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PROSITE entry PS00508


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00508
Entry name [info] NI_HGENASE_L_2
Accession [info] PS00508
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-JAN-2008 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00400

Name and characterization of the entry

Description [info] Nickel-dependent hydrogenases large subunit signature 2.
Pattern [info] 
[FY]-D-[PI]-[CU]-[LIMAV]-[ASG]-C-x(2,3)-H.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 34 in 34 different sequences
Number of true positive hits 34 in 34 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 6
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 85.00 %

Comments [info]

Taxonomic range [info] Archaea, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] nickel at position 4
Site [info] nickel at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 34 sequences 

FRHA_METBF  (P80489), FRHA_METJA  (Q60338), FRHA_METTH  (P19496), 

FRHA_METVO  (Q00390), HOXH_CUPNH  (P22320), HYD1A_PYRFU (E7FI44), 
HYD2A_PYRFU (E7FHC4), MBHL_AFIC5  (O33406), MBHL_ALCHY  (P33374), 
MBHL_AZOCH  (P18191), MBHL_AZOVI  (P21949), MBHL_BRADU  (P12636), 
MBHL_CITFR  (Q46046), MBHL_CUPNH  (P31891), MBHL_ECOLI  (P0ACD8), 
MBHL_RHILV  (P18636), MBHL_RHOCA  (P15284), MBHL_RUBGE  (P17632), 
MBHL_SHIFL  (P0ACD9), MBHL_WOLSU  (P31883), MBHM_ECO57  (P0ACE1), 
MBHM_ECOLI  (P0ACE0), MBHM_SHIFL  (P0ACE2), MVHA_METFE  (Q49179), 
MVHA_METTH  (Q50783), MVHA_METTM  (P60227), PHNL_MEGGA  (P12944), 
PHNL_NITV9  (P21852), PHNL_SOLFR  (P18188), PHSL_DESBA  (P13065), 
VHCA_METVO  (Q00404), VHOA_METMA  (Q50249), VHTA_METMA  (F1SVF8), 
VHUU_METKA  (P0C1V6)
» more

UniProtKB/Swiss-Prot
False negative sequences		 6 sequences 

VHCA_ARCPA  (P84625), VHUA_METJA  (Q58592), VHUA_METVO  (Q00407), 

VHUU_METJA  (P81335), VHUU_METMP  (P0C1V5), VHUU_METVO  (Q00410)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

HOXH_RHOOP  (P22661), PHSL_DESNO  (P13066)


				
	

	

		PDB
[Detailed view]		
		
			86 PDB
			


			1CC1; 1FRF; 1FRV; 1H2A; 1H2R; 1UBH; 1UBJ; 1UBK; 1UBL; 1UBM; 1UBO; 1UBR; 
			
				1UBT; 1UBU; 1WUH; 1WUI; 1WUJ; 1WUK; 1WUL; 1YQ9; 1YQW; 1YRQ; 2FRV; 3CUR; 
				3CUS; 3H3X; 3RGW; 3UQY; 3USC; 3USE; 4GD3; 4IUB; 4IUC; 4IUD; 4TTT; 4U9H; 
				4U9I; 4UCQ; 4UCW; 4UCX; 4UE2; 4UE3; 4UE6; 4UEW; 4UPE; 4UPV; 4UQL; 4UQP; 
				4URH; 5A4F; 5A4M; 5D51; 5JRD; 5LMM; 5LRY; 5MDJ; 5MDK; 5MDL; 5XLE; 5XLF; 
				5XLG; 5XLH; 5Y4N; 6EHQ; 6EHS; 6EN9; 6FPI; 6FPO; 6FPW; 6G7M; 6G7R; 6G94; 
				6GAL; 6GAM; 6GAN; 6RP2; 6SYO; 7NEM; 7ODG; 7ODH; 8POU; 8POV; 8POW; 8POX; 
				8POZ; 8W6X
			
			

			» more