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PROSITE entry PS00482


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General information about the entry

Entry name [info] DIHYDROOROTASE_1
Accession [info] PS00482
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-JUL-1999 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00401

Name and characterization of the entry

Description [info] Dihydroorotase signature 1.
Pattern [info]
D-[LIVMFYWSAP]-H-[LIVA]-H-[LIVF]-[RN]-x-[PGANF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 297 in 297 different sequences
Number of true positive hits 283 in 283 different sequences
Number of 'unknown' hits 0
Number of false positive hits 14 in 14 different sequences
Number of false negative sequences 64
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 95.29 %
Recall (true positives / (true positives + false negatives)) 81.56 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] zinc(?) at position 3
Site [info] zinc(?) at position 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
283 sequences

ALN1_DICDI  (Q54SV3), ALN2_DICDI  (Q55C91), ALN_AQUCT   (P40757), 
ALN_YEAST   (P32375), PYR1_CAEEL  (Q18990), PYR1_DICDI  (P20054), 
PYR1_DROME  (P05990), PYR1_HUMAN  (P27708), PYR1_MESAU  (P08955), 
PYR1_MOUSE  (B2RQC6), PYR1_SQUAC  (Q91437), PYRC_ACAM1  (B0CF78), 
PYRC_ACIAD  (Q6FD29), PYRC_ACIB3  (B7GX48), PYRC_ACIB5  (B7I9G6), 
PYRC_ACIBC  (B2HWF6), PYRC_ACIBS  (B0VKW9), PYRC_ACIBT  (A3M3K3), 
PYRC_ACIBY  (B0VAC1), PYRC_ACISJ  (A1WC79), PYRC_AGRFC  (Q8UI99), 
PYRC_ALCBS  (Q0VNK6), PYRC_ALIF1  (Q5E0G4), PYRC_ALIFM  (B5ETI9), 
PYRC_ALISL  (B6ER91), PYRC_ALKEH  (Q0AB36), PYRC_ALLAM  (B9JQV9), 
PYRC_ANAD2  (B8JAE8), PYRC_ANADE  (Q2IIB0), PYRC_ANAPZ  (Q2GL89), 
PYRC_ANASK  (B4UDQ2), PYRC_ANOFW  (B7GFA5), PYRC_AQUAE  (O66990), 
PYRC_ARATH  (O04904), PYRC_ARCFU  (O28034), PYRC_AROAE  (Q5P6Y5), 
