUN   (Q08081), IL2_MIRAN   (O62641), 
IL2_MOSBE   (Q5MBA8), IL2_MOUSE   (P04351), IL2_MUSSP   (Q08867), 
IL2_ORCOR   (O97513), IL2_PAPAN   (Q865Y1), IL2_PAPHA   (Q9XS38), 
IL2_PIG (P26891), IL2_RABIT   (O77620), IL2_RAT (P17108), 
IL2_SAISC   (Q8MKH2), IL2_SHEEP   (P19114), IL2_VULVU   (Q25BC3)
» more

PDB
[Detailed view]
32 PDB

pdb_00001irl; pdb_00001m47; pdb_00001m48; pdb_00001m49; pdb_00001m4a; pdb_00001m4b; pdb_00001m4c; pdb_00001nbp; pdb_00001pw6; pdb_00001py2; pdb_00001qvn; pdb_00001z92; pdb_00002b5i; pdb_00002erj; pdb_00003ink; pdb_00003qaz; pdb_00003qb1; pdb_00004nej; pdb_00004nem; pdb_00004yqx; pdb_00004yue; pdb_00005lqb; pdb_00005m5e; pdb_00005utz; pdb_00006vwu; pdb_00006ye3; pdb_00007dr4; pdb_00007m2g; pdb_00007raa; pdb_00007zmz; pdb_00008sow; pdb_00008soz
» more