PROSITE logo

PROSITE entry PS00433


View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] PHOSPHOFRUCTOKINASE
Accession [info] PS00433
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-APR-2006 DATA UPDATE;
03-MAY-2023 INFO UPDATE.
PROSITE Doc. [info] PDOC00336

Name and characterization of the entry

Description [info] Phosphofructokinase signature.
Pattern [info] 
[RK]-x(4)-[GAS]-H-x-[QL]-[QR]-[GS]-[GF]-x(5)-[DE]-[RL].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2023_02 which contains 569'516 sequence entries.


Total number of hits 340 in 303 different sequences
Number of true positive hits 340 in 303 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 16
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 95.51 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] substrate_binding at position 1
Site [info] substrate_binding at position 4
Site [info] substrate_binding at position 7
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 303 sequences 

PFKA1_ASPOR (Q9HGZ1    ), PFKA1_BACTN (Q8A8R5    ), PFKA1_CAEEL (Q9TZL8    ), 

PFKA1_CANAX (O94201    ), PFKA1_KLULA (Q03215    ), PFKA1_KOMPG (Q92448    ), 
PFKA1_LACLL (P0DOB6    ), PFKA1_NOSS1 (Q8YKG3    ), PFKA1_PICPA (Q8NJU8    ), 
PFKA1_SYNY3 (P72830    ), PFKA1_THET8 (P21777    ), PFKA1_YEAST (P16861    ), 
PFKA2_ASPOR (Q9HGZ0    ), PFKA2_BACTN (Q8A624    ), PFKA2_CAEEL (Q27483    ), 
PFKA2_CANAX (O94200    ), PFKA2_CLOPE (Q8XL57    ), PFKA2_KLULA (Q03216    ), 
PFKA2_KOMPG (C4QXA5    ), PFKA2_LACLL (P0DOB7    ), PFKA2_NOSS1 (Q8YVR1    ), 
PFKA2_PICPA (Q8TGA0    ), PFKA2_STRCO (Q9L1L8    ), PFKA2_SYNY3 (Q55988    ), 
PFKA2_YEAST (P16862    ), PFKA3_STRCO (Q9FC99    ), PFKAL_BOVIN (A1A4J1    ), 
PFKAL_HUMAN (P17858    ), PFKAL_MOUSE (P12382    ), PFKAL_PONAB (Q5R7V5    ), 
PFKAL_RAT   (P30835    ), PFKAM_BOVIN (Q0IIG5    ), PFKAM_CANLF (P52784    ), 
PFKAM_HORSE (Q867C9    ), PFKAM_HUMAN (P08237    ), PFKAM_MACFA (Q60HD9    ), 
PFKAM_MOUSE (P47857    ), PFKAM_PIG   (Q2HYU2    ), PFKAM_PONAB (Q5RAG9    ), 
PFKAM_RABIT (P00511    ), PFKAM_RAT   (P47858    ), PFKAP_HUMAN (Q01813    ), 
PFKAP_MOUSE (Q9WUA3    ), PFKAP_PONAB (Q5R636    ), PFKAP_RABIT (P47859    ), 
PFKAP_RAT   (P47860    ), PFKA_ACTP2  (A3N1C8    ), PFKA_ACTP7  (B3GY11    ), 
PFKA_ACTPJ  (B0BQ64    ), PFKA_ACTSZ  (A6VM63    ), PFKA_ALIF1  (Q5E2B1    ), 
PFKA_ALIFM  (B5FBT1    ), PFKA_ALISL  (B6EMS4    ), PFKA_ALKCK  (Q5WEF6    ), 
PFKA_ALKMQ  (A6TVD3    ), PFKA_ALKOO  (A8MLY0    ), PFKA_ANOFW  (B7GGT1    ), 
PFKA_AQUAE  (O67605    ), PFKA_ASPFU  (Q4W9B8    ), PFKA_ASPNG  (P78985    ), 
PFKA_BACAA  (C3PAI8    ), PFKA_BACAC  (C3L8X8    ), PFKA_BACAH  (A0RJJ6    ), 
PFKA_BACAN  (Q81KZ0    ), PFKA_BACC0  (B7JRX2    ), PFKA_BACC1  (Q72ZD8    ), 
PFKA_BACC2  (B7IJZ8    ), PFKA_BACC3  (C1EUU3    ), PFKA_BACC4  (B7HFB3    ), 
PFKA_BACC7  (B7HRN9    ), PFKA_BACCE  (Q4MVY3    ), PFKA_BACCN  (A7GTP4    ), 
PFKA_BACCQ  (B9J099    ), PFKA_BACCR  (Q817F3    ), PFKA_BACCZ  (Q633J8    ), 
PFKA_BACHK  (Q6HCT3    ), PFKA_BACLD  (Q65G82    ), PFKA_BACMK  (A9VJR1    ), 