PYRC_AZOSB  (A1K3T5), PYRC_AZOVD  (C1DQV1), PYRC_BACAA  (C3P658), 
PYRC_BACAC  (C3L738), PYRC_BACAH  (A0RHR0), PYRC_BACAN  (Q81WF0), 
PYRC_BACC0  (B7JJX5), PYRC_BACC1  (Q732I1), PYRC_BACC2  (B7IUP8), 
PYRC_BACC3  (C1EPQ2), PYRC_BACC4  (B7H6M4), PYRC_BACC7  (B7HLM2), 
PYRC_BACCL  (P46538), PYRC_BACCN  (A7GRL3), PYRC_BACCQ  (B9IVW5), 
PYRC_BACCR  (Q819S1), PYRC_BACCZ  (Q636D8), PYRC_BACHK  (Q6HES6), 
PYRC_BACLD  (Q65JU9), PYRC_BACMK  (A9VTC8), PYRC_BACP2  (A8FD15), 
PYRC_BACSU  (P25995), PYRC_BREBN  (C0ZG41), PYRC_BUCA5  (B8D9C1), 
PYRC_BUCAI  (P57416), PYRC_BUCAP  (Q8K9L2), PYRC_BUCAT  (B8D7M3), 
PYRC_CARHZ  (Q3AC01), PYRC_CERS5  (A4WPB7), PYRC_CHESB  (Q11IA4), 
PYRC_CITBB  (B5EB50), PYRC_CITK8  (A8AI14), PYRC_CLOD6  (Q18C47), 
PYRC_CORGL  (Q8NQ39), PYRC_CROS8  (A7MG30), PYRC_CUPMC  (Q1LRD4), 
PYRC_CUPNH  (Q0KEE2), PYRC_CUPPJ  (Q475T7), PYRC_CUPTR  (B2AH54), 
PYRC_DELAS  (A9BSM4), PYRC_DESAH  (C0QJ54), PYRC_DESPS  (Q6AS41), 
PYRC_DESRM  (A4J556), PYRC_ECO24  (A7ZKG7), PYRC_ECO27  (B7UP76), 
PYRC_ECO45  (B7MIK3), PYRC_ECO55  (B7LFZ6), PYRC_ECO57  (Q8X8N8), 
PYRC_ECO5E  (B5YVT2), PYRC_ECO7I  (B7NL72), PYRC_ECO81  (B7MTJ3), 
PYRC_ECO8A  (B7M937), PYRC_ECOBW  (C4ZS02), PYRC_ECODH  (B1X9H5), 
PYRC_ECOHS  (A7ZZ20), PYRC_ECOK1  (A1A9V7), PYRC_ECOL5  (Q0TJ12), 
PYRC_ECOL6  (Q8FIR2), PYRC_ECOLC  (B1IV40), PYRC_ECOLI  (P05020), 
PYRC_ECOLU  (B7NAT7), PYRC_ECOSE  (B6I9D9), PYRC_ECOSM  (B1LIU8), 
PYRC_ECOUT  (Q1RD95), PYRC_EHRCJ  (Q3YRI2), PYRC_EHRCR  (Q2GH90), 
PYRC_ENT38  (A4W975), PYRC_ENTFA  (Q834E0), PYRC_ERWT9  (B2VDJ8), 
PYRC_ERYLH  (Q2NCC9), PYRC_ESCF3  (B7LT74), PYRC_GEODF  (B9M4S4), 
PYRC_GEOKA  (Q5L0U5), PYRC_GEOMG  (Q39US3), PYRC_GEOSL  (Q74DP4), 
PYRC_GEOSM  (C6DZ51), PYRC_GEOSW  (C5D8P8), PYRC_GEOTN  (A4IM31), 
PYRC_GEOUR  (A5GF42), PYRC_HAHCH  (Q2SCE3), PYRC_HALH5  (Q9K9V7), 
