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PROSITE entry PS00434


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General information about the entry

Entry name [info] HSF_DOMAIN
Accession [info] PS00434
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00381

Name and characterization of the entry

Description [info] HSF-type DNA-binding domain signature.
Pattern [info] 
L-x(3)-[FY]-K-H-x-N-x-[STAN]-S-F-[LIVM]-R-Q-L-[NH]-x-Y-x-[FYW]-[RKH]-K-
[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.


Total number of hits 76 in 76 different sequences
Number of true positive hits 76 in 76 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 11
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 87.36 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 76 sequences 

HFA1A_ARATH (P41151), HFA1B_ARATH (O81821), HFA1D_ARATH (Q9LQM7), 

HFA1E_ARATH (Q9SCW5), HFA2A_ORYSJ (Q84MN7), HFA2B_ORYSJ (Q6VBB2), 
HFA2C_ORYSJ (Q338B0), HFA2D_ORYSJ (Q8H7Y6), HFA2E_ORYSJ (Q6F388), 
HFA4B_ORYSJ (Q94J16), HFA4C_ARATH (Q9FK72), HFA4D_ORYSJ (Q93VB5), 
HFA6A_ARATH (Q1PDN3), HFA6A_ORYSJ (Q5Z6A4), HFA6B_ARATH (Q9LUH8), 
HFA6B_ORYSJ (Q657C0), HFA7A_ARATH (Q9SV12), HFA7B_ARATH (Q9M1V5), 
HFB2A_ARATH (Q9SCW4), HFB2A_ORYSJ (Q7XRX3), HFB2B_ARATH (Q9T0D3), 
HFB2B_ORYSJ (Q6Z9C8), HFB2C_ORYSJ (Q652B0), HFB4A_ORYSJ (Q6Z9R8), 
HFB4B_ORYSJ (Q7XHZ0), HFB4C_ORYSJ (Q67U94), HFB4D_ORYSJ (Q10KX8), 
HFC1A_ORYSJ (Q6VBA4), HFC1B_ORYSJ (Q942D6), HFC2A_ORYSJ (Q6EUG4), 
HFC2B_ORYSJ (Q0DBL6), HSF1_BOVIN  (Q08DJ8), HSF1_CHICK  (P38529), 
HSF1_HUMAN  (Q00613), HSF1_MOUSE  (P38532), HSF24_SOLPE (P22335), 
HSF2_CHICK  (P38530), HSF2_HUMAN  (Q03933), HSF2_MOUSE  (P38533), 
HSF30_SOLPE (P41152), HSF3_CHICK  (P38531), HSF4_CANLF  (Q1HGE8), 
HSF4_DANRE  (Q5CZP2), HSF4_HUMAN  (Q9ULV5), HSF4_MOUSE  (Q9R0L1), 
HSF8_SOLLC  (Q40152), HSF8_SOLPE  (P41153), HSFA1_ORYSJ (Q84T61), 
HSFA2_ARATH (O80982), HSFA3_ARATH (Q8GYY1), HSFA3_ORYSJ (Q6H6Q7), 
HSFA5_ARATH (Q94BZ5), HSFA5_ORYSJ (Q6K6S5), HSFA8_ARATH (Q9S7U5), 
HSFA9_ARATH (Q9LVW2), HSFA9_ORYSJ (Q10PR4), HSFB1_ORYSJ (Q67TP9), 
HSFB3_ARATH (O22230), HSFB4_ARATH (Q9C635), HSFC1_ARATH (Q9LV52), 
HSF_CANAL   (Q5AQ33), HSF_CRYNH   (J9VHZ9), HSF_CRYNJ   (Q5KMX8), 
HSF_DROME   (P22813), HSF_KLULA   (P22121), HSF_SCHPO   (Q02953), 
HSF_XENLA   (P41154), HSF_YEAST   (P10961), MGA1_YEAST  (P53050), 
PRR1_SCHPO  (O14283), SFL1_CANAL  (Q5A287), SFL1_YEAST  (P20134), 
SFL2_CANAL  (Q5AK51), SKN7_CANAL  (Q5A4X5), SKN7_CHATD  (G0SB31), 
SKN7_YEAST  (P38889)
» more

UniProtKB/Swiss-Prot
False negative sequences		 11 sequences 

HFA4A_ARATH (O49403), HMS2_YEAST  (P47175), HSF3_MOUSE  (D0VYS2), 

HSF5_HUMAN  (Q4G112), HSF5_MOUSE  (Q5ND04), HSFB1_ARATH (Q96320), 
HSFX1_HUMAN (Q9UBD0), HSFY1_HUMAN (Q96LI6), HSF_ENCCU   (Q8SS62), 
HSF_ENTBH   (B7XIV9), HSF_VAIC1   (C4V6H6)
» more

PDB
[Detailed view]		 28 PDB

1FBQ; 1FBS; 1FBU; 1FYK; 1FYL; 1FYM; 1HKS; 1HKT; 2HTS; 2LDU; 3HSF; 3HTS; 5D5U; 5D5V; 5D5W; 5D5X; 5D8K; 5D8L; 5HDG; 5HDK; 5HDN; 6J6V; 6J6W; 7DCI; 7DCJ; 7DCS; 7DCT; 7DCU
» more