PFKA_BACP2  (A8FG55    ), PFKA_BACSU  (O34529    ), PFKA_BACVZ  (A7Z7K6    ), 
PFKA_BAUCH  (Q1LTT2    ), PFKA_BLOFL  (Q7VRK9    ), PFKA_BREBN  (C0Z7W7    ), 
PFKA_BUCA5  (B8D996    ), PFKA_BUCAI  (P57391    ), PFKA_BUCAP  (Q8K9N0    ), 
PFKA_BUCAT  (B8D7J8    ), PFKA_BUCBP  (P59563    ), PFKA_BUCCC  (Q057P0    ), 
PFKA_CALS4  (Q8R914    ), PFKA_CHLAA  (A9WCU2    ), PFKA_CHLAD  (B8GAA4    ), 
PFKA_CHLSY  (B9LHK4    ), PFKA_CITK8  (A8AL13    ), PFKA_CLOAB  (O08308    ), 
PFKA_CLOB1  (A7FYW7    ), PFKA_CLOB6  (C3KV06    ), PFKA_CLOBA  (B2UZX8    ), 
PFKA_CLOBB  (B2TQR6    ), PFKA_CLOBH  (A5I798    ), PFKA_CLOBJ  (C1FM55    ), 
PFKA_CLOBK  (B1IFV9    ), PFKA_CLOBL  (A7GIW9    ), PFKA_CLOBM  (B1L266    ), 
PFKA_CLOD6  (Q180P4    ), PFKA_CLONN  (A0PYC8    ), PFKA_CLOTE  (Q890Z2    ), 
PFKA_COREF  (Q8RQN5    ), PFKA_CORGL  (Q8NR14    ), PFKA_COXBU  (Q83EH9    ), 
PFKA_CROS8  (A7MQ83    ), PFKA_CYTH3  (Q11RE2    ), PFKA_DEIRA  (Q9RWN1    ), 
PFKA_DICDI  (P90521    ), PFKA_DROME  (P52034    ), PFKA_ECO24  (A7ZUC9    ), 
PFKA_ECO27  (B7UNN6    ), PFKA_ECO45  (B7MI48    ), PFKA_ECO55  (B7LA13    ), 
PFKA_ECO57  (P0A797    ), PFKA_ECO5E  (B5YZ53    ), PFKA_ECO7I  (B7NU91    ), 
PFKA_ECO81  (B7N2Q7    ), PFKA_ECO8A  (B7M6W7    ), PFKA_ECOBW  (C5A083    ), 
PFKA_ECODH  (B1XB82    ), PFKA_ECOHS  (A8A720    ), PFKA_ECOL5  (Q0TAE8    ), 
PFKA_ECOL6  (Q8FBD0    ), PFKA_ECOLC  (B1IVG3    ), PFKA_ECOLI  (P0A796    ), 
PFKA_ECOLU  (B7NFL3    ), PFKA_ECOSE  (B6I4Q8    ), PFKA_ECOSM  (B1LNL9    ), 
PFKA_EDWI9  (C5BC26    ), PFKA_ENT38  (A4WG81    ), PFKA_ENTCL  (Q9Z6C3    ), 
PFKA_ERWT9  (B2VF62    ), PFKA_ESCF3  (B7LVC9    ), PFKA_FINM2  (B0S230    ), 
PFKA_FUSNN  (Q8RG98    ), PFKA_GEOKA  (Q5KWB1    ), PFKA_GEOSE  (P00512    ), 
PFKA_GEOSW  (C5D663    ), PFKA_GLAP5  (B8F8G9    ), PFKA_HAECO  (Q27665    ), 
PFKA_HAEDU  (Q8GNC1    ), PFKA_HAEI8  (Q4QLS8    ), PFKA_HAEIE  (A5UD89    ), 
PFKA_HAEIN  (P43863    ), PFKA_HAES1  (Q0I267    ), PFKA_HALH5  (Q9K843    ), 
PFKA_HALOH  (B8D1K5    ), PFKA_HAMD5  (C4K7E1    ), PFKA_HISS2  (B0UW05    ), 
PFKA_KLEP3  (B5XZ40    ), PFKA_KLEP7  (A6TGB8    ), PFKA_LACAC  (Q5FKG6    ), 
PFKA_LACDE  (P80019    ), PFKA_LACGA  (Q043V2    ), PFKA_LACH4  (A8YV22    ), 
PFKA_LACJO  (Q74JM8    ), PFKA_LACLA  (P0DOB5    ), PFKA_LACLM  (A2RKA2    ), 
PFKA_LACLS  (Q02YK5    ), PFKA_LACPL  (Q88VY1    ), PFKA_LIGS1  (Q1WTT3    ), 
PFKA_LISIN  (Q92BE4    ), PFKA_LISMC  (C1KVL8    ), PFKA_LISMF  (Q71Z96    ), 
PFKA_LISMH  (B8DHH7    ), PFKA_LISMO  (Q8Y6W0    ), PFKA_LISW6  (A0AJ20    ), 
PFKA_LYSSH  (Q93LR4    ), PFKA_MACCJ  (B9E7A4    ), PFKA_MANSM  (Q65VM6    ), 
PFKA_MESH2  (Q601D3    ), PFKA_MESH7  (Q4A8Q3    ), PFKA_MESHJ  (Q4AAM2    ), 
PFKA_MESM1  (Q6KHX0    ), PFKA_MYCBO  (P65691    ), PFKA_MYCCT  (Q2SSQ6    ), 
PFKA_MYCLE  (O33106    ), PFKA_MYCPU  (Q98PW8    ), PFKA_MYCTO  (P9WID6    ), 
PFKA_MYCTU  (P9WID7    ), PFKA_NATTJ  (B2A6Y0    ), PFKA_OCEIH  (Q8EPD6    ), 
PFKA_PAEMC  (Q59214    ), PFKA_PASMU  (Q9CPH2    ), PFKA_PECAS  (Q6CZ46    ), 