PYRC_HALHL  (A1WV00), PYRC_HALSA  (Q9HMH9), PYRC_HELAH  (Q17W17), 
PYRC_HELHP  (Q7VIJ1), PYRC_HELP2  (B6JLG3), PYRC_HELPH  (Q1CTU5), 
PYRC_HELPJ  (Q9ZLQ0), PYRC_HELPS  (B2UTP7), PYRC_HELPY  (P56465), 
PYRC_IDILO  (Q5QWC6), PYRC_JANSC  (Q28RK3), PYRC_LACLA  (Q9CGM7), 
PYRC_LACPL  (P77884), PYRC_LARHH  (C1D672), PYRC_LEPCP  (B1XWS5), 
PYRC_LISIN  (Q92AH1), PYRC_LISMC  (C1KWD6), PYRC_LISMF  (Q71YH9), 
PYRC_LISMH  (B8DDR5), PYRC_LISMO  (Q8Y663), PYRC_LISW6  (A0AJU2), 
PYRC_MACCJ  (B9EB67), PYRC_MARN8  (A1U3L1), PYRC_METAC  (Q8TSA6), 
PYRC_METFK  (Q1GYZ0), PYRC_METJA  (Q58885), PYRC_METMA  (Q8PVF4), 
PYRC_METTH  (O27199), PYRC_MICAN  (B0JQJ1), PYRC_NEIG1  (Q5F9Y1), 
PYRC_NEIG2  (B4RJT2), PYRC_NEIM0  (A9M2W6), PYRC_NEIMA  (Q9JVD6), 
PYRC_NEIMB  (Q9K0D1), PYRC_NEIMF  (A1KSU5), PYRC_NITEC  (Q0AFI1), 
PYRC_NITEU  (Q82WF3), PYRC_NITOC  (Q3J872), PYRC_ORYSJ  (Q0JJD1), 
PYRC_PEDPA  (Q03HB2), PYRC_PELPD  (A1AS12), PYRC_PELTS  (A5D1A4), 
PYRC_PHOLL  (Q7N5W0), PYRC_PHOPR  (Q6LPI7), PYRC_PICP2  (B1XI96), 
PYRC_PSE14  (Q48F12), PYRC_PSEA6  (Q15YC5), PYRC_PSEA7  (A6V1R9), 
PYRC_PSEA8  (B7UVV3), PYRC_PSEAB  (Q02QZ8), PYRC_PSEAE  (P72170), 
PYRC_PSEE4  (Q1IE05), PYRC_PSEF5  (Q4K747), PYRC_PSEFS  (C3KBZ0), 
PYRC_PSEMY  (A4XS41), PYRC_PSEP1  (A5VZH8), PYRC_PSEPF  (Q3K7J8), 
PYRC_PSEPG  (B0KUE9), PYRC_PSEPK  (Q88NW7), PYRC_PSEPW  (B1J4I2), 
PYRC_PSESM  (Q87XM1), PYRC_PSEU2  (Q4ZPJ8), PYRC_PSYIN  (A1SX20), 
PYRC_PYRAB  (Q9UXV6), PYRC_PYRFU  (Q8U4A0), PYRC_PYRHO  (O57740), 
PYRC_RALN1  (Q8Y249), PYRC_RALPJ  (B2UFJ8), PYRC_RHIE6  (B3Q0A1), 
PYRC_RHIEC  (Q2KCZ6), PYRC_RHIJ3  (Q1MM16), PYRC_RHILW  (B5ZNS1), 
PYRC_RHIME  (Q92SC7), PYRC_RHIR8  (B9J8H5), PYRC_ROSDO  (Q163V6), 
PYRC_RUEPO  (Q5LQ43), PYRC_RUEST  (Q1GFQ7), PYRC_SALA4  (B5F944), 
PYRC_SALAR  (A9MH00), PYRC_SALCH  (Q57QJ4), PYRC_SALDC  (B5FL01), 
PYRC_SALEP  (B5QY02), PYRC_SALG2  (B5RBD7), PYRC_SALHS  (B4TET5), 
