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Entry: PS00509

General information about the entry

Entry name [info] RAS_GTPASE_ACTIV_1
Accession [info] PS00509
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-DEC-2004 DATA UPDATE;
13-FEB-2019 INFO UPDATE.
PROSITE Doc. [info] PDOC00438

Name and characterization of the entry

Description [info] Ras GTPase-activating proteins domain signature.
Pattern [info] 
[GSNA]-x-[LIVMF]-[FYCI]-[LIVMFY]-R-[LIVMFY](2)-[GACNS]-[PAV]-[AV]-[LIV]-
[LIVM]-[SGANT]-P.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2019_02 which contains 559'228 sequence entries.


Total number of hits 43 in 43 different sequences
Number of true positive hits 43 in 43 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 13
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 76.79 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 43 sequences 

BUD2_CANAL  (Q5A506    ), BUD2_YEAST  (P33314    ), DAB2P_HUMAN (Q5VWQ8    ), 

DAB2P_MOUSE (Q3UHC7    ), DAB2P_RAT   (Q6P730    ), GAP1_CAEEL  (Q22720    ), 
GAP1_DROME  (P48423    ), GAP1_SCHPO  (P33277    ), GAP2_CAEEL  (Q8MLZ5    ), 
GAP2_DROME  (Q8T498    ), IQGA1_HUMAN (P46940    ), IQGA1_MOUSE (Q9JKF1    ), 
IQGA2_HUMAN (Q13576    ), IQGA2_MOUSE (Q3UQ44    ), IQGA3_HUMAN (Q86VI3    ), 
IRA1_YEAST  (P18963    ), IRA2_YEAST  (P19158    ), NF1_HUMAN   (P21359    ), 
NF1_MOUSE   (Q04690    ), NF1_RAT     (P97526    ), NGAP_DICDI  (Q54Y08    ), 
NGAP_HUMAN  (Q9UJF2    ), RAS4B_HUMAN (C9J798    ), RASA1_BOVIN (P09851    ), 
RASA1_HUMAN (P20936    ), RASA1_RAT   (P50904    ), RASA2_HUMAN (Q15283    ), 
RASA2_MOUSE (P58069    ), RASA2_RAT   (Q63713    ), RASA3_BOVIN (Q28013    ), 
RASA3_HUMAN (Q14644    ), RASA3_MOUSE (Q60790    ), RASA3_RAT   (Q9QYJ2    ), 
RASL1_HUMAN (O95294    ), RASL1_MOUSE (Q9Z268    ), RASL2_HUMAN (O43374    ), 
RASL2_MOUSE (Q6PFQ7    ), RASL3_BOVIN (A6QQ91    ), RASL3_HUMAN (Q86YV0    ), 
RASL3_MOUSE (Q8C2K5    ), SYGP1_HUMAN (Q96PV0    ), SYGP1_MOUSE (F6SEU4    ), 
SYGP1_RAT   (Q9QUH6    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 13 sequences 

GAPA_DICDI  (O00899    ), GAPD1_BOVIN (A5D794    ), GAPD1_HUMAN (Q14C86    ), 

GAPD1_MOUSE (Q6PAR5    ), GAPD1_XENLA (A2RV61    ), IQG1_CANAL  (Q5AH02    ), 
IQG1_YEAST  (Q12280    ), NFAA_DICDI  (Q55AR6    ), RGAA_DICDI  (Q54K32    ), 
RME6_CAEBR  (A8WVM4    ), RME6_CAEEL  (Q9GYH7    ), RME6_DROME  (Q9VZ08    ), 
RME6_DROPS  (Q29HW3    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

NF1_CHICK   (P35608    )


				
	

	

		PDB
[Detailed view]		
		
			5 PDB
			


			1NF1; 1WER; 1WQ1; 3BXJ; 5CJP
				
	





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