PFKA_PECCP  (C6DHK2    ), PFKA_PEDPA  (Q03F74    ), PFKA_PHOPR  (Q6LVK2    ), 
PFKA_SALA4  (B5F0P6    ), PFKA_SALAR  (A9MI50    ), PFKA_SALCH  (Q57HF3    ), 
PFKA_SALDC  (B5FPR2    ), PFKA_SALEP  (B5QWZ5    ), PFKA_SALG2  (B5RFA9    ), 
PFKA_SALHS  (B4TCK0    ), PFKA_SALNS  (B4T049    ), PFKA_SALPA  (Q5PIR6    ), 
PFKA_SALPB  (A9MZE7    ), PFKA_SALPC  (C0Q414    ), PFKA_SALPK  (B5BJI2    ), 
PFKA_SALSV  (B4TPS6    ), PFKA_SALTI  (P65693    ), PFKA_SALTY  (P65692    ), 
PFKA_SCHMA  (Q27778    ), PFKA_SCHPO  (O42938    ), PFKA_SERP5  (A8GLB0    ), 
PFKA_SHIB3  (B2TVQ8    ), PFKA_SHIBS  (Q31U74    ), PFKA_SHIDS  (Q32A80    ), 
PFKA_SHIFL  (P0A798    ), PFKA_SHISS  (Q3YV62    ), PFKA_SODGM  (Q2NQX2    ), 
PFKA_SPICI  (P20275    ), PFKA_STAA2  (A6U2G5    ), PFKA_STAA8  (Q2FXM8    ), 
PFKA_STAA9  (A5ITM2    ), PFKA_STAAB  (Q2YTE2    ), PFKA_STAAC  (Q5HF75    ), 
PFKA_STAAE  (A6QHN3    ), PFKA_STAAM  (P65694    ), PFKA_STAAN  (P99165    ), 
PFKA_STAAR  (Q6GG08    ), PFKA_STAAS  (Q6G8M8    ), PFKA_STAAT  (A8Z2L4    ), 
PFKA_STAAW  (P65695    ), PFKA_STACT  (B9DN94    ), PFKA_STAEQ  (Q5HNK6    ), 
PFKA_STAES  (Q8CS68    ), PFKA_STRA1  (Q3K1E6    ), PFKA_STRA3  (P65696    ), 
PFKA_STRA5  (P65697    ), PFKA_STRE4  (C0M8V6    ), PFKA_STREM  (B4U2M2    ), 
PFKA_STRGC  (A8AXW1    ), PFKA_STRMU  (Q8DTX6    ), PFKA_STRP1  (Q99ZD0    ), 
PFKA_STRP2  (Q04L24    ), PFKA_STRP3  (P0DD02    ), PFKA_STRP4  (B5E3Z8    ), 
PFKA_STRP6  (Q5XBV2    ), PFKA_STRP7  (C1C6M8    ), PFKA_STRP8  (Q8P0S6    ), 
PFKA_STRPB  (Q1JBF7    ), PFKA_STRPC  (Q1JLD9    ), PFKA_STRPD  (Q1JGH6    ), 
PFKA_STRPF  (Q1J694    ), PFKA_STRPG  (A2RE65    ), PFKA_STRPI  (B1IB66    ), 
PFKA_STRPJ  (B8ZNU0    ), PFKA_STRPM  (Q48T86    ), PFKA_STRPN  (Q97RC6    ), 
PFKA_STRPQ  (P0DD03    ), PFKA_STRPS  (B2IP53    ), PFKA_STRPZ  (B5XLV6    ), 
PFKA_STRR6  (Q8DQ85    ), PFKA_STRS7  (C0MGJ9    ), PFKA_STRSV  (A3CM69    ), 
PFKA_STRSY  (A4VTS0    ), PFKA_STRU0  (B9DSA4    ), PFKA_STRZJ  (C1CDP4    ), 
PFKA_STRZP  (C1CJY4    ), PFKA_STRZT  (C1CRZ7    ), PFKA_SULDN  (Q30T53    ), 
PFKA_SULNB  (A6QAB4    ), PFKA_TERTT  (C5BNR1    ), PFKA_THEMA  (Q9WY52    ), 
PFKA_THENN  (B9K6R9    ), PFKA_THEP1  (A5IKL2    ), PFKA_THEP3  (B0K7U7    ), 
PFKA_THEPX  (B0K6L2    ), PFKA_THESQ  (B1L9U3    ), PFKA_THET2  (Q72H98    ), 
PFKA_THEVB  (Q8DJB1    ), PFKA_TOLAT  (C4LEQ5    ), PFKA_TRIV2  (Q3M8N2    ), 
PFKA_VIBC1  (A7MX59    ), PFKA_VIBCH  (Q9KNP2    ), PFKA_VIBPA  (Q87KX0    ), 
PFKA_VIBVU  (Q8DCY1    ), PFKA_VIBVY  (Q7MGW6    ), PFKA_WOLSU  (Q7M9C2    ), 
PFKA_YARLI  (P59680    ), PFKA_YERE8  (A1JHZ3    ), PFKA_YERP3  (A7FCW1    ), 
PFKA_YERPA  (Q1C297    ), PFKA_YERPB  (B2JZA3    ), PFKA_YERPE  (Q8ZJL6    ), 
PFKA_YERPG  (A9R6A3    ), PFKA_YERPN  (Q1CD33    ), PFKA_YERPP  (A4TSA7    ), 
PFKA_YERPS  (Q66GA8    ), PFKA_YERPY  (B1JQU4    ), PFP_AMYME   (Q59126    ), 
PFP_AMYMS   (Q9AGC0    ), PFP_DICTH   (Q9KH71    ), PFP_STRCO   (O08333    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 16 sequences 