PYRC_SALNS  (B4T2Z5), PYRC_SALPA  (Q5PGW5), PYRC_SALPB  (A9N5P9), 
PYRC_SALPC  (C0Q845), PYRC_SALPK  (B5BBC6), PYRC_SALSV  (B4TSS5), 
PYRC_SALTI  (Q8Z7L2), PYRC_SALTY  (P06204), PYRC_SHEAM  (A1S9L6), 
PYRC_SHEB2  (B8E4P5), PYRC_SHEB5  (A3D7V9), PYRC_SHEB8  (A6WK08), 
PYRC_SHEB9  (A9L3F5), PYRC_SHEDO  (Q12NL3), PYRC_SHEFN  (Q087W5), 
PYRC_SHEHH  (B0TRS6), PYRC_SHELP  (A3QAV2), PYRC_SHEON  (Q8EB40), 
PYRC_SHEPA  (A8H7J4), PYRC_SHEPC  (A4Y9S5), PYRC_SHEPW  (B8CT15), 
PYRC_SHESA  (A0L0B8), PYRC_SHESH  (A8FZC6), PYRC_SHESM  (Q0HLX7), 
PYRC_SHESR  (Q0HRV9), PYRC_SHESW  (A1RGK8), PYRC_SHEWM  (B1KEK5), 
PYRC_SHIB3  (B2TTK9), PYRC_SHIBS  (Q31ZB7), PYRC_SHIDS  (Q32ES3), 
PYRC_SHIF8  (Q0T5X0), PYRC_SHIFL  (Q83RT8), PYRC_SHISS  (Q3Z354), 
PYRC_SHOC1  (Q5WFJ0), PYRC_SINFN  (C3MF80), PYRC_SINMW  (A6U5N6), 
PYRC_SOLUE  (Q01V55), PYRC_SPHAL  (Q1GT81), PYRC_STAAC  (Q5HGN1), 
PYRC_STAAM  (P65905), PYRC_STAAN  (P65906), PYRC_STAAR  (Q6GHN4), 
PYRC_STAAS  (Q6GA12), PYRC_STAAW  (P65907), PYRC_STAEQ  (Q5HPZ0), 
PYRC_STAES  (Q8CPJ6), PYRC_STRP1  (Q9A071), PYRC_STRP3  (P0DD64), 
PYRC_STRP6  (Q5XCK2), PYRC_STRP8  (Q7CNB0), PYRC_STRPN  (Q97QN4), 
PYRC_STRPQ  (P0DD65), PYRC_STRR6  (Q8DPQ5), PYRC_STRT1  (Q5LZQ6), 
PYRC_STRT2  (Q5M4C1), PYRC_STUS1  (A4VIU5), PYRC_SULAC  (O08357), 
PYRC_SULSY  (B2V5I6), PYRC_SULTO  (Q970X5), PYRC_SYNC1  (Q3A449), 
PYRC_SYNFM  (A0LK22), PYRC_SYNS9  (Q3AYG9), PYRC_SYNSC  (Q3AKY8), 
PYRC_SYNY3  (P74438), PYRC_TERTT  (C5BNK6), PYRC_THEAC  (Q9HIM0), 
PYRC_THEAQ  (P96081), PYRC_THEMA  (Q9WYH0), PYRC_THET8  (Q5SK67), 
PYRC_THEVO  (Q97C35), PYRC_TRIL1  (B3E3I1), PYRC_USTMA  (P31301), 
PYRC_VARPS  (C5CMK6), PYRC_VIBA3  (B7VQP0), PYRC_VIBC1  (A7N655), 
PYRC_VIBCH  (Q9KL24), PYRC_VIBPA  (Q87J46), PYRC_VIBVU  (Q8D3T9), 
PYRC_VIBVY  (Q7MFB3), PYRC_WOLTR  (Q5GSJ0), PYRC_WOLWR  (C0R5K8), 
PYRC_YEAST  (P20051)
» more

UniProtKB/Swiss-Prot
False negative sequences
64 sequences

PYRC_ACET2  (A3DE07), PYRC_AERPE  (Q9YFI5), PYRC_CALBD  (B9MS22), 
PYRC_CALS4  (Q8R9R6), PYRC_CALS8  (A4XKT2), PYRC_CHLTE  (Q8KDK5), 
PYRC_CLOAB  (Q97LN7), PYRC_CLOBA  (B2UW91), PYRC_CLOBB  (B2TNG1), 
PYRC_COXBR  (A9NA67), PYRC_DEIRA  (Q9RVC3), PYRC_EDWI9  (C5BA73), 
PYRC_ELUMP  (B2KCN5), PYRC_ENDTX  (B1GYY7), PYRC_FUSNN  (Q8RG88), 
PYRC_HELPG  (B5Z6V2), PYRC_KLEP3  (B5XXJ5), PYRC_KLEP7  (A6T7D6), 
PYRC_LACAC  (Q5FJB8), PYRC_LACDA  (Q1G867), PYRC_LACDB  (Q047M6), 
PYRC_LACGA  (Q043B0), PYRC_LACH4  (A8YVZ5), PYRC_LACJO  (Q74J32), 
PYRC_LACLE  (P48795), PYRC_LATSS  (Q38X26), PYRC_LEIXX  (Q6AF87), 
PYRC_LIGS1  (Q1WVB1), PYRC_LIMF3  (B2GD08), PYRC_LYSSC  (B1HQB9), 
PYRC_MARMS  (A6VXW9), PYRC_METKA  (Q8TXX9), PYRC_METST  (Q2NHZ6), 
PYRC_MYCBO  (Q7U057), PYRC_MYCLE  (Q9CCR4), PYRC_MYCTO  (P9WHL2), 
PYRC_MYCTU  (P9WHL3), PYRC_NOVAD  (Q2G9U3), PYRC_PARMW  (Q7U618), 
PYRC_PECAS  (Q6D698), PYRC_PECCP  (C6DKU3), PYRC_PYRAE  (Q8ZZC7), 
PYRC_RHOBA  (Q7UNR2), PYRC_RUBXD  (Q1AVY7), PYRC_RUMCH  (B8I770), 
PYRC_SACS2  (Q9UX05), PYRC_SCHPO  (Q9UTI0), PYRC_SERP5  (A8GD09), 
PYRC_STRCO  (Q9KXR3), PYRC_SYNAS  (Q2LVI3), PYRC_SYNR3  (A5GR03), 
PYRC_THEKO  (Q5JJ91), PYRC_THEP3  (B0KA35), PYRC_THEPX  (B0K2E8), 
PYRC_YERE8  (A1JN45), PYRC_YERP3  (A7FH16), PYRC_YERPA  (Q1C6L6), 
PYRC_YERPB  (B2K767), PYRC_YERPE  (Q8ZFU4), PYRC_YERPG  (A9R7Y6), 
PYRC_YERPN  (Q1CI09), PYRC_YERPP  (A4TLT2), PYRC_YERPS  (Q669K2), 
PYRC_YERPY  (B1JHH4)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

PYRC_SERMA  (Q9S3S1)

		
UniProtKB/Swiss-Prot
False positive sequences
14 sequences

ALLB_DEIGD  (Q1J391), ALLB_HALH5  (Q9KAH8), ALLB_RUBXD  (Q1AS71), 
GROU_DROME  (P16371), IGA_NEIGO   (P09790), IGSF2_HUMAN (Q93033), 
LEVR_BACSU  (P23914), SPA11_HUMAN (Q86U17), UGPC_CUPNH  (Q0K998), 
URE1_HALMA  (Q75ZQ5), URE1_NATPD  (Q3IRZ5), VPS10_ASPFC (B0YA89), 
VPS10_ASPFU (Q4WBM1), VPS10_NEOFI (A1DAY6)
» more

PDB
[Detailed view]
85 PDB

1J79; 1XGE; 1XRF; 1XRT; 2E25; 2EG6; 2EG7; 2EG8; 2Z00; 2Z24; 2Z25; 2Z26; 2Z27; 2Z28; 2Z29; 2Z2A; 2Z2B; 3D6N; 3GRI; 3JZE; 3MJM; 3MPG; 4BJH; 4BY3; 4C6B; 4C6C; 4C6D; 4C6E; 4C6F; 4C6I; 4C6J; 4C6K; 4C6L; 4C6M; 4C6N; 4C6O; 4C6P; 4C6Q; 4YIW; 5VGM; 5YNZ; 6GDD; 6GDE; 6GDF; 6HFD; 6HFE; 6HFF; 6HFH; 6HFI; 6HFJ; 6HFK; 6HFL; 6HFN; 6HFP; 6HFQ; 6HFR; 6HFS; 6HFU; 6HG1; 6L0A; 6L0B; 6L0F; 6L0G; 6L0H; 6L0I; 6L0J; 6L0K; 7CA0; 7CA1; 7UOF; 8GVZ; 8GW0; 8PBE; 8PBG; 8PBH; 8PBI; 8PBJ; 8PBK; 8PBM; 8PBN; 8PBP; 8PBQ; 8PBS; 8PBT; 8PBU
» more