PFKA1_CLOPE (Q8XNH2    ), PFKA3_BACTN (Q8A2E9    ), PFKA_ENTFA  (Q836R3    ), 

PFKA_LACCB  (B3WE64    ), PFKA_LACP3  (Q039I0    ), PFKA_MALP2  (Q8EVH2    ), 
PFKA_MYCGE  (P47457    ), PFKA_MYCPN  (P75476    ), PFKA_PERMH  (C0QQX4    ), 
PFKA_PROFC  (D7GCU5    ), PFKA_SPITD  (E0RTD9    ), PFKA_STRTD  (Q03KB7    ), 
PFKA_STRTR  (Q9L9E3    ), PFKA_SULSY  (B2V7W7    ), PFKA_UREPA  (Q9PQV8    ), 
PFP_THETK   (G4RK16    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

PFKA2_THET8 (P21778    ), PFKA_CALFI  (Q27543    )


				
	

	

		PDB
[Detailed view]		
		
			30 PDB
			


			1MTO; 1PFK; 1ZXX; 2PFK; 3O8L; 3O8N; 3O8O; 3OPY; 3PFK; 3U39; 4A3S; 4I36; 
			
				4I4I; 4I7E; 4OMT; 4PFK; 4RH3; 4U1R; 4WL0; 4XYJ; 4XYK; 4XZ2; 5XOE; 5XZ6; 
				5XZ7; 5XZ8; 5XZ9; 5XZA; 6PFK; 7LW1
			
			

